SVP, Late-Stage Oncology Development & Portfolio Strategy

Revolution Medicines, Inc.; San Francisco (CA); On-site; USD 419,000 - 523,000; Full time

Job summary

Revolution Medicines, Inc. in Redwood City, CA, seeks a Senior Vice President of Late-Stage Clinical Development to shape the portfolio strategy and lead registrational and Phase 3 efforts.

This executive reports to the Chief Medical Officer and builds a high-impact late-stage organization across assets and indications. The role oversees trial design, regulatory interactions, and collaboration with cross-functional partners to influence standard of care in difficult tumors.

Qualifications

• MD or MD/PhD trained as a medical oncologist.
• Substantial late-stage oncology development experience including registrational and Phase 3 programs and global regulatory filings.
• Depth in pancreatic, colorectal or lung cancer strongly preferred.
• Track record leading development teams across multiple concurrent assets.
• Demonstrated ability to build and structure a clinical development organization, including hiring program leaders.
• Strong scientific judgment and credibility to guide experienced development leaders.
• Effective operating in a fast-moving, evolving organization with senior stakeholders alignment.
• Motivated by pipeline impact and changing standard of care.

Responsibilities

• Drive the late-stage clinical development strategy across the RAS(ON) portfolio and map it into an integrated company development plan.
• Own registrational and Phase 3 trials across all programs and assets, from design through readout and submission support.
• Shape indication sequencing, study design, endpoint selection and combination strategy with cross-functional partners.
• Lead, develop and grow the Global Development Team Leads and guide their clinical development plans.
• Build a late-stage organization with clear program ownership and scalable team structure.
• Partner with regulatory affairs on global filings and lifecycle planning.
• Collaborate on portfolio strategy and prioritization with senior leadership.
• Engage investigators and key opinion leaders on the company's late-stage programs.

Skills

Late-stage oncology development

Leadership in development teams

Global regulatory filings

Strategic portfolio planning

Team leadership

Education

MD or MD/PhD

Medical oncologist training

Job description

Revolution Medicines, Inc. in Redwood City, CA, seeks a Senior Vice President of Late-Stage Clinical Development to shape the portfolio strategy and lead registrational and Phase 3 efforts.

This executive reports to the Chief Medical Officer and builds a high-impact late-stage organization across assets and indications. The role oversees trial design, regulatory interactions, and collaboration with cross-functional partners to influence standard of care in difficult tumors.