Staff Associate II in Translational Biomedical Research

Columbia University; New York (NY); On-site; USD 90,000 - 120,000; Full time

Job summary

Columbia University in the City of New York is seeking a Staff Associate II to conduct translational biomedical research using genetically engineered mouse models, organoids, histology, and omics analyses. The role includes performing and analyzing experiments, troubleshooting, interpreting data, and optimizing protocols.

You will support project management and inter-laboratory collaborations, applying scientific judgment to advance research projects and contribute to team objectives.

Qualifications

• Bachelor's degree required.
• Experience with mouse models, organoid culture, molecular and histologic analyses.
• Strong communication and collaboration skills in research settings.

Responsibilities

• Conduct translational biomedical research using mouse models, organoids, histology and omics analyses.
• Perform and analyze experiments, troubleshoot technical challenges and optimize protocols.
• Support project management and inter-lab collaborations with scientific judgment.

Skills

Scientific communication

Organizational skills

Collaborative research

Teaching or mentoring

Education

Bachelor's degree

Job description

The primary function of this position is to conduct translational biomedical research using genetically engineered mouse models, organoid cultures, histology, and omics analyses. Responsibilities include performing and analyzing experiments, troubleshooting technical challenges, interpreting data, and optimizing research protocols. The Staff Associate II will also support project management and inter-laboratory collaborations, applying scientific judgment and technical expertise to advance research projects.

Responsibilities

Functional Knowledge

• Apply knowledge of regenerative medicine, in vitro organoid and in vivo animal models for translational studies. Integrate experimental findings for mechanistic discoveries and therapeutic evaluations (20%)

Problem Solving

• Troubleshoot and optimize organoid cultures, tissue processing, histologic assays, and related experimental protocols in moderately complex situations. Analyze experimental results to identify technical limitations and recommend protocol modifications or follow-up experiments (20%)

Decision Making/Autonomy

• Conduct assigned research activities independently and collaboratively, including planning experimental workflows, selecting appropriate controls, and adapting protocols based on experimental outcomes. Exercise scientific judgment in prioritizing experiments and coordinating interconnected organoid, animal, and tissuebased studies (20%)

Technical Expertise

• Perform organoid culture, animal tissue collection, histologic processing and examination, IHC/IF, molecular assays, and quantitative and omics-based analyses. Develop and optimize experimental methods for disease modeling, drug screening, and evaluation of therapeutic responses (20%)

Communication

• Summarizes and explains experimental procedures and findings to the PI and research team. Coordinate experimental activities, data, and protocols with collaborating laboratories (20%)

Qualifications

• Bachelor's degree
• 4 years of experience is recommended
• Experience with mouse models, cell and organoid culture, molecular and histologic analyses, and interpretation of experimental data.
• Strong scientific communication and organizational skills, including experience with research presentations, teaching or mentoring, and collaborative research.

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