Staff Bioinformatics Scientist - Signal Processing

Illumina, Inc.; San Diego (CA); On-site; USD 156,000 - 233,000; Full time

Benefits offered by this job

Genomics sequencing access

Family planning benefits

Health/dental/vision insurance

Retirement benefits

Paid time off

Job summary

Illumina, Inc. in the United States seeks a Staff Bioinformatics Scientist – Signal Processing to design and implement signal processing and bioinformatics algorithms for genomic data. You will analyze data, optimize software, and collaborate with external teams to ensure end-to-end workflows.

The role emphasizes C/C++ development on Linux for multi-threaded applications, with opportunities for technical leadership and cross-functional collaboration across projects and executives.

Qualifications

• Master’s degree or PhD in bioinformatics, biology, engineering, physical sciences, computer science, mathematics, statistics, or equivalent.
• Minimum 6 years of related experience with a Master’s degree.
• Experience with signal processing, data analysis, and the application of statistical approaches.
• Experience with C++ is preferred, but other languages (e.g., Java or C#) will be considered.

Responsibilities

• Design, prototype, and implement signal processing and bioinformatics algorithms.
• Analyze data and optimize software at the algorithm, design, and/or source code level.
• Collaborate with external teams to ensure a smooth, end-to-end workflow with external organizations.
• Develop, debug, and integrate optimized C/C++ software on Linux for multi-threaded applications.
• Provide technical leadership and represent the team at project and executive levels.

Skills

Signal processing

Data analysis

C++

Object‑oriented design

Problem solving

Teamwork

Communication

Python

Education

Master’s degree or PhD in bioinformatics, biology, engineering, physical sciences, computer science, mathematics, statistics, or equivalent

Tools

Linux

Git

Python

C++

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life‑changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world‑changing projects, you will do more and become more than you ever thought possible.

What if the work you did everyday could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life‑changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, can make a difference. Surrounded by extraordinary people, inspiring leaders, and world‑changing projects, you will do more and become more than you ever thought possible.

Illumina’s Primary Analysis team specializes in designing algorithms and developing software to detect genomic data from signals contained within images. Algorithmic challenges in this area include compensating for signal impairments introduced by optical, chemical, and mechanical systems. Implementation challenges include managing parallel tasks, optimizing memory accesses, and improving the speed and accuracy of genomic base calling. We develop methods to address these challenges by focusing on high reliability, speed, and completeness of results. We are seeking an exceptional individual to join our team in developing analysis solutions for use by researchers and clinicians worldwide.

Responsibilities:

• Design, prototype, and implement signal processing and bioinformatics algorithms
• Analyze data and optimize software at the algorithm, design, and/or source code level
• Collaborate with external teams to ensure a smooth, end-to-end workflow with external organizations
• Develop, debug, and integrate optimized C/C++ software on Linux for multi-threaded applications
• Provide technical leadership and represent the team at project and executive levels

Requirements:

• Experience with signal processing, data analysis, and the application of statistical approaches
• Experience with C++ is preferred, but other languages (e.g., Java or C#) will also be considered (Minimum: intermediate level with understanding of object‑oriented design)
• Ability to define the architecture, develop, and debug software applications
• Strong problem‑solving skillsil>
• Personal initiative and ability to work effectively as part of a team
• Superior written and verbal communication skills
• Be curious, detail oriented, and analytical, with a proven ability to learn quickly

Desired:

• Experience with communications theory and information theory
• Experience with time‑series analysis and interpretation of temporal data
• Experience with Python and Python visualization libraries
• Experience with multi‑threaded software, real‑time systems, and/or software acceleration
• Familiarity with Agile software development processes (e.g. Scrum)
• Experience with using version control systems such as Git

Education & Experience:

• Master’s degree or PhD in bioinformatics, biology, engineering, physical sciences, computer science, mathematics, statistics, or equivalent
• Minimum 6 years of related experience with a Master’s degree

The estimated base salary range for the Staff Bioinformatics Scientist -- Signal Processing role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package.

We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We’re a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission.

Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics.

We are proud to confirm a zero‑net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process.

If you require accommodation to complete the application or interview process, please contact [e-mail].

To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.