Staff Systems Engineer for AI-Driven Biotech Platforms

Phylo; South San Francisco (CA); On-site; USD 200,000 - 300,000; Full time

Benefits offered by this job

Competitive salary and equity

Full medical, dental, and vision coverage

401(k) plan

Unlimited PTO

Free lunch and snacks

Regular team offsites

Culture of excellence and speed

Job summary

Phylo, based in South San Francisco, is seeking an experienced engineer to build and operate the core systems of its agentic AI platform. You will design distributed systems, ensure reliable infrastructure, and partner with teams to enhance workflows. The ideal candidate has over 3 years of experience in distributed systems and strong skills in programming, Kubernetes, and cloud environments. The role offers a competitive salary between $200K and $300K, full medical benefits, unlimited PTO, and an engaging company culture.

Qualifications

• 3+ years of industry experience in backend, infrastructure, or distributed systems engineering.
• Strong proficiency in at least one programming language (e.g., Python, Go, Rust, or similar).
• Experience designing and operating distributed systems in production.
• Deep hands-on experience with containerization and Kubernetes.
• Experience with infrastructure-as-code tooling.
• Experience operating systems on at least one major cloud provider.
• Comfort owning systems end-to-end in fast-moving environments.

Responsibilities

• Design and build production systems that orchestrate agent execution.
• Build and operate scalable, reliable infrastructure across environments.
• Develop systems for secure task isolation and compliance foundations.
• Partner closely with ML and science teams for robust distributed systems.

Skills

Backend engineering

Distributed systems

Containerization

Kubernetes

Infrastructure as code

Python

Cloud computing

Tools

Terraform

AWS

GCP

Azure

Job description

Phylo, based in South San Francisco, is seeking an experienced engineer to build and operate the core systems of its agentic AI platform. You will design distributed systems, ensure reliable infrastructure, and partner with teams to enhance workflows. The ideal candidate has over 3 years of experience in distributed systems and strong skills in programming, Kubernetes, and cloud environments. The role offers a competitive salary between $200K and $300K, full medical benefits, unlimited PTO, and an engaging company culture.