Stem Cell Senior Research Associate

Vertex Pharmaceuticals Incorporated; Boston (MA); On-site; USD 75,000 - 112,000; Full time

Job summary

Vertex Pharmaceuticals Incorporated in Boston seeks a cell culture specialist to help coordinate production of program-relevant cell types, including stem cell-derived islets, for research projects. You will culture in 2D and 3D and differentiate cells for in vitro and in vivo studies.

The role requires meticulous lab practices, adherence to SOPs, and effective communication of results. Weekend shifts may be required in a timeline-driven, collaborative environment.

Qualifications

• Masters degree (or equivalent) in biological sciences with 0-2 years of relevant employment experience, or
• Bachelor's (or equivalent) in biological sciences with 4+ years of relevant employment experience
• Experience with human stem cell culture and differentiation
• Ability to work rotating weekend shifts and adapt to a timeline-driven environment

Responsibilities

• Culture human stem cells in 2D and/or 3D
• Complete experiments reliably and consistently
• Follow SOPs strictly and maintain detailed lab notebooks
• Analyze experimental data and interpret outcomes
• Communicate results clearly in writing and verbally
• Collaborate with cross-functional teams to plan and execute experiments
• Develop ideas to improve workflows and efficiency
• Contribute to development of human stem cell models and assays

Skills

Advanced human cell culture

Stem cell differentiation

Team collaboration

Weekend shifts

Data analysis

Experiment design

Cross-functional teams

Communication skills

Protocol adherence

Education

Masters degree in biological sciences

Bachelor's degree in biological sciences with 4+ years experience

Job description

Job Description

General Summary

The successful candidate will work in a team setting and be responsible for coordinating production of program-relevant cell types such as stem cell-derived islets (SC-islet) for use across research team projects. This includes 2D and 3D culture of pluripotent stem cells as well as differentiation for in vitro and in vivo studies. A demonstrated strong understanding of best lab practices to ensure reliability, consistency, efficiency, and quality control, as well as dedication to lab bench work, are required.

Key Duties and Responsibilities

• Culture human stem cells in 2D and/or 3D
• Completes experiments in a reliable, consistent manner
• Demonstrates a high level of attention to detailand follows SOP strictly
• Performs initial analysis of experimental data and interprets immediate experimental outcomes
• Records experiments and results in laboratory notebooks (including all electronic systems) in accordance with lab procedures
• Recognizes problems and suggests experiments to troubleshoot issues
• Develops new ideas to improve workflows, consistency and efficiency of the cell culture processes
• Clearly and effectively communicates (both written and verbal) results

Knowledge and Skills

• Experience with advanced human cell culture techniques
• Teachable mindset capable of learning protocols to execute stem cell differentiations producing consistent high-quality product
• Ability and willingness to work rotating weekend shifts according to business needs
• Adaptive to a time-line driven work environment
• Multitasking skills, attention to details and ability to work in a collaborative team environment
• Work with cross-functional teams to plan, coordinate, and execute experiments.
• Great interpersonal/teamwork skills and positive attitude
• Proven technical prociency and demonstrated skill in conducting and interpreting experiments including the development of human stem cell models and assays to evaluate targets and lead molecules for Vertex diseases.
• Uses technical knowledge to design and execute follow-up experiments

Education and Experience

• Masters Degree (or equivalent degree) in biological sciences and 0-2 years of relevant employment experience, or
• Bachelors Degree (or equivalent degree) in biological sciences and 4+ years of relevant employment experience

Pay Range

$74,800 - $112,200

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

On-Site Designated

Flex Eligibility Status

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]