Temporary Associate Scientist, Vector Process Development

Regeneron; Cambridge (MA); On-site; USD 60,000 - 90,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc. in Cambridge, MA is seeking a Temporary Associate Scientist to join the Vector Process Development team. You will support lab activities for lentiviral vector purification and assist with purification technology development for clinical cell therapy programs.

The role involves independent work, ELN data management, and collaboration to optimize purification steps and transfer processes, contributing to the current pipeline projects.

Qualifications

• BS/MS in Bioengineering, Chemical Engineering, Biology, Chemistry, or related sciences.
• Independent lab work experience in biotech/pharma settings.
• Experience with purification of proteins or viral vectors.

Responsibilities

• Execute research-grade lentiviral vector purification operations per written protocols.
• Perform routine lab activities and equipment maintenance; manage inventories.
• Create sampling plans and prepare samples for analytical testing.
• Support purification experiments to assess process changes and new tech.
• Record data and maintain electronic lab notebooks diligently.

Skills

Bioengineering

Chemical Engineering

Biology

Chemistry

Related sciences

Independent lab work

ELN experience

Protein/viral purification

AKTA chromatography

Data recording

Collaboration

Problem-solving

Education

BS/MS in Bioengineering, Chemical Engineering, Biology, Chemistry, or related sciences

Tools

AKTA Chromatography

ELN systems

Job description

Temporary Associate Scientist, Vector Process Development - R51989

Location

Cambridge, MA

Position Description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Temp, Associate Scientist to join our Vector Process Development team within Cell Medicines. This team is responsible for the development of robust, cost-effective, scalable, and transferable lentiviral vector manufacturing for clinical cell therapy programs. In this role, you will have the opportunity to directly support process development lab activities needed to deliver current pipeline cell therapy programs and assist with lab work geared toward novel purification process technology development.

Roles Responsibilities

• Execute research grade lentiviral vector purification operations, including harvest, chromatography, concentration and diafiltration, and aseptic filling steps, according to written protocols
• Conduct routine laboratory activities, including buffer preparation, tubing assembly preparation, equipment operation and maintenance, materials inventory management, and laboratory organization
• Create and organize sampling plans; prepare and manage submission of samples to analytical testing laboratories
• Support team members in the execution of purification experiments to assess the impact of process changes and new technologies
• Generate, record, and maintain data in an organized way, including electronic lab notebook maintenance

Skills

• BS/MS in Bioengineering, Chemical Engineering, Biology, Chemistry, or related sciences, with 0 years (MS) or 2 years (BS) of relevant experience in the biotechnology or pharmaceutical industry
• Prior experience working independently in a laboratory environment
• Comfortable using electronic laboratory notebook (ELN) systems to record, manage, and store data
• Good interpersonal and communication skills, with the ability to plan ahead and coordinate with colleagues to get a job done
• Prior experience with purification of proteins, viral vectors, nucleic acids, or other biologics
• Prior experience with Akta chromatography systems
• Independently motivated, detail-oriented, with good problem-solving ability; asks questions to gain knowledge and comprehension

Education

• BS/MS in Bioengineering, Chemical Engineering, Biology, Chemistry, or related sciences