Sr Scientist I, Biologics Purification and Characterization

AbbVie Inc; North Chicago (IL); On-site; USD 80,000 - 120,000; Full time

Job summary

AbbVie Inc is seeking a highly motivated scientist to enhance biologics drug discovery efforts. This role focuses on purification techniques and method development, demanding a strong educational background and experience in process development. Join a collaborative team to drive innovations in therapeutic solutions.

Benefits

Paid time off

Medical/Dental/Vision insurance

401(k) plan

Short-term incentive programs

Qualifications

• Bachelor’s or Master’s Degree typically requires 8-10 years of experience.
• PhD candidates considered with no required experience.
• Proficient in chromatography techniques and software.

Responsibilities

• Purify bispecific candidates and support drug-like property assays.
• Design and execute process development strategies.
• Conduct analytical characterization and develop methods for impurities.

Skills

Analytical characterization

Problem solving

Communication

Education

Bachelor’s Degree

Master’s Degree

PhD

Tools

Chromatography software

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn, and TikTok.

Job Description

The Biologics Discovery Sciences group at AbbVie is seeking a highly motivated scientist to join a dynamic core team supporting biologics drug discovery. The role will focus on purifying bispecific candidates with suitable purity and characteristics to support advancement into in vitro (drug-like property assays, binding, cell-based assays) and in vivo studies (efficacy, non-GLP NHP PK, DRF). The applicant must be proficient in standard bioprocess and chromatography techniques at large scale (1g-200g). Responsibilities include designing and executing process development strategies to address production liabilities and future scalability. The candidate should be an independent, creative problem solver experienced in overcoming issues related to solubility, aggregation, recovery, and purity during purification. The role also involves analytical characterization of molecules and development of analytical methods to characterize impurities. A thorough understanding of how molecular and post-translational attributes of bispecifics influence their function is essential.

The candidate should be able to work independently using chromatography software such as Unicorn, Chromeleon, and Empower. Keeping current with scientific literature and applying new knowledge innovatively is important. Data analysis, documentation, and reporting should be concise and rigorous. Excellent communication skills and proficiency in presenting to groups are required.

Qualifications

• Bachelor’s Degree or equivalent with typically 10 years of experience, Master’s Degree or equivalent with typically 8 years, or PhD with no experience necessary.

Additional Information

• The compensation range is based on job grade, geographic location, and other factors. The range may be modified in the future.
• We offer comprehensive benefits including paid time off, medical/dental/vision insurance, and 401(k).
• This role is eligible for short-term incentive programs.

Note: Compensation details are subject to change and are at the company's discretion.

AbbVie is an equal opportunity employer committed to integrity, innovation, and community service. We welcome veterans and individuals with disabilities.

For more information, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

Applicants seeking accommodations can learn more at https://www.abbvie.com/join-us/reasonable-accommodations.html.