Staff Scientist - Gastroenterology (Hepatology)

Washington University

Northern (KY)

Hybrid

USD 48,000 - 87,000

Full time

14 days+

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Job summary

Washington University, located in Saint Louis, MO, seeks motivated scientists to join an interdisciplinary HBV research program focusing on viral persistence and potential cures. The Schwartz Laboratory emphasizes human models of infection using stem cell-derived hepatocytes and CRISPR/Cas9 editing to study host-virus interactions.

The role involves designing protocols, data management, and assisting with grants while conducting complex data analyses and preparing publications.

Qualifications

Education: Master’s degree or combination of education and/or experience may substitute for minimum education.
Work Experience: Laboratory Operations (3 Years)
Certifications/Professional Licenses: No specific certification/professional license required for this position.
Driver's License: A driver's license is not required for this position.

Responsibilities

Designs research protocols following discussions with the PI and develops data collection procedures.
Assists with grant preparation and reporting.
Performs complex statistical analysis of data and writes interpretive reports.
Verifies data correctness and makes recommendations based on analyses.
Documents research topics and prepares papers for publication or presentation.
Conducts literature searches related to the project.
Performs other duties as assigned.

Education

Master’s degree

Ph.D.

Job description

Location

SAINT LOUIS, MO 63110

Scheduled Hours 40

Position Summary

The Schwartz Laboratory in the Division of Gastroenterology, Department of Medicine, at WashU Medicine in St. Louis is seeking motivated and creative scientists to join our interdisciplinary research program investigating the biology of hepatitis B virus (HBV) and the mechanisms that allow the virus to establish and maintain chronic infection.

Our long-term goal is to understand the complex interactions between HBV and its host that drive viral persistence and to use these insights to identify new strategies toward a functional cure for chronic hepatitis B, which remains a major global health challenge and an important cause of liver related morbidity and mortality.

Our laboratory has a strong history of developing innovative human models of viral infection. We were among the first groups to establish hepatitis B and hepatitis C virus infection models using stem cell-derived hepatocytes, and we have continued to combine these systems with primary human hepatocytes, CRISPR/Cas9 gene editing, and genetically distinct HBV clones to dissect the host and viral factors that determine infection and persistence.

Recent work from the laboratory, published in Cell, identified a nucleosome-level molecular switch that primes and influences HBV infection (10.1016/j.cell.2025.01.033).

Job Description

Primary Duties & Responsibilities: Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.

Assists with grant preparation and reporting.

Performs complex statistical analysis of data collected and writes interpretative reports.

Verifies the correctness of the data submitted and makes recommendations based on these analyses.

Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.

Solves practical problems relating to difficulties with equipment or test subjects.

Suggests technical or procedural improvements in testing methods.

Conducts literature searches related to research project.

Performs other duties as assigned.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Required Qualifications

Education: Master’s degree or combination of education and/or experience may substitute for minimum education.
Certifications/Professional Licenses: No specific certification/professional license is required for this position.
Work Experience: Laboratory Operations (3 Years)
Skills: Not Applicable
Driver's License: A driver's license is not required for this position.

Preferred Qualifications

Education: Ph.D.
Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience: No additional work experience unless stated elsewhere in the job posting.
Skills: Analytical Problem Solving, Communication, Computer Literacy, Data Analysis, Data Interpretations

Grade R10 Salary Range

$48,000.00 - $86,900.00 / Annually

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Personal up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family: We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University's policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Company Culture

Washington University in St. Louis' collective success is significantly attributed to the passion and outstanding efforts of our community. Our staff, faculty and trainees are committed to excellence and dedicated to carrying out our missions of research, teaching and patient care.

WashU prides itself on being a place where people matter, and serious work is done. Our people work together in an inclusive community that celebrates diverse perspectives, collaboration and innovation. We are a community of individuals inspired to work together to develop big ideas and tackle challenging problems. We value the well-being of our people. WashU strives to create a positive employee experience where staff, faculty and trainees thrive, both personally and professionally. Our employees find meaning, connection and vitality in their work and life with a healthy work-life balance and support to learn, grow and make an impact at WashU, the community and the world.

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