Sr Manager, Enterprise Business Systems

Iambic Therapeutics, Inc; California; On-site; USD 150,000 - 210,000; Full time

Job summary

Iambic Therapeutics seeks an experienced Sr Manager, Enterprise Business Systems to lead and optimize critical G&A software across Finance, HR, Legal and Compliance, and Facilities. This role partners with function leaders to ensure secure, scalable systems and ongoing process improvements.

The position is based at our San Diego Headquarters and requires strong project management, vendor governance, and data integrity across enterprise applications.

Qualifications

• Bachelor’s degree in IT, CS, Business or related field.
• 12 years IT experience with 8+ years in cross‑functional business apps across G&A.
• Experience with SOX, HR and Legal systems access, confidentiality, retention requirements.
• Knowledge of GDPR, CCPA, HIPAA, and Transparency Reporting.
• Experience implementing and improving Finance, HR, Legal and Compliance systems like NetSuite, Adaptive, Procurify, HRIS, Ashby ATS, DocuSign, Ironclad.
• Experience managing SaaS vendors, contracts, renewals, and licenses.
• Experience in system implementation, data migration, or process automation.
• Strong communication and collaboration skills; IT service management and IAM knowledge preferred.
• Project management experience or certifications preferred.

Responsibilities

• Oversee implementation, configuration, maintenance, and support of G&A enterprise apps.
• Collaborate with G&A leaders to optimize workflows and drive process improvement.
• Ensure security, RBAC, segregation of duties, and policy compliance across systems.
• Perform regular updates, patches, and upgrades to maintain performance and security.
• Liaise with vendors for support and upgrades and manage data migrations.

Skills

Communication

Analytical skills

Problem solving

Project management

Vendor management

IT service mgmt

Data privacy

Regulatory compliance

Education

Bachelor’s degree in IT/CS/Business

Tools

NetSuite

Adaptive

Procurify

HRIS

Ashby ATS

DocuSign

Ironclad

Job description

JOB SUMMARY

We are seeking an experienced and results-driven Sr Manager, Enterprise Business Systems to join our growing IT team. This role will oversee the implementation, configuration, maintenance, and support of business-critical applications across the organization, with primary focus on the systems that run our General & Administrative (G&A) functions: Finance and Accounting, People/HR, Legal and Compliance, and Facilities, IT Operations, and Business Operations.

The Sr. Manager, Enterprise Business Systems will collaborate with leaders across each G&A function to optimize workflows, troubleshoot system issues, and drive continuous improvement in business processes. This role ensures that business applications operate efficiently, securely, and meet the evolving strategic and tactical needs of the company.

This position will be based out of our San Diego Headquarters.

KEY RESPONSIBILITIES

• Apply deep working knowledge of enterprise software across the G&A landscape to implement, integrate, and maintain business applications supporting:
• Finance and Accounting (ERP, budget forecasting & tracking, procurement, invoicing & expenses),
• People/HR (HRIS, payroll, talent acquisition, learning management)
• Legal and Compliance (contract lifecycle management, e-signature, entity management)
• Facilities/Operations (service management, asset and space management).
• Ensure application security, role-based access controls, segregation of duties, and compliance with company policies across all G&A systems.
• Perform regular system updates, patches, and upgrades to maintain performance and security.
• Liaise with software vendors and service providers for application support and upgrades.
• Integrate business applications with other systems and third-party tools and assist in data migrations, imports, and exports between systems.

QUALIFICATIONS

• Bachelor’s degree in Information Technology, Computer Science, Business Administration, or a related field.
• 12 years IT experience, with 8+ years administering cross-functional business applications spanning multiple G&A functions, life sciences experience preferred
• Experience supporting financial processing and audit controls for Sarbanes-Oxley compliance, as well as the access, confidentiality, and retention requirements of HR and Legal systems.
• Working knowledge of data privacy and associated regulatory requirements such as GDPR, CCPA, HIPAA, and Transparency Reporting.
• Strong experience implementing, maintaining and improving Finance, Procurement, HR, Legal and Compliance systems such as NetSuite, Adaptive, Procurify, HRIS, Ashby ATS, DocuSign, and Ironclad preferred
• Experience managing SaaS vendor relationships, contracts, renewals, and license optimization across a portfolio of business applications.
• Experience in system implementation, data migration, or process automation.
• Excellent communication and collaboration abilities with strong analytical and problem-solving skills.
• Prior experience with IT service management, identity and access management (SSO, SCIM, provisioning), and corporate IT or facilities systems preferred
• Experience with reporting methodologies and business metrics preferred
• Project management experience or certifications (e.g., PMP, ITIL, Agile) preferred

ABOUT IAMBIC THERAPEUTICS

Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. By utilizing molecular superintelligence — integrating proprietary AI with automated, scalable chemistry and biology experimentation — our platform is designed to address the totality of drug discovery and development. At Iambic, we are building an engine that is designed to power the future of medicine. Learn more at iambic.ai.

MISSION & VALUES

Our mission is to make better technology for better medicines. Three values guide how we work:

• Bold. We are courageous, take thoughtful risks, and approach challenges with tenacity.
• Innovative. We are creative and find new solutions that deliver impact.
• Collaborative. We respect one another and partner with integrity.

We value the range of perspectives our people bring, and we work to build an environment where every team member can contribute and grow.

PAY AND BENEFITS

The pay range for this role is listed above. Actual pay depends on factors including experience, skills, and location. Eligible employees in the U.S. receive company-paid medical coverage, flexible spending accounts, voluntary life insurance, 401(k) matching and flexible time off. We are in a brand-new state-of-the art facility in beautiful San Diego with a community gym, dining, and easy access to great places to live and play.

EQUAL OPPORTUNITY

Iambic is an equal opportunity employer. We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, ancestry, age, disability, medical condition, genetic information, marital status, veteran or military status, or any other characteristic protected by law.