Stem Cell Islet Therapeutics Scientist

Biopharma Careers; Boston (MA); On-site; USD 104,000 - 156,000; Full time

Job summary

Vertex is seeking a Stem Cell Research Scientist to advance cell-based therapies for type 1 diabetes. The role focuses on pluripotent stem cell culture, islet differentiation, and translational research with rigorous experimental design.

You will design complex in vitro and ex vivo studies, develop assays, and collaborate across teams to drive preclinical objectives. The position is on-site in our research facilities with comprehensive benefits.

Qualifications

• Ph.D. or equivalent in molecular and cell biology, developmental biology, stem cell biology, or related field with 0–3 years of postdoctoral experience; or
• Master's degree in molecular and cell biology with 3+ years of experience; or
• Bachelor's degree with 6+ years of experience in related discipline.

Responsibilities

• Design, execute, and analyze in vitro and ex vivo experiments using primary islets and stem cell-derived islet models.
• Develop and optimize in vitro assays for phenotypic and physiological characterization of islet biology.
• Execute extended stem cell differentiation campaigns, including maintenance, expansion, and differentiation of pluripotent stem cells.
• Apply molecular, cellular, and biochemical techniques to characterize stem cell-derived models and assess outcomes.
• Collaborate with internal research teams to support translational and preclinical objectives.
• Maintain accurate experimental records and contribute to scientific reports and documentation.
• Interpret complex biological datasets and recommend next steps.
• Stay current with advances in stem cell biology and diabetes research.
• Support troubleshooting and protocol refinement for lab processes.
• Contribute to a collaborative and rigorous team environment.

Skills

Stem cell biology

Pluripotent stem cells

Experimental design

Data analysis

Scientific communication

Education

Ph.D. in molecular and cell biology

Master's in molecular and cell biology

Bachelor's in molecular and cell biology

Tools

scRNA-seq

Flow cytometry

Western blotting

Immunohistochemistry

Job description

Vertex is seeking a Stem Cell Research Scientist to advance cell-based therapies for type 1 diabetes. The role focuses on pluripotent stem cell culture, islet differentiation, and translational research with rigorous experimental design.

You will design complex in vitro and ex vivo studies, develop assays, and collaborate across teams to drive preclinical objectives. The position is on-site in our research facilities with comprehensive benefits.