Sr Staff Architect, Software (SQL Database)

ThermoFisher Scientific; Greenville (NC); On-site; USD 136,000 - 204,000; Full time

Benefits offered by this job

Health insurance

Dental plans

Vision plan

Employee assistance programs

Tuition reimbursement

Paid time off

Job summary

Thermo Fisher Scientific is seeking a Sr Staff Architect (SQL Database) to design secure, scalable healthcare SaaS databases handling PHI/PII with HIPAA/HITECH compliance. You will architect multi-tenant data platforms, encryption, and governance for real-time access and high availability.

You will collaborate with security, compliance, and engineering teams, lead data migrations with EHR/EMR integrations, and guide CI/CD practices for database changes in a regulated environment.

Qualifications

• Bachelor’s or Master’s degree in Computer Science, Information Systems, or related field
• 10+ years of progressive industry experience in enterprise technology, architecture, and systems management.
• 7+ years of experience in database architecture, preferably in SaaS environments
• Prior experience building data pipelines using SSIS, Azure Data Factory or similar
• Strong experience with data lake architectures (AWS S3, Azure Data Lake, Google Cloud Storage)
• Proven experience designing or managing data farm / distributed data platforms (Hadoop, Spark, Databricks)
• Hands‑on experience handling sensitive data (PHI, PII/PPI) in regulated environments
• Strong knowledge of HIPAA compliance, data privacy, and security frameworks
• Expertise in relational databases (PostgreSQL, MySQL, SQL Server) and non‑relational systems such as Cosmos DB, MongoDB
• Experience with cloud platforms (AWS, Azure, GCP), especially healthcare-compliant services
• Proficiency in data encryption, key management, and RBAC
• Strong understanding of scaling strategies and distributed systems
• Must be legally authorized to work in the United States without sponsorship.
• Must be able to pass a comprehensive background check, which includes a drug screening.

Responsibilities

• Design and implement secure, scalable, multi-tenant database architectures for healthcare SaaS applications
• Develop data models and storage solutions for sensitive healthcare data (PHI, PII/PPI)
• Ensure compliance with HIPAA, HITECH, GDPR, and other relevant regulations
• Implement data encryption (at rest and in transit), masking, and access controls
• Architect systems for high availability, disaster recovery, and auditability
• Define and enforce data governance, retention, and audit logging policies
• Optimize database performance for large-scale healthcare datasets and real-time access
• Collaborate with security, compliance, and engineering teams to meet regulatory requirements
• Lead data migration and integration with EHR/EMR systems and third-party healthcare platforms
• Comply best practices for secure CI/CD pipelines involving database changes
• Monitor systems for data integrity, breaches, and anomalous access patterns

Skills

Data pipeline design

HIPAA compliance

Cloud platforms

RBAC

Encryption

Multi-tenant architectures

Data governance

Handling sensitive data

Education

Bachelor’s or Master’s degree

Tools

SSIS

Azure Data Factory

AWS

Azure

GCP

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Job Summary

We are seeking a Sr Staff Architect (SQL Database) to design and manage secure, scalable, and compliant database systems for our healthcare SaaS platform. This role requires expertise in handling sensitive data, including PII/PPI and PHI, while ensuring compliance with healthcare regulations and delivering high-performance, multi-tenant solutions.

Key Responsibilities

• Design and implement secure, scalable, multi-tenant database architectures for healthcare SaaS applications

• Develop data models and storage solutions for sensitive healthcare data (PHI, PII/PPI)

• Ensure compliance with HIPAA, HITECH, GDPR, and other relevant regulations

• Implement data encryption (at rest and in transit), masking, and access controls

• Architect systems for high availability, disaster recovery, and auditability

• Define and enforce data governance, retention, and audit logging policies

• Optimize database performance for large-scale healthcare datasets and real-time access

• Collaborate with security, compliance, and engineering teams to meet regulatory requirements

• Lead data migration and integration with EHR/EMR systems and third-party healthcare platforms

• Comply best practices for secure CI/CD pipelines involving database changes

• Monitor systems for data integrity, breaches, and anomalous access patterns

Required Qualifications

• Bachelor’s or Master's degree in Computer Science, Information Systems, or related field

• 10+ years of progressive industry experience in enterprise technology, architecture, and systems management.

• 7+ years of experience in database architecture, preferably in SaaS environments

• Prior experience building data pipelines using SSIS, Azure Data Factory or similar

• Strong experience with data lake architectures (e.g., AWS S3, Azure Data Lake, Google Cloud Storage)

• Proven experience designing or managing data farm / distributed data platforms (e.g., Hadoop, Spark, Databricks ecosystems)

• Hands‑on experience handling sensitive data (PHI, PII/PPI) in regulated environments

• Strong knowledge of HIPAA compliance, data privacy, and security frameworks

• Expertise in relational databases (PostgreSQL, MySQL, SQL Server) and non‑relational systems such as Cosmos DB, MongoDB

• Experience with cloud platforms (AWS, Azure, GCP), especially healthcare-compliant services

• Proficiency in data encryption, key management, and role-based access control (RBAC)

• Strong understanding of scaling strategies and distributed systems

• Must be legally authorized to work in the United States without sponsorship.

• Must be able to pass a comprehensive background check, which includes a drug screening.

Preferred Qualifications

• Experience working with EHR/EMR systems (e.g., Epic, Cerner) or healthcare integrations (HL7, FHIR)

• Familiarity with healthcare data standards and interoperability frameworks

• Experience with audit logging, compliance reporting, and risk assessments

• Certifications such as AWS Certified Security Specialty, Certified HIPAA Professional (CHP)

• Experience with containerization (Docker, Kubernetes)

Compensation and Benefits

The salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs

• Employee assistance and family support programs, including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.