Strategic Sourcing Associate Director

Vertex Pharmaceuticals Inc (US); United States; Hybrid; USD 146,000 - 218,000; Full time

Job summary

Vertex Pharmaceuticals Inc (US) is seeking an Associate Director of Strategic Sourcing for CGT Raw Materials at its Boston, MA headquarters. The role focuses on sourcing strategies, supplier governance, and risk mitigation across development to commercial manufacturing, with a strong emphasis on collaboration with cross-functional teams.

The ideal candidate will bring 8–10 years of CGT sourcing experience, advanced negotiation skills, and a track record in driving cost savings and supplier

Qualifications

• Minimum 8–10 years of strategic sourcing, procurement, supplier management, or related CGT experience in biopharmaceuticals.
• Bachelor’s degree in biology, biochemistry, chemistry, chemical engineering, biotechnology, pharmaceutical sciences, supply chain, business or related field; advanced degree or certifications a plus.
• Proven track record negotiating contracts, managing supplier relationships, and driving cost savings.

Responsibilities

• Partner with Development, Manufacturing, Quality, Regulatory, and Finance to define CGT raw material category strategies.
• Lead RFx, supplier assessments, negotiations, and long-term planning for CGT materials.
• Manage key suppliers and CDMOs to ensure quality, continuity, and cost efficiency.
• Develop and implement continuous improvement and digital enablement in sourcing processes.

Skills

Influence Sr. Leadership

Strategic Sourcing

Contract Negotiation

Project Management

Public Speaking

Education

Bachelor’s degree in biology/chemistry/biotech/supply chain

Tools

Power BI

Tableau

ERP systems

e-Sourcing tools

Job description

Job Description General Summary

As the Associate Director of Strategic Sourcing for Cell and Gene Therapy (CGT) Raw Materials, you will be part of a fast-growing and innovative organization at the company’s world headquarters in Boston, MA. The department is committed to a trusting and collaborative culture where growth and development are valued. We engage proactively with stakeholders to understand their needs and deliver results for our company and for patients. If you are looking for an entrepreneurial, hands-on, team-oriented environment where you can make a meaningful impact, this is the right place for you. The role is responsible for raw materials sourcing categories essential to the development and manufacturing of Cell and Gene Therapy products. This position requires a strong understanding of CGT raw material technologies, functionality, specifications, supplier and CDMO landscapes, industry regulations, quality expectations, capacity dynamics, and emerging trends to ensure robust supplier partnerships, uninterrupted supply of high-quality materials and services, risk mitigation, and competitive value. You will collaborate with business partners across Development, Manufacturing, internal manufacturing sites, external contract manufacturing sites as needed, Quality, Technical Operations, Supply Chain, Finance, Legal, and other functions to define and drive CGT raw material category strategies that support development-stage, clinical, and commercial manufacturing needs. You will support the management of key strategic suppliers to drive continuous improvement, resolve complex supply issues, and identify opportunities that create exceptional value for Vertex and, ultimately, for patients. You will be a lifelong learner with curiosity and adaptability, continually expanding beyond the scope of your area of responsibility as part of self-development. This role will have high visibility across the organization, so the ability to effectively communicate with Senior Executive and technical leaders is crucial. Execution responsibilities include CGT raw materials market analysis and due diligence, supplier assessments, RFx development, negotiations, competitive price and cost analysis, financial analysis and long-term planning, contract development, ongoing supplier management, internal manufacturing site support, external contract manufacturing site support as needed, and risk management. Additional focus will be placed on optimizing internal sourcing processes, workflows, interfaces, and technology-enabled sourcing approaches to reduce delivery timelines and costs in support of corporate objectives, manufacturing continuity, and industry best practices. This position is based in our Boston, MA office, located in the Seaport area. This role requires a hybrid work schedule: 3 days in office & 2 days remote on a weekly basis. This role will require some travel to other facilities to establish/maintain key business stakeholder and supplier relationships as well as to support specific strategic initiatives.

