Sr. Manager/Associate Director Chemistry

Corvus Pharmaceuticals; South San Francisco (CA); On-site; USD 160,000 - 195,000; Full time

Job summary

A biotechnology company in South San Francisco seeks a qualified professional to design synthetic strategies and develop drug candidates. Candidates must have a PhD in Chemistry and at least 5 years of experience. The role involves collaboration within multidisciplinary teams and requires excellent communication skills. A salary range of $160,000 to $195,000 is offered for this full-time position.

Qualifications

• PhD in Chemistry plus 5+ years of related experience in pharmaceutical or biotechnology industry or equivalent.
• Demonstrated expertise in synthetic organic chemistry.
• Solid understanding of modern analytical techniques (NMR, HPLC, MS).
• Excellent verbal and written communication skills.

Responsibilities

• Independently design synthetic strategies and synthesize precursor compounds.
• Design small-molecule drug candidates based on biological activity and physicochemical data.
• Purify and characterize molecules with standard analytical techniques.
• Write and review manuscripts for publication.

Job description

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Base pay range

$160,000.00/yr - $195,000.00/yr

Role and Responsibilities

• Independently design synthetic strategies and use those strategies to synthesize and characterize precursor compounds, starting materials, intermediates, reference compounds, and new chemical entities
• Design small-molecule drug candidates based on in vitro and in vivo biological activity, ADME/PK, physicochemical and IP-relevant data.
• Purify and characterize molecules with standard analytical techniques (e.g. HPLC, LCMS, NMR)
• Use computation and structural data and information to design molecules
• Perform research and/or development in collaboration with others in chemistry and biology; make detailed observations and analyzes data.
• Prepare batch records, technical reports, summaries, protocols and quantitative analyses
• Write and review manuscripts for publication
• Provide support in corporate research and development of patent applications
• Develop strategies to ensure effective achievement of scientific objectives
• Uses skills to contribute to development of company objectives and principles and to achieve goals in creative and effective ways
• Exercises independent judgment in selecting methods, techniques and evaluation criteria for obtaining results

Qualifications and Education Requirements

• PhD in Chemistry plus 5+ years of related experience in pharmaceutical or biotechnology industry or equivalent.
• Demonstrated expertise in synthetic organic chemistry
• Must possess expert knowledge of scientific principles and concepts.
• A solid understanding of modern analytical techniques (NMR, HPLC, MS)
• Excellent verbal and written communication skills and the ability to collaborate effectively within a multidisciplinary team

Preferred Skills

• Experience in designing and synthesizing PROTACs or molecular glues is strongly preferred
• Molecular modeling and computational methods
• Able to manage outside vendor collaborations
• Flexibility and willingness to solve problems that fall outside of immediate area of expertise
• Work independently in an interdisciplinary, fast-paced, often changing environment.
• Committed to the values of integrity, accountability, transparency, and drive.

Local candidates only.

Salary Range: $160,000 to $195,000

Employment type

• Full-time

Job function

• Science

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