Stem Cell Senior Research Associate

Vertex Pharmaceuticals Inc (US); United States; On-site; USD 75,000 - 112,000; Full time

Benefits offered by this job

Medical, dental and vision benefits

Paid time off including a week-long公司

Educational assistance including loan/

Commuting subsidy

Matching charitable donations

401(k)

Job summary

Vertex Pharmaceuticals Inc. seeks a candidate to coordinate production of program-relevant cell types, including stem cell-derived islets, for use across research projects. The role involves 2D/3D culture, data interpretation, and strict SOP adherence to ensure quality.

The successful candidate will work in a team, communicate results, and adapt to timeline-driven workflows while rotating weekend shifts as needed.

Qualifications

• Masters Degree (or equivalent degree) in biological sciences and 0-2 years of relevant employment experience, or Bachelors Degree (or equivalent degree) in biological sciences and 4+ years of relevant employment experience
• Experience with advanced human cell culture techniques
• Ability and willingness to work rotating weekend shifts according to business needs

Responsibilities

• Culture human stem cells in 2D and/or 3D
• Completes experiments in a reliable, consistent manner
• Demonstrates a high level of attention to detail and follows SOP strictly
• Performs initial analysis of experimental data and interprets immediate experimental outcomes
• Records experiments and results in laboratory notebooks (including all electronic systems) in accordance with lab procedures
• Recognizes problems and suggests experiments to troubleshoot issues
• Develops new ideas to improve workflows, consistency and efficiency of the cell culture processes
• Clearly and effectively communicates (both written and verbal) results

Skills

Advanced human cell culture

Teachable mindset

Team collaboration

Data interpretation

Cross-functional teamwork

Education

Master's degree in biological sciences

Bachelor's degree in biological sciences

Tools

Electronic lab notebooks

Job description

General Summary

The successful candidate will work in a team setting and be responsible for coordinating production of program-relevant cell types such as stem cell-derived islets (SC-islet) for use across research team projects. This includes 2D and 3D culture of pluripotent stem cells as well as differentiation for in vitro and in vivo studies. A demonstrated strong understanding of best lab practices to ensure reliability, consistency, efficiency, and quality control, as well as dedication to lab bench work, are required.

Key Duties and Responsibilities

• Culture human stem cells in 2D and/or 3D
• Completes experiments in a reliable, consistent manner
• Demonstrates a high level of attention to detail and follows SOP strictly
• Performs initial analysis of experimental data and interprets immediate experimental outcomes
• Records experiments and results in laboratory notebooks (including all electronic systems) in accordance with lab procedures
• Recognizes problems and suggests experiments to troubleshoot issues
• Develops new ideas to improve workflows, consistency and efficiency of the cell culture processes
• Clearly and effectively communicates (both written and verbal) results

Knowledge and Skills

• Experience with advanced human cell culture techniques
• Teachable mindset capable of learning protocols to execute stem cell differentiations producing consistent high-quality product
• Ability and willingness to work rotating weekend shifts according to business needs
• Adaptive to a time-line driven work environment
• Multitasking skills, attention to details and ability to work in a collaborative team environment
• Work with cross-functional teams to plan, coordinate, and execute experiments.
• Great interpersonal/teamwork skills and positive attitude
• Proven technical proficiency and demonstrated skill in conducting and interpreting experiments including the development of human stem cell models and assays to evaluate targets and lead molecules for Vertex diseases.
• Uses technical knowledge to design and execute follow-up experiments

Education and Experience

Masters Degree (or equivalent degree) in biological sciences and 0-2 years of relevant employment experience, or Bachelors Degree (or equivalent degree) in biological sciences and 4+ years of relevant employment experience

Pay

Pay Range: $74,800 - $112,200

Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

Flex Designation

On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law.

Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]

Benefits

From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Help Us Achieve Our Mission

Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.