Sr Systems Engineer

Uncover; Wilsonville, Northern (OR, KY); Hybrid; USD 120,000 - 180,000; Full time

Job summary

Twist Bioscience seeks a Senior Systems Engineer to join our team onsite in Wilsonville, OR. You will work with bioprocess automation, develop and test protocols, and maintain instruments in a fast-paced lab environment connected to LIMS systems.

Ideal candidates have a PhD or MS with 3+ years (BS with 5+ years) in related engineering fields, strong scripting skills (C#, Python), and experience with lab automation interfaces like MES/Maestro or Twist.

Qualifications

• PhD or MS with 3 years, BS with 5 years in Biomedical/Chemical/Mechanical/Electrical Eng or related field.
• Experience in automated instrumentation for bioprocesses.
• Experience with DoE for testing and troubleshooting.
• Experience scripting in C# or Python in lab automation systems.
• Experience with interfaces between robotic instrumentation and LIMS systems (MES/Maestro, Twist).
• Strong data analysis and scientific computing skills.

Responsibilities

• Develop, validate, and release new processes and technologies for cost-effectiveness and quality.
• Develop and test protocols, scripts, and systems to automate bioprocesses.
• Operate and maintain lab automation equipment and cross‑integration systems.
• Collaborate with multi-disciplinary teams to troubleshoot equipment and systems.
• Prepare documentation, knowledge transfer, and training materials.
• Ensure compliance with regulatory and ISO 13485 requirements.

Skills

Automation scripting

DoE methods

Data analysis

Hardware assembly

Team collaboration

Scientific computing

Education

Ph.D. or MS with 3+ years, BS with 5 years in related field

Tools

C#

Python

Maestro/LIMS interfaces

Twist integration

Robot instrumentation

Job description

Sr. Systems Engineer (Onsite in Wilsonville, OR) Summary We are seeking a Senior Systems Engineer to join our team in Portland, OR (PDX).

What You’ll Do

• Develop, validate, and release new processes and technologies to achieve cost-effectiveness and improved product quality
• Develop and test protocols, scripts, and systems to automate certain bioprocesses
• Operation and maintenance of a range of scientific instruments and tools with a focus on laboratory automation systems and cross-integration systems
• Collaborate with multi-disciplinary teams in troubleshooting and resolving issues concerning equipment and systems
• Prepare and participate in documentation, knowledge transfer, and training activities
• Follow regulatory and ISO 13485 requirements

What You’ll Bring

• Ph.D. or MS with 3 years, BS with 5 years of related experience in Biomedical Engineering, Chemical Engineering, Mechanical/Electrical Engineering, or related field
• Experience in developing automated instrumentation for bioprocesses
• Experience with DoE for testing and troubleshooting of certain processes
• Experience in designing and writing scripts (C#, Python, etc) using control software or dynamic scheduling software native to laboratory automation systems and cross-integration systems
• Experience with sample tracking software and developed interfaces between robotic instrumentation and LIMS systems (MES/Maestro, Twist build)
• Excellent scientific computation and data analysis capabilities
• Hands‑on skills to assemble and maintain hardware
• Experience with biological instrumentation for liquid transfer, PCR, cell‑based cloning, DNA extraction, and purification is desirable
• Working collaboratively with other functional groups
• Excellent communication and writing skills, and ability to work in a fast‑paced team environment

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.