Temporary Bone And Matrix Scientist New Rockville, MD

Axle Info; Bethesda (MD); On-site; USD 50,000 - 61,000; Full time

Benefits offered by this job

Temporary position

Job summary

Axle is seeking a temporary Bone and Matrix Scientist to join the NIH NICHD team at Bethesda, MD, supporting research on bone tissue and cell development. The role combines planning, design, and execution of experiments with independent data analysis and reporting.

The candidate will perform molecular and cellular biology techniques, mouse work, and assay development, while contributing to publications and scientific presentations; safety and notebook integrity are emphasized.

Qualifications

• Master’s degree in Molecular Biology, Physiology, Cell Biology, or closely related discipline.
• Ph.D. strongly preferred in Physiology, Cell Biology, Molecular Biology, or related discipline.

Responsibilities

• Plan, design, and conduct complex research experiments in bone biology and cell development.
• Perform molecular and cellular biology techniques including PCR, qPCR, RT-PCR, RT-qPCR, cloning, gel electrophoresis, and nucleic acid purification.
• Conduct mammalian, primary and bacterial cultures; perform transfections and related procedures.
• Analyze data, prepare reports, abstracts, and manuscripts for publication.
• Train staff on laboratory practices and safety; maintain accurate electronic lab notebooks.

Skills

Bone biology

PCR

Cell culture

Molecular biology

Mouse handling

Data analysis

Lab safety

Education

Master’s degree in Molecular Biology or related

Ph.D. in Physiology/Cell Biology/Molecular Biology

Tools

PCR/qPCR equipment

Gel electrophoresis

Western blotting

Genotyping

Job description

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

(ID: 2026-3626)

Axle is seeking a Temporary Bone and Matrix Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the National Institute of Child Health and Human Development located in Bethesda, MD.

Position Overview

We are seeking a highly qualified Bone and Matrix Scientist to support laboratory research activities within the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

This position will support the planning, design, and execution of research experiments within the laboratory’s broader research program. The Bone and Matrix Scientist will conduct independent research with an emphasis on bone tissue and bone cell development, evaluate new laboratory techniques and technologies, analyze experimental data, and contribute to scientific reports, presentations, and manuscripts.

Key Responsibilities

• Plan, design, and conduct complex research experiments requiring broad knowledge of scientific theories, principles, and laboratory methods.
• Perform research involving bone tissue, bone cell development, physiology, cell biology, and molecular biology.
• Independently direct and conduct high-priority research projects, including projects focused on developing novel research treatments.
• Advance laboratory research through the development of new procedures, methodologies, and scientific discoveries.
• Evaluate new laboratory techniques, instruments, and software for potential incorporation into existing standard operating procedures.
• Collaborate with investigators and laboratory staff to interpret experiments and evaluate research findings.
• Review scientific data and determine whether new research programs or projects can be developed from an idea or existing data package.
• Design, develop, optimize, and validate experimental assays using a range of laboratory techniques.
• Confirm assay results and develop appropriate secondary assays.
• Research scientific literature and recommend alternative or complementary experimental approaches.
• Troubleshoot difficult screening targets and propose, design, and test alternative assays.
• Perform molecular and cellular biology techniques, including PCR, qPCR, RT-PCR, RT-qPCR, molecular cloning, gel electrophoresis, and nucleic acid extraction and purification.
• Perform protein analysis techniques, including SDS‑PAGE, Western blotting, Southern blotting, and ELISA.
• Conduct mammalian cell culture, primary cell culture, bacterial culture, transfections, and related laboratory procedures.
• Perform mouse handling, tissue dissection, tissue sectioning, animal imaging, and genotyping.
• Prepare and submit laboratory animal study protocols for review and approval.
• Provide basic and advanced training to staff on animal care and use procedures.
• Train laboratory personnel in the proper use of laboratory instruments and equipment.
• Advise and assist laboratory users with experimental design, instrumentation, data acquisition, data analysis, and preparation of publication‑quality figures.
• Conduct bioinformatics and statistical analyses to support research projects.
• Oversee research data quality and analyze and interpret experimental results.
• Assemble and prepare data for scientific abstracts, presentations, manuscripts, and publications.
• Write technical reports and contribute to the preparation and submission of scientific manuscripts.
• Prepare PowerPoint presentations for laboratory meetings, scientific conferences, and other research‑related activities.
• Present project updates and research findings to laboratory members on an ad hoc basis.
• Maintain a detailed, accurate, and current electronic laboratory notebook documenting all experiments and findings.
• Coordinate with junior staff to modify and optimize research protocols.
• Support the maintenance of adequate laboratory space, equipment, and facilities for ongoing and projected research studies.
• Follow all applicable laboratory safety, animal care, data integrity, and NIH research requirements.

Qualifications

Education

• Master’s degree in Molecular Biology, Physiology, Cell Biology, or a closely related scientific discipline required.
• Ph.D. in Physiology, Cell Biology, Molecular Biology, or a related discipline strongly preferred.

Experience

• Demonstrated experience conducting independent biomedical laboratory research.
• Experience with techniques related to bone tissue and bone cell development required.
• Experience designing, conducting, analyzing, and interpreting complex scientific experiments.
• Experience working with mouse models and preparing or supporting laboratory animal study protocols.
• Experience developing scientific manuscripts, technical reports, abstracts, and research presentations.
• Experience training laboratory personnel in research techniques, instrumentation, and animal care procedures preferred.

Skills

• Strong knowledge of bone biology, cell biology, molecular biology, and physiology.
• Proficiency with mouse handling, tissue dissection, tissue sectioning, animal imaging, and genotyping.
• Proficiency with PCR, qPCR, RT-PCR, RT-qPCR, molecular cloning, and gel electrophoresis.
• Experience with nucleic acid extraction, DNA and RNA purification, and nucleic acid quantification.
• Experience with cell culture, primary cell culture, bacterial culture, and transfection techniques.
• Experience with SDS‑PAGE, Western blotting, Southern blotting, ELISA, and microarray techniques.
• Strong quantitative, statistical, bioinformatics, and scientific data‑analysis skills.
• Ability to independently design experiments, troubleshoot assays, and recommend alternative research approaches.
• Strong scientific writing, manuscript preparation, and data‑presentation skills.
• Strong written and verbal communication skills.
• Ability to collaborate effectively with investigators, scientists, junior research staff, and laboratory personnel.
• Strong organizational skills and attention to detail.
• Ability to maintain complete and accurate electronic laboratory records.
• Proficiency with Microsoft PowerPoint, Outlook, and NIH systems such as POTS.

Work Environment:

PLEASE NOTE: This position is a TEMP position needed from December 2026 to February 2027.

This position is based at the NIH campus in Bethesda, Maryland and is scheduled for approximately 40 hours per week. Telework may be available based on laboratory and project requirements.

Work may be scheduled Monday through Saturday depending on experimental needs.

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: [e-mail]

This role has a market‑competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range

$55 - $55 USD

Voluntary Self‑Identification

For government reporting purposes, we ask candidates to respond to the below self‑identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Axle’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.