Staff Data Scientist San Francisco, California

HeartFlow, Inc.; San Francisco (CA); On-site; USD 220,000 - 280,000; Full time

Job summary

HeartFlow is seeking a senior data science leader to drive data analysis, annotation, and data campaigns for AI model improvements. You will guide cross‑functional teams and shape data requirements for end‑point objectives.

The role focuses on advanced data curation, MLOps collaboration, and rigorous performance evaluation across diverse patient data, with a strong emphasis on medical imaging and vascular CT data.

Qualifications

• Masters or PhD in Engineering, CS, Statistics, or Data Science.
• Seven plus years in Data Science / ML / CV in industry or five+ with PhD.
• Experience with medical imaging data is highly preferred.
• Proficient in Python with scipy, sklearn, statsmodels.
• Familiarity with 3D processing tools (VTK/ITK) and visualization (3DSlicer/MITK).
• Experience with data lakes, SQL/NoSQL, AWS, Tableau.

Responsibilities

• Lead data analysis, curation, and annotation to improve AI models.
• Design data campaigns and annotation strategies for large-scale campaigns.
• Architect data management with MLOps and dashboards for monitoring.
• Develop evaluation tools and statistical analyses across datasets.

Skills

Data science

Machine learning

Computer vision

Medical imaging

Statistical analysis

Communication

Education

Masters or PhD in Engineering/CS/Statistics/Data Science

Tools

Python

scikit-learn

scipy

statsmodels

seaborn

VTK

ITK

3DSlicer

MITK

SQL

NoSQL

AWS

Tableau

Job description

Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting‑edge technology. The flagship product—an AI‑driven, non‑invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFR CT Analysis—provides a color‑coded, 3‑D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI‑driven non‑invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap Analysis), assess coronary blood flow (FFR CT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.

Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide.

Job Responsibilities

• Vision & Cross‑Functional Leadership: Engage with cross‑functional teams (Product, Research, Engineering, and Process Engineering) and help guide the overarching vision for data analysis, curation, and annotation to improve our AI models. Drive the definition of algorithm and data requirements necessary to deliver on end‑point objectives.
• Data Campaigns and Annotation Strategy: Introduce best practices and efficient processes to enable multiple, large‑scale annotation campaigns for continuous AI product improvements. Spearhead the strategic design of data campaigns needed to advance AI algorithms.
• Advanced Data Curation & Management: Develop comprehensive data curation strategies for improvements to AI models. Partner with MLOps to architect data management systems for algorithm training and performance validation, and establish data dashboards and monitoring reports.
• Performance Evaluation and Statistical Analysis: Establish frameworks and develop tools to rigorously evaluate the strengths and weaknesses of model iterations across patient populations. Design and oversee data analyses using statistical techniques to illuminate the performance of our AI algorithms.

Required Qualifications

• Education: Masters or PhD Degree in Engineering, Computer Science, Statistics, Data Science or related degree.
• Work Experience: 7+ years (or 5+ with PhD) of proven track record in Data Science, Machine Learning, Computer Vision, or Image Analysis in industry. Have experience working on complex, real‑world AI problems in medical imaging or computer vision requiring careful consideration of data needs.
• Software: Proficient in Python, including statistical and machine‑learning packages (e.g. scipy, sklearn, statsmodels, seaborn) with a commitment to writing clean, reproducible and scalable code. Familiarity with image and 3‑D processing tools like VTK and ITK, and visualization tools like 3DSlicer and MITK is a plus.
• Statistics: Understanding of standard statistical techniques and ability to apply appropriate statistical methods to a range of data structures; experience with medical imaging data a plus.
• Data Management: Experience working with data lakes, SQL/NoSQL Databases, AWS Cloud Storage, Tableau dashboards.
• AI & Medical Imaging: Expertise in deep learning and machine‑learning models in production. Strong experience working with medical imaging data (CT and vascular imaging) is highly preferred.
• (Preferred) Proficiency in Agentic AI Tools: Experience integrating generative AI and agentic tools into daily workflows to act as a force multiplier—accelerating coding, prototyping, and complex data analysis—while demonstrating the critical judgment required to rigorously evaluate AI outputs for accuracy.
• Communication: Excellent written and verbal communication. Detail orientated but able to describe complex topics in a manner that is digestible to a broad audience. Ability to distill complex analyses into interpretable and actionable findings.
• Commitment: Committed to the success of the team and successful completion of project – 75% confidence / 100% committed.
• Influence without Authority: Able to build trust and obtain cross‑functional alignment across departments.

Salary: $220,000 to $280,000, bonus, and equity. #LI-IB1 #LI-Hybrid

Equal Opportunity Employer

Heartflow is an Equal Opportunity Employer. We are committed to a work environment that supports, inspires, and respects all individuals and do not discriminate against any employee or applicant because of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. This policy applies to every aspect of employment at Heartflow, including recruitment, hiring, training, relocation, promotion, and termination.