Sr Res Technologist (Meeks Lab)

Northwestern University; Chicago (IL); On-site; USD 77,145,600 - 99,187,200; Full time

Benefits offered by this job

Benefits package

Tuition benefits

Job summary

Northwestern University seeks a Scientist to oversee Meeks Lab operations, manage foundational bladder cancer research projects, and supervise daily lab activities. The role includes handling mouse colonies, complex molecular biology techniques, and collaboration with investigators at NU.

The ideal candidate will perform cell culture, sequencing, data analysis, and contribute to papers and grants, while guiding trainees and staff in experimental technologies for cancer research.

Qualifications

• Required: bachelor's degree in a scientific major or higher with relevant lab experience.
• Experience managing a research lab and coordinating complex experiments.
• Proven ability to supervise staff and oversee lab safety protocols.

Responsibilities

• Oversee operations of the laboratory including mouse colony management and molecular analyses.
• Participate in experiments and assist with single-cell RNA-seq and digital spatial profiling.
• Plan, perform and analyze experiments and collaborate with PI on publications and grants.
• Supervise and train lab staff, develop budgets and administrative procedures.
• Assist in IACUC and safety protocols; ensure compliance with standards.

Skills

Lab management

Molecular biology

Single-cell RNA-seq

Digital spatial profiling

Data analysis

Education

Bachelor's degree in a scientific major

Master's degree or higher

Tools

PCR

Flow cytometry

Immunohistochemistry

Job description

Job ID 54159

Location Chicago, Illinois

Department

MED-Urology

Salary/Grade

NEX/15

Target salary

Target hiring range for this position will be between be range is as be $27.06-$34.88 per hour. Offered salary will be determined by the applicant's education, experience, knowledge, skills and abilities, as well as internal equity and alignment with market data.

Job Summary

Conducts complex experimental research in a research lab, functioning as a specialist or technical expert. May manage one or more phase(s) of a major project(s) or all activities of a small project. May ensure overall lab compliance with all associated rules and regulations.

The Meeks Lab is seeking a Scientist who will oversee the operations of the laboratory, develop and manage foundational research projects in bladder cancer, especially the management of complex molecular biology techniques (single cell RNA-seq and digital spatial profiling), oversight of our mouse colony, and help in collaborations with investigators at NU. Our laboratory is vibrant, collaborative international group, fully supportive of each other to identify cures for bladder cancer. We are seeking to recruit a new laboratory manager that will make will manage daily operations of a research lab.

More specifically, the Scientist will:

• Help to supervise experiments and infrastructure of the lab, including mouse colony management, molecular biology techniques, cell culture, and genetic and protein analyses.
• Directly participate in experiments, and assist other laboratory members with cell culture experiments, single-cell RNA-seq and digital spatial profiling
• Independently plan, perform, and analyze experiments, and collaborate with PI on writing papers and grants;
• Serve as technical resource to, graduate and post-graduate trainees and provide insight, advice and guidance on experimental technologies for cancer research.
• Supervise and train lab support staff and oversee day-to-day operations of the laboratory, develops, implements & administers budgets, grant & administrative procedures.
• Assist in IACUC and laboratory research safety protocols, reviews technical operations ensuring that all processes, protocols & procedures are quality controlled & functioning up to standards

The ideal candidate will also have the following experience and qualifications:

• Provide administrative and operational leadership within the laboratory.
• Independently manage research projects and laboratory priorities.
• Develop and submit research protocols and amendments.
• Maintain and oversee mouse colonies and conduct mouse-related research.
• Perform bioinformatic analysis and interpret research data.
• Communicate scientific findings clearly with investigators, trainees, and collaborators.
• Demonstrate an interest in long-term growth and continuity within the laboratory.

Specific Responsibilities

• Acting as a technical expert or specialist in a particular field within a research lab, establishes and optimizes protocols and coordinates conduct of multiple complex experiments.

Molecular Biology

• DNA, RNA, Protein isolation, purification and expression
• Southern, Northern, Western blotting
• PCR, RT-PCR
• Plasmid preparation
• Cloning, mapping and sequencing of DNA
• Recombinant virus production and purification

Cellular Biology

• Cell culture, cell isolation
• Functional studies
• Transfection

Histology

• Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining
• Immunohistochemistry

Immunology

• Flow cytometry
• ELISA, Elispot assay
• Cytokine assay
• Antibody production and purification

Animal

• Husbandry
• Breeding and screening transgenic mice
• Dissections
• Blood collection
• Surgical procedures
• Database management of colony

Administration

• Oversees and manages lab databases which may include ensuring that experiments are observed and that data is collected and entered correctly.
• Reviews and analyzes data.
• Creates computer models, graphs, reports and summaries for use in publications, professional journals, and grant applications.
• Co-authors scientific papers for presentation and publication.
• Researches and obtains funding.
• Creates and maintains lab manuals regarding operating, safety, and etc. procedures.

Finance

• Creates lab financial plan and budget/audit expenses.
• Obtains sales quotes for lab equipment and supplies.
• Reviews and adjusts expenses to decrease costs.
• Oversees repair and maintenance of all lab equipment.
• Ensures that lab supplies are ready and available when necessary.

Supervision

• Trains, directs, assigns duties to and may supervise lab EEs, students, residents and/or fellows.

Miscellaneous

Performs other duties as assigned.

Minimum Qualifications

Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor\'s or higher degree in a scientific major or related; OR appropriate combination of education and experience and 5 years\' lab/bench or other relevant experience required; OR

Successful completion of a full course of study in an accredited college or university leading to a master\'s or higher degree in a scientific major or related; OR appropriate combination of education and experience and 3 years\' lab/bench or other relevant experience.

Benefits

At Northwestern, we are proud to provide meaningful and competitive benefits. The available benefits package for this position will include health, dental, vision, disability, and life insurance; paid vacation and holidays; paid medical/sick and parental leave; tuition benefits for the employee and dependents; pre-tax and flex spending accounts for commuting and dependent care; generous retirement savings options; and wellness programs. For a comprehensive overview of available benefits, including eligibility details, visit us at https://www.northwestern.edu/hr/benefits/index.html to learn more.

Work-Life and Wellness:

Northwestern offers comprehensive programs and services to help you and your family navigate life's challenges and opportunities, and adopt and maintain healthy lifestyles.

We support flexible work arrangements where possible and programs to help you locate and pay for quality, affordable childcare and senior/adult care. Visit us at https://www.northwestern.edu/hr/benefits/work-life/index.html to learn more.

Professional Growth & Development:

Northwestern supports employee career development in all circumstances whether your workspace is on campus or at home. If you're interested in developing your professional potential or continuing your formal education, we offer a variety of tools and resources. Visit us at https://www.northwestern.edu/hr/learning/index.html to learn more

Northwestern University is an Equal Opportunity Employer and does not discriminate on the basis of protected characteristics, including disability and veteran status. View Northwestern's non-discrimination statement. Job applicants who wish to request an accommodation in the application or hiring process should contact the Office of Civil Rights and Title IX Compliance. View additional information on the accommodations process.