Statistical/Population Geneticist — Immunology Research

Scorpion Therapeutics; Boston (MA); On-site; USD 180,000 - 280,000; Full time

Job summary

Scorpion Therapeutics in Boston seeks a senior geneticist focused on population genetics and causal inference to accelerate autoimmune drug discovery. You will lead analyses that connect genetic variation to disease mechanisms and translate findings into therapeutic strategies.

The role requires handling large-scale datasets, applying Mendelian randomization, and collaborating across biology, chemistry, and engineering to prioritize targets and de-risk programs.

Qualifications

• PhD in genetic epidemiology, statistical genetics, or related field.
• Experience with large-scale human genetic datasets, Mendelian randomization, and causal inference techniques.
• Proficiency in R, Git, and genotype data tools.

Responsibilities

• Lead systematic reviews of genetic evidence for immunology targets and apply Mendelian randomization and causal methods to large datasets.
• Interpret GWAS, exome/genome sequencing, and multi-omics data to prioritize and de-risk therapeutic targets.

Skills

Mendelian randomization

Causal inference

Large-scale genetic datasets

Statistical genetics

Education

PhD in genetic epidemiology or statistical genetics

Tools

R

Git

Genotype data tools

Job description

Role

Senior geneticist specializing in population genetics and causal inference within immunology drug discovery, focusing on autoimmune diseases.

Responsibilities

• lead systematic reviews of genetic evidence for immunology targets, apply Mendelian randomization and other causal methods to large datasets (e.g., UK Biobank, AllofUs), interpret GWAS, exome/genome sequencing, and multi-omic data to prioritize and de-risk therapeutic targets, and collaborate cross-functionally to translate findings into drug development strategies.

Requirements

• Ph.D. in genetic epidemiology, statistical genetics, or related field; extensive experience with large-scale human genetic datasets, Mendelian randomization, and causal inference techniques; proficiency in R, Git, and genotype data tools.

Preferred

• experience with fine-mapping, colocalization, immune genetics, multi-omics integration, and external collaborations.

High-Value

focus on immunology (rheumatology, gastroenterology, dermatology), autoimmune indications, early target evaluation, and genetic evidence assessment for drug discovery.

Work setup

roles based in Indianapolis or Boston, with a focus on collaborative multi-disciplinary engagement to support target prioritization decisions.