Sr Manager Business Performance & Digital Enablement - Remote

Amgen SA; Northern (KY); Hybrid; USD 140,000 - 200,000; Full time

Benefits offered by this job

Competitive benefits

Flexible work model

Career development

Stock-based incentives

Job summary

Amgen is seeking a Sr Manager, Business Performance & Digital Enablement in the United States to translate strategic priorities into scalable, technology-enabled capabilities and disciplined governance. You will lead a matrixed team and partner with DTI, MD&A, AI&D, Medical, and R&D to deliver measurable business outcomes.

The role requires advanced degrees with substantial leadership experience and a track record in digital enablement and data-driven decision making.

Qualifications

• Basic qualifications include Doctorate or Master’s with years of experience in business performance and digital enablement, plus leadership experience.
• Strong collaboration across Medical, Technology, Data & Analytics, R&D, Global Markets & Policy, Commercialization, Finance, Procurement, and external partners.

Responsibilities

• Translate strategy into scalable operating models and governance.
• Own AUGment platform and drive technology-enabled capabilities.
• Lead cross-functional delivery and prioritization.
• Define data strategy, KPIs, and executive dashboards.
• Ensure adoption of AI-ready data foundations and analytics.

Education

Doctorate degree

Master’s degree

Bachelor’s degree

Associate’s degree

High school diploma / GED

People leadership experience

Job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr Manager Business Performance & Digital Enablement

Live

What you will do

Let’s do this. Let’s change the world. The AUEG (Access & Use Evidence Generation) Business Performance Sr. Mgr. is responsible for translating Global AUEG Portfolio Strategy, Governance, and Process framework into execution ready and scalable digital operating models with advancements in technology including AI. This role serves as the integrator and liaison between AUEG Capability and internal Digital Technology & Innovation (DTI), Artificial Intelligence & Data (AI& D) teams and external partners. The Sr. Manager leads the build and delivery of the cross functional, matrixed AUEG technology platform (AUGment) aimed at enabling disciplined prioritization, governance, execution, and management of global, regional and local AUEG activities in collaboration with DTI, AI&D and functional partners in Medical, R&D, and Global Markets & Policy.

This role leads delivery of the enhancement road map of the evolution of AUEG capability that will enable timely prioritization and execution of AUEG activities and demonstrates the realized AUEG impact. As the business owner for the AUGment platform and a strategic business partner to DTI, Medical Data & Analytics (MD&A), and AI& D, the Senior Manager translates business priorities into scalable capabilities enabled through business processes and technology to impact realization.

Working across a highly matrixed environment, this role partners cross-functionally to strengthen organizational performance to accelerate adoption of technology-enabled capabilities and deliver measurable business outcomes. Success in this role requires strong business acumen, information technology understanding and ability to influence across organizational boundaries to deliver meaningful results.

Key Responsibilities

Business Strategy & Capability Development

• Translate AUEG Capability strategy and long-term roadmap into scalable, operating models, business processes for enterprise execution, with clean CORE and FAIR data technology-enabled solutions.
• Manage and execute on governance, performance measures, and operating standards that support consistent execution and informed decision‑making via technology solutions.
• Partner with AUEG leadership to continuously evolve AUEG capabilities and improve performance.
• Drive continuous improvement through people, processes, technology, and data.

AUGment Business Ownership & Digital Enablement

• Partner with DTI, AI&D Product Managers and Solution Architects to translate strategic priorities into technology-enabled business capabilities.
• Serve as the business owner for AUGment and other integrated business enablement technologies.
• Oversee delivery of the AUGment enhancement roadmap aligned with AUEG priorities.
• Lead business requirements, process design, user acceptance testing, deployment, and organizational adoption.
• Identify and lead opportunities to leverage AI, automation, and emerging technologies to continuously evolve business capabilities and improve business performance.
• Oversee business-owned collaboration and knowledge management solutions that support the AUEG capability.

Data Strategy & Business Insights

• Define the AUEG data strategy, roadmap and business reporting framework.
• Strengthen data quality, governance, and stewardship of business information.
• Establish and continuously evolve meaningful business impact metrics, KPIs, and executive dashboards.
• Deliver actionable portfolio insights that support strategic and operational decisions.
• Advance AI-ready data foundations and analytical capabilities that enable evolving capabilities.

Strategic Partnerships, Adoption & People Leadership

• Serve as the primary business partner to DTI and MD&A.
• Build trusted partnerships across Medical, Technology, Data & Analytics, R&D, Global Markets & Policy, Commercialization, Finance, Procurement, and external vendor partners.
• Translate evolving needs into prioritized capabilities, roadmap enhancements, and technology investments.
• Lead stakeholder engagement, communication, training, and adoption of technology-enabled business capabilities.
• Identify business risks, develop & implement mitigation strategies.
• Lead a high‑performing matrixed team responsible for operational support, reporting, platform administration, and business services for the AUEG organization.
• Coach and develop team members while establishing scalable operating practices, performance expectations, and continuous improvement initiatives that enable reliable, high‑quality business services.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The strategic professional we seek is a motivated professional with these qualifications.

Basic Qualifications:

• Doctorate degree and 2 years of business performance and digital enablement experience OR
• Master’s degree and 6 years of business performance and digital enablement experience OR
• Bachelor’s degree and 8 years ofbusiness performance and digital enablement experience OR
• Associate’s degree and 10 years of business performance and digital enablement experience OR
• High school diploma / GED and 12 years ofbusiness performance and digital enablement experience
• In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications

• Advanced degree in Business, Life Sciences, Computer Science, Engineering, or a related discipline.
• 8+ years of experience leading business operations, business capability enablement, digital enablement, business performance, technology implementation, or business transformation within the pharmaceutical, biotechnology, or healthcare industry.
• Experience serving as a business owner or platform owner for enterprise technology platforms that enable scalable business capabilities.
• Demonstrated success evolving technology-enabled capabilities through process optimization, technology enablement, and operational excellence.
• Experience integrating business, technology, data, and AI capabilities to deliver measurable business outcomes.
• Strong understanding of Medical Affairs, Evidence Generation, drug development, commercialization, and the healthcare ecosystem.
• Experience leading cross-functional initiatives in highly matrixed organizations.
• Experience managing business operations, budgets, vendors, or external partners.
• Knowledge of GxP, SOPs, regulatory requirements, and validated business processes.
• Experience driving organizational adoption and continuous improvement of technology-enabled business capabilities.

Thrive

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan
• Stock‑based long‑term incentives
• Award‑winning time‑off plans and bi‑annual company‑wide shutdowns
• Flexible work models, including remote and hybrid work arrangements, where possible

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.