Staff Scientist: Electrophysiology & Optogenetic Tools

Baylor College of Medicine (BCM); Houston (TX); On-site; USD 90,000 - 130,000; Full time

Job summary

Baylor College of Medicine’s St-Pierre lab seeks a Staff Scientist to lead techniques for voltage indicators and optogenetic silencers in vivo/in vitro, using electrophysiology and multi-photon imaging. You will contribute to protein engineering, data analysis, and manuscript preparation in a fast-paced neurobiological research setting.

The role emphasizes hands-on experimental design, collaboration, and dissemination of findings at conferences, with opportunities to develop skills in two-photon

Qualifications

• Doctoral Degree; no substitution.
• Three years of postdoctoral research experience.

Responsibilities

• Designs and conducts experiments combining electrophysiology with optogenetic activation or optical imaging to characterize GEVIs and optogenetic silencers in vitro and in vivo.
• Analyzes electrophysiology and imaging data using commercial software or customized data pipelines.
• Cultures mammalian cells; prepares brain slices and/or dissociated neurons; maintains and troubleshoots the electrophysiological rig and related reagent/tool supply.
• Reviews literature on voltage indicators, optogenetic silencers, and related protein engineering approaches to inform experimental design.
• Communicates research results in group meetings and at national or international conferences.
• Teaches techniques, procedures, and experimental design to other members of the lab.
• Characterizes and applies new light-responsive proteins in vitro and in vivo.
• Contributes to protein engineering efforts to improve sensor/actuator performance.
• Operates and maintains two-photon voltage imaging equipment.
• Contributes to manuscript and grant report preparation.
• Maintains lab notebooks and data records per lab and institutional standards.

Skills

Experimental design

Data analysis

Scientific communication

Collaboration

Education

Doctoral degree

Tools

Two-photon imaging

Electrophysiology

Molecular cloning

Mammalian cell culture

Job description

Baylor College of Medicine’s St-Pierre lab seeks a Staff Scientist to lead techniques for voltage indicators and optogenetic silencers in vivo/in vitro, using electrophysiology and multi-photon imaging. You will contribute to protein engineering, data analysis, and manuscript preparation in a fast-paced neurobiological research setting.

The role emphasizes hands-on experimental design, collaboration, and dissemination of findings at conferences, with opportunities to develop skills in two-photon