Key Responsibilities

• Business Partnering – develop strong, trusting, and influential relationships with stakeholders, understand business objectives, bring supplier and marketplace expertise, collaborate on multi-year strategic and operational plans, and drive business outcomes.
• Global Category Management – including the development and management of category and sourcing strategies, management of strategic supplier relationships and performance management, in addition to tactical RFx activities.
• Sourcing Strategy Development – co‑develop and implement sourcing strategies with business units, internal manufacturing sites, and external contract manufacturing sites as needed to enable CGT raw material needs across research, development, clinical manufacturing, commercial manufacturing, lifecycle management, and business continuity. This includes identifying and selecting critical raw material suppliers and CDMO partners where relevant, negotiating contracts, influencing network strategy, and managing supplier relationships.
• Supplier Relationship Management – cultivate and maintain strong relationships with key CGT raw material, specialty material, technology, and CDMO suppliers. Negotiate contracts and agreements to secure favorable terms while ensuring alignment with quality, technical, regulatory, and service expectations. Collaborate with suppliers to identify opportunities for risk mitigation, resilience, cost savings, process improvement, capacity access, technical support, and innovation. Partner with external manufacturing, supply chain, process development, quality, and other stakeholders to maintain appropriate supplier governance.
• Risk Mitigation – assess and mitigate risks associated with CGT raw materials, including supplier capacity, quality requirements, regulatory expectations, technical dependencies, manufacturing site needs, and single-source exposures. Proactively identify potential disruptions and develop contingency and resiliency plans to help ensure development progress and continuity of manufacturing supply.
• Cross-functional Collaboration – work closely with Development, Manufacturing, internal manufacturing sites, external manufacturing, Quality, Vendor Quality, Technical Operations, Supply Chain, Regulatory Affairs, Finance, Legal, and other functions to align sourcing activities with CGT program needs, production schedules, product specifications, supplier qualification requirements, and regulatory expectations.
• Market Analysis – stay informed about market trends, supplier capabilities, capacity dynamics, emerging technologies, regulatory developments, and quality expectations related to CGT raw materials and specialty materials. Conduct market analysis, supplier assessments, and benchmarking to identify opportunities, risks, and potential strategic partnership models.
• Continuous Improvement and Digital Enablement – implement continuous improvement initiatives to streamline sourcing processes, enhance efficiency, and drive operational excellence. Leverage data analytics, performance metrics, AI-enabled sourcing approaches, supplier intelligence, automation, and technology-enabled tools to monitor supplier performance, improve decision-making, and identify areas for improvement.
• Financials – support annual budget process. Provide cost guidance to inform to LRP (Long Range Planning). Evaluate Bill of Material (BOMs) and understand total COGs to identify opportunities and risks.

Knowledge and Skills

Demonstrated ability to influence Sr. Leadership to drive Sourcing’s value; gain a "Seat at the table" with stakeholders. Deep understanding of Category Management within specific areas of expertise; able to manage and drive all aspects of Strategic Sourcing including strategy development, RFx execution, negotiation, contract execution, supplier performance management, and business stakeholder management. Expertise in complex supplier negotiations and supplier management activities. Expertise in sourcing, contracting, and managing suppliers that provide critical CGT raw materials, specialty materials, technologies, and related manufacturing support services, including supplier governance within internal and external manufacturing environments. Strong analytical capabilities (data analysis and benchmarking research); expertise working with data analytical/reporting tools such as Power BI, Tableau, etc. Able to generate necessary data and reports to support their activities. Ability to understand and support sourcing digitization needs, including adoption of AI-based sourcing, contracting, supplier intelligence, data analytics, automation, and technology-enabled supplier management processes. Sound understanding and demonstrated use of Continuous Improvement tools (including Pareto Charts, Flow Diagrams, etc.) to drive process improvements. Strong project management and organizational skills. Able to lead teams in collaborative manner to drive successful outcomes. Collaboration extends beyond Business Partners and suppliers to include other functional areas including Legal, Compliance, Finance and more. Strong written and verbal communication skills; ability to clearly articulate opinions in concise and persuasive manner. Comfortable with public speaking with various audience levels, including Sr. Management. Strong knowledge and understanding of contract law, including all terms and conditions; seen as a trusted partner from Legal colleagues to provide valuable insight to potential risks across all types of agreements (i.e. CDAs, MSAs, etc). Ability to work in collaborative, team environment; ability to cultivate and maintain effective business partner relationships through earned respect and trust. Proficient in Microsoft Office, strong knowledge of ERP systems, and related e-Sourcing tools, including business intelligence and reporting platforms.

Qualifications

• Minimum of 8–10 years of experience in strategic sourcing, procurement, supplier management, manufacturing support, CDMO or external partner management, or related experience within the biopharmaceutical industry, with direct exposure to Cell and Gene Therapy raw materials, specialty materials, development and manufacturing support, supplier qualification, or related CGT supply categories.
• Bachelor’s degree in biology, biochemistry, chemistry, chemical engineering, biotechnology, pharmaceutical sciences, supply chain, business, or a related field preferred; advanced degree or relevant professional certifications are a plus.
• Proven track record of negotiating contracts, managing supplier relationships, and driving cost savings initiatives.
• Strong analytical and problem‑solving skills, with the ability to assess risks and develop effective mitigation strategies.
• Working knowledge of AI-based sourcing, contracting, supplier intelligence, data analytics, automation, or other technology-enabled sourcing approaches desired.
• In‑depth knowledge of Cell and Gene Therapy raw material requirements, supplier qualification considerations, manufacturing processes, development pathways, commercial product support, quality expectations, and relevant material technology needs desired.
• Excellent communication and interpersonal skills, with the ability to collaborate effectively across functions and levels of the organization.
• Understanding of raw material specifications, quality requirements, and regulatory standards relevant to current Good Manufacturing Practices.
• Familiarity with regulatory requirements, quality standards, and best practices in the pharmaceutical industry, including Good Manufacturing Practices (GMP) and ISO standards.
• Ability to travel as needed to meet with suppliers, visit manufacturing facilities, and attend industry conferences and events.

Pay Range

$145,600 - $218,400

Flex Designation

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]

Culture and Mission

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision‑making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Vertex has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1‑mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH‑dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex’s history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X. We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.