Technologist II

Precision Medicine Group; Houston (TX); On-site; USD 46,000 - 68,000; Full time

Job summary

Precision Medicine Group seeks a Technologist II (Molecular) to develop and perform assays for molecular biology projects, including assay development, validation and execution in a CLIA-regulated lab. The role requires training staff and supporting SOP improvements.

The ideal candidate has a strong molecular biology background, experience with RNA/DNA extractions, qPCR or NGS, and a track record of accurate data generation.

Qualifications

• Bachelor’s degree in Life Sciences or related discipline.
• 2+ years of related laboratory experience.
• Experience with molecular biology workflows and QC.
• Knowledge of CLIA/GLP standards and documentation.

Responsibilities

• Develop and execute molecular biology assays per SOPs.
• Perform RNA/DNA extractions, qPCR and related tests.
• Run QC samples and process clinical specimens.
• Maintain reagents stock and instrument upkeep.
• Train staff and assist in method validation.

Skills

Molecular biology

RNA/DNA extraction

qPCR/NGS techniques

Lab maintenance

Documentation & CLIA knowledge

Education

Bachelor’s Degree in Life Sciences

Tools

qPCR instrumentation

NGS platforms

Job description

Technologist II (Molecular) will need to have a broad skill set and good troubleshooting skills within the laboratory setting. Be able to work with scientists to develop and perform assays for molecular biology projects through assay development, validation, and execution phases in a timely manner. Perform assays according to SOPs and support development of new procedures and improvement of existing SOPs. Also, familiar and operating under CLIA. Responsible for training other staff.

Essential functions of the job include but are not limited to:

• Skilled with molecular biology techniques
• Ability and willingness to learn and execute techniques related to RNA and DNA extractions, qPCR, NGS or other molecular biology platforms
• Run quality control samples; Run clinical samples and generate data
• Maintain a stock of all needed reagents and consumables
• Perform daily, weekly, monthly instrument maintenance and trouble‑shooting as required
• Flexibility in shift work
• Work with scientists to carry out qualification of assays for new projects
• Work with QA (Quality Assurance) to perform good documentation, and to ensure the lab operating under CLIA, GLP and GCP standards
• Train new personnel on project related assays, daily lab work and SOPs.
• Participate in cross‑functional process improvement activities
• May need to complete freezer transfers, generate reports, and coordinate with QC and entry of locations into the BSI
• Other duties as assigned

Qualifications:

• Bachelor’s Degree (Life Sciences, Biology or other related discipline)
• More than 2 years of prior related laboratory experience

Other Required:

• Position requires occasional long hours, work on the evenings, weekends, and holidays.
• Someone who is a good team player, detail‑oriented and organized, can work under pressure and has good oral and written communication skills
• This person can contribute to quality control of reagents through a variety of tests, and writing of SOPs
• Superior attention to detail, ability and willingness to effectively scrutinize data and ability to work well in a group environment
• Must possess strong computational skills, preferably experienced with Word, Excel, Power Point, etc.
• Excellent use of judgment and discretion required
• Ability to lift and carry between 1-15 lbs.; Ability to lift up to 50 lbs. overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; May be exposed to a cold freezer environment (Freezer temperatures range between -20ºC -196ºC)
• Must be able to read, write, speak fluently and comprehend the English language

Preferred:

• 4 years of related experience, preferably in NGS core facility or NGS lab.
• MB (ASCP) certification a plus but not a requirement
• Wet lab experience in the entire NGS workflow (Illumina or Ion Torrent), from library preparation to sequencing.
• Experience in quantitative PCR (qPCR), digital droplet PCR (ddPCR) and NanoString is a plus.
• Experience in DNA and RNA extractions from a variety of sources is a plus.
• Solid lab experience with multiple skill sets
• A solid understanding of current GLP or CAP/CLIA/ISO standards
• Have a documentation background in a laboratory setting with respect to regulatory guidelines (cGMP, cGLP or ISO) and SOPs

Precision is required by law in some states or cities to include a reasonable estimate of the compensation range for this role. This compensation range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to: skill sets, experience and training, licensure and certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled.

Reasonable estimate of the current range

$33.03 - $49.57 USD

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Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at [e-mail].

CANDIDATES MUST BE LEGALLY AUTHORIZED TO WORK IN THE COUNTRY OF EMPLOYMENT WITHOUT EMPLOYER SPONSORSHIP.