Sr. Scientist, Discovery Oncology

Merck & Co.

Boston (MA)

On-site

USD 119,000 - 188,000

Full time

4 days ago
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Benefits offered by this job

Medical insurance
Dental insurance
Vision insurance
401(k)
Paid holidays
Vacation
Sick days

Job summary

Merck & Co. invites a highly qualified scientist in oncology to join the Discovery Oncology team in Boston.

The candidate will provide scientific leadership from the bench and drive the experimental strategy with deep cancer biology expertise, collaborating across multidisciplinary teams in early discovery. Key activities include leading mechanistic studies, biomarker discovery, and integration of literature to guide program direction.

Qualifications

  • Demonstrated ability to work independently to create and drive experimental strategy, interpret data, troubleshoot, and define critical next steps.
  • Strong experience in molecular and cellular biology techniques with emphasis on mammalian cell culture, western blot, ELISA/Mesoscale, flow cytometry, qPCR, stable cell line generation, CRISPR.
  • Strong team player and experienced working with collaborative cross functional teams.

Responsibilities

  • Scientific leadership through the development and implementation of multiple impactful experimental approaches to drive target validation, pathway interrogation, and mechanistic studies.
  • Contribute to therapeutic mechanistic understanding, biomarker discovery, and preclinical candidate characterization.
  • Monitor, review and interpret published literature to guide internal research.
  • Communicate experimental findings to stakeholders.
  • Leverage broad scientific expertise to influence scientific direction across programs.

Skills

Assay Development
Biology
Cancer Therapy
Cell Culture Techniques
Design of Experiments
Drug Target Identification
Flow Cytometry
Immunoassays
Independent Thinking
Mechanism of Action
Molecular Biology
Oncology
Target Discovery

Education

PhD or equivalent in oncology/biology/biochemistry/immunology
MS with 5+ years in pharma/biotech
BS with 7+ years in pharma/biotech

Job description

Job Description

We are seeking a highly qualified scientist with a strong background in oncology to join our Discovery Oncology team in Boston. The successful candidate will have a proven track record of-innovative, collaborative, and rigorous research. Primary responsibilities include providing scientific leadership from the bench, combining deep cancer biology expertise with creativity and rigor to drive the experimental strategy, and effectively communicating with multidisciplinary teams in the early discovery pipeline.

The specific responsibilities of the candidate include but are not limited to:
  • Scientific leadership through the development and implementation of multiple impactful experimental approaches, technologies, or capabilities to drive target validation, pathway interrogation, and mechanistic studies
  • Contribute to therapeutic mechanistic understanding, biomarker discovery, and preclinical candidate characterization
  • Monitor, review and critically interpret published literature to guide internal research
  • Effectively communicate experimental findings to appropriate stakeholders.
  • Leverage broad scientific expertise and deep domain knowledge to influence scientific direction
Education
  • PhD or equivalent in oncology, biology, biochemistry, immunology, or related STEM discipline and 0 years of experience; MS with 5+ yrs of experience; OR BS with 7+ yrs working experience in a pharma or biotech setting.
Required
  • Demonstrated ability to work independently to create and drive experimental strategy, interpret data, troubleshoot, and define critical next steps.
  • Strong experience in molecular and cellular biology techniques with an emphasis on mammalian cell culture, western blot, ELISA/Mesoscale, flow cytometry, qPCR, stable cell line generation, CRISPR.
  • Strong team player and experienced working with collaborative cross functional teams.
Preferred experience and skills
  • Previous experience working with different therapeutic modalities.
  • Experience integrating data from multiple experimental approaches to build mechanistic understanding, generate hypotheses, and connect experimental findings to broader program objectives to enable effective decision-making across stakeholders
  • Prior oncology research experience
Required Skills

Assay Development, Biology, Cancer Therapy, Cell Culture Techniques, Design of Experiments (DOE), Drug Target Identification, Flow Cytometry, Immunoassays, Independent Thinking, Mechanism of Action, Molecular Biology, Oncology, Target Discovery

US and Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer

We provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is $119,100.00 - $187,500.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .

San Francisco Residents Only

We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only

We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. -No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status

Regular

Relocation

Domestic

VISA Sponsorship

Yes

Travel Requirements

10%

Flexible Work Arrangements

Not Applicable

Shift

Not Indicated

Valid Driving License

No

Hazardous Material(s)

Standard lab reagents, BSL2, OEB4, OEB5, Bloodborne pathogens

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