Sr. Scientist, CMC Quantitative Sciences

Moderna Therapeutics; Norwood (MA); On-site; USD 131,000 - 209,000; Full time

Benefits offered by this job

Competitive healthcare

Well-being programs

Family planning benefits

Generous paid time off

Savings and investments

Job summary

Moderna Therapeutics in Norwood, MA is seeking a Senior Scientist to lead CMC QS statistical activities onsite. You will partner with Operations, Quality, Manufacturing Science and Technology, Analytical Development, and Technical Development to advance monitoring, predictive modeling, and data products.

You will mentor staff, promote statistical excellence, and contribute to regulatory submissions with clear interpretation of complex analyses for technical and non-technical audiences.

Qualifications

• PhD/MS/BS in Statistics or related STEM with strong quantitative background.
• Experience with DOE, regression, control charts, multivariate analysis.
• Experience in regulated analytic method lifecycle or product development.

Responsibilities

• Lead statistical support for analytical method and product lifecycle activities.
• Serve as SME on statistical aspects guiding experimental design and data analysis.
• Contribute to regulatory filings by authoring/reviewing statistical content.

Skills

Statistical thinking

Applied problem solving

Communication

Leadership

Mentoring

Education

PhD in Statistics

MS in Statistics or Biostatistics

BS in STEM

Tools

R

Python

SQL

JMP/Statistica/Minitab

Job description

The Role

Moderna is seeking a strategic, hands‑on Senior Scientist to join the CMC Quantitative Sciences (QS) team in Norwood, MA. As a key member of the team, you will serve as a statistical thought partner to Operations, Quality, Manufacturing Science and Technology, Analytical Development, and Technical Development organizations. You will be an integral part of advancing process monitoring and control tools, applying operational and predictive models, developing bespoke statistical analysis techniques, and innovating data products to solve critical business problems. You will also support regulatory submissions and help shape Moderna’s statistical approach to multiple business problems across the product, platform, and analytical method lifecycle. Beyond your technical contributions, you will mentor others and help build a culture of statistical excellence across CMC. This is an ideal role for someone who thrives in applied problem‑solving, enjoys coaching, and wants to make a tangible impact in a high‑paced, science‑first environment. The ideal candidate is self‑driven, an excellent communicator, and aligned with Moderna’s core values of being Bold, Collaborative, Curious, and Relentless. Your leadership will help ensure our statistical approaches remain innovative, scalable, and essential to the success of our growing therapeutic platform.

Here’s What You’ll Do

• Lead statistical support for analytical method and/or product lifecycle activities, including pre‑pivotal, clinical, and commercial programs


• Serve as a subject matter expert on statistical aspects of research and CMC activities, guiding experimental design, data analysis, and decision‑making


• Contribute to regulatory filings by authoring and reviewing statistical content for items such as comparability, analytical methods, stability, in regulatory submissions


• Drive analytical monitoring innovation by developing automated data monitoring systems and integrating industry best practices in product and analytical lifecycle activities


• Partner cross‑functionally with scientists, engineers, and quality teams to ensure experiments are well‑designed and statistical methods are appropriately applied


• Educate partners by building statistical literacy and promoting the use of sound statistical reasoning in decision‑making


• Communicate clearly to both technical and non‑technical audiences, translating complex analyses into actionable insights


• Champion statistical best practices to promote consistency, rigor, and scalability across CMC QS and the broader Moderna platform


• Stay current and contribute to the field through literature review, training, and conference engagement

Here’s What You’ll Bring to the Table

Minimum Qualifications

• PhD in Statistics (2+ yrs), MS (8 - 10 yrs), or BS (10 - 15 yrs) in Statistics, Biostatistics, Data Science, Applied Mathematics, Chemical Engineering, Biochemical Engineering, or a related STEM discipline.


• Strong foundation in applied statistical methods such as DOE, regression, capability analysis, control charts, and multivariate analysis.


• Experience with analytical method lifecycle and/or product development lifecycle activities in a regulated environment.


• Demonstrable experience with computer languages (R, Python, SQL, etc.) and statistical software packages (JMP, Statistica, Minitab, etc.) to manipulate and analyze data.


• Effective communicator who can translate statistical thinking into actionable strategies for non-statistical audiences.


• Understanding of regulatory guidance (e.g., ICH, FDA, EMA, WHO).

Preferred Qualifications

• Familiarity with eCTD submissions and response to HA questions.


• Experience with analytical QC automation, high-throughput methods, or large-scale monitoring systems.


• Knowledge of phase-appropriate GMP principles and risk-based decision making.

Competencies

• Skilled at balancing practical importance, business impact, and scientific rigor associated with decisions.


• Strong collaborative skills in a cross-functional matrix organizational structure.


• Capable of managing multiple projects in a dynamic environment.


• Detail-oriented with a passion for science and data analysis.


• Self-motivated with outstanding communication skills.


• Keen to learn & adapt, with the ability to pivot in the face of new data.

Working Model

This role is 100% onsite, reflecting the importance of being physically present to support the work, collaborate closely with colleagues, and contribute to our site-based operations. Working onsite enables real‑time collaboration, strong team connections, direct mentorship, and the hands‑on partnership needed to deliver our mission.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Pay & Benefits

• Competitive healthcare, plus voluntary benefit programs to support your unique needs


• A holistic approach to well‑being, with access to fitness, mindfulness, and mental health support


• Family planning benefits, including fertility, adoption, and surrogacy support


• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown


• Savings and investments to help you plan for the future

The salary range for this role is $130,800.00 - $209,400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world‑class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow.

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [e-mail].

Export Control Notice

Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

Our Mission and Vision

At Moderna we are pioneering the development of a new class of drugs made of messenger RNA (mRNA). This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells. We have a clear mission to propel the field of mRNA science forward and deliver new medicines to patients and a unique vision for how to achieve this mission. Our Mission: To deliver on the promise of transformative messenger RNA (mRNA) science to bring new medicines to patients. Our Vision: To unlock the potential of mRNA by establishing an ecosystem of teams and partners that will work together to develop the broadest possible array of drugs, across diverse therapeutic areas and routes of administration, for serious diseases that are not treatable today.

Third Party Staffing Agencies

Moderna does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Moderna from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Moderna and do not obligate Moderna to pay fees if we hire from those resumes.

Reasonable Accommodation Notice

Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Applicants with disabilities may be entitled to reasonable accommodation under the terms of the Americans with Disabilities Act and certain state or local laws. Please inform the company's personnel representative by calling 617-460-9346 or emailing [e-mail] if you need assistance completing any forms or to otherwise participate in the application process. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.