Sr. Infrastructure Engineer

Quanterix; Billerica (MA); On-site; USD 140,000 - 200,000; Full time

Benefits offered by this job

401k with employer match

Health benefits

Unlimited vacation

Equity participation

Tuition assistance

Onsite fitness center

Free snacks

Job summary

Quanterix is seeking a Sr. Infrastructure Engineer in Billerica, MA to lead enterprise cloud and infrastructure services. You’ll translate requirements into scalable, automated solutions with emphasis on high availability, capacity, monitoring, and security.

The role spans multiple projects and requires self‑direction and collaboration with IT teams. You will work on establishing enterprise capabilities, hosting solutions, SLAs, and operational procedures, while mentoring teammates and driving

Qualifications

• Bachelor's degree in information systems or equivalent experience.
• 10+ years of IT experience in an enterprise operational environment with Windows server maintenance, troubleshooting, optimization, deployment, and migration.
• 5+ years of experience with Active Directory, VMware, Entra ID, Microsoft 365, and Azure resources.

Responsibilities

• Apply practical knowledge across a broad range of infrastructure technologies and best practices.
• Own all phases of solution delivery lifecycle from requirements to support.
• Ensure high availability, performance, and security of mission‑critical resources.
• Develop and maintain automation/scripts for operational reliability.
• Mentor team members and drive security and patch management programs.

Skills

Windows Server

Active Directory

VMware

Azure

Entra ID

Microsoft 365

Scripting

Security

Education

Bachelor's degree in information systems or equivalent

Tools

PowerShell

Azure

VMware ESXi

Job description

Sr. Infrastructure Engineer

Billerica, MA

Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its vision is to lead the next era of precision biomarker science to power earlier detection, better decisions, and improved human health. Its mission is to make biology measurable at its most fundamental level, delivering earlier insight when it matters most. Across discovery to clinical applications, Quanterix empowers scientists and healthcare providers to improve patients' lives through detection and understanding of disease. Its proprietary Simoa technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue-advancing precision medicine from discovery to diagnostics.

ROLE SUMMARY

You will be a member of our IT team focused on building and maintaining enterprise-level cloud and infrastructure services. In this role, you will apply a broad range of service delivery engineering concepts, practices, and procedures to resolve complex issues in creative and practical ways. As a self-starter, you will make quick, effective decisions, translate management requirements into scalable solutions, and implement services focused on high availability, automation, capacity, monitoring, and security. You will work on multiple projects of moderate complexity, exercise sound judgment in selecting methods and techniques, and use your expertise to develop solutions that support business needs.

WHAT YOU'LL DO

• Apply practical knowledge and hands‑on experience across a broad range of infrastructure technologies, best practices, processes, and procedures.
• Work across all phases of the solution delivery lifecycle, including requirements definition, architecture, design, implementation, and support.
• Establish, operate, and leverage enterprise capabilities, hosting solutions, infrastructure services, SLAs, and OLAs.
• Build and maintain collaborative working relationships across the IT organization.
• Design and evaluate solutions at both tactical and strategic levels.
• Resolve complex issues and develop innovative solutions in collaboration with other IT disciplines.
• Develop system and application implementation plans, custom scripts, and testing procedures to ensure operational reliability.
• Ensure high availability and acceptable performance levels for mission‑critical resources.
• Develop procedures, programs, and documentation for backup and restoration of operating systems and applications.
• Develop and implement system disaster recovery and business continuity plans.
• Evaluate, recommend, and execute new technologies and update existing infrastructure to optimize systems and network performance.
• Troubleshoot hardware and software issues and partner with IT staff or vendors to perform complex testing, support, and troubleshooting.
• Forecast system demand and recommend upgrades, expansion, and reconfiguration.
• Partner with other IT teams on infrastructure projects and provide Tier 3 support for complex enterprise infrastructure issues.
• Communicate complex ideas, issues, and designs to varied audiences.
• Develop, perform, and enforce best practices for systems management, including configuration, monitoring, alerting, patch management, and security.
• Proactively manage and maintain core Windows and VMware systems, establish operating system build standards, and perform quarterly patching.
• Mentor and cross‑train team members on existing and new technologies.
• Conduct reviews and technical inspections to identify and mitigate potential security weaknesses and ensure applied security features are implemented and functional.
• Create and implement procedures to monitor IT systems for suspicious activity that could indicate attempted or actual security incidents or data leakage events.
• Perform other duties as assigned.

BASIC QUALIFICATIONS

• Bachelor’s degree in information systems or equivalent relevant experience.
• 10+ years of IT experience in an enterprise operational environment working with Windows server maintenance, troubleshooting, optimization, deployment, and migration.
• 5+ years of experience with Active Directory, VMware, Entra ID, Microsoft 365, and Azure resources.

PREFERRED QUALIFICATIONS

• Microsoft and network administration coursework and/or certifications.
• Knowledge of TCP/IP networks.
• Experience managing Microsoft server environments.
• Technical understanding of network protocols and services including IP, FTP, DNS, DHCP, SMTP, NFS, SNMP, BGP, SSH, SFTP, and VPN.
• Experience with network hardening, including firewall devices, ACL management, and network segmentation in a medium to large infrastructure environment.
• Proven experience with virtualization stacks such as ESXi and Hyper‑V.
• Hands‑on technical experience with storage technologies as they apply to virtualization and relevant backup solutions.
• Experience with common IT tools for monitoring, alerting, analytics, and change management.

EXPECTATIONS, COMPETENCIES, SKILLS & ABILITIES

• This position is located in Billerica, MA.
• Occasional travel of less than 5% to remote locations may be required.
• Night or weekend work may be required as needed.
• Employee may be required to lift and/or move objects up to 50 pounds.
• Hands‑on experience with authentication, authorization, and accounting technologies, including LDAP, NPS, PAM, Active Directory, Entra ID, and SSO technologies such as SAML.
• Administration experience with cloud environments related to core infrastructure, including Microsoft 365, Azure resources, and AWS.
• Experience with telephony and Microsoft Teams.
• Experience with scripting and task automation.
• Experience with operating system hardening, patching, remediation, performance tuning, capacity management, and server monitoring.
• Excellent leadership, analytical, problem‑solving, consensus‑building, and results‑oriented skills with the ability to act quickly to achieve goals.
• Solid technical grounding, project management, implementation experience, and proven system architecture and design abilities.

WHY YOU'LL LIKE WORKING WITH US

OUR TECHNOLOGY

From discovery to diagnostics, Quanterix's ultrasensitive biomarker detection is fueling breakthroughs only made possible through its unparalleled sensitivity and flexibility. Simoa technology has delivered the gold standard for earlier biomarker detection in blood, serum or plasma, with the ability to quantify proteins that are far lower than the Level of Quantification (LoQ). Our industry‑leading precision instruments, digital immunoassay technology and CLIA‑certified Accelerator laboratory have supported research that advances disease understanding and management in neurology, oncology, immunology, cardiology, and infectious disease.

Akoya Biosciences, a Quanterix company, is The Spatial Biology Company-bringing tissue context to life through high‑resolution, single‑cell imaging. Akoya's spatial phenotyping platforms help researchers visualize and measure how cells organize and interact within tissue to influence disease progression and therapeutic response. From discovery through clinical research, Akoya offers a full continuum of solutions, including PhenoCycler, PhenoImager Fusion and HT, and PhenoCode Panels. As part of Quanterix, Akoya complements a leading portfolio of ultra‑sensitive biomarker detection technologies, together enabling a more complete view of biology and disease across both tissue and blood.

OUR COMMITMENT TO EMPLOYEES

At Quanterix, our values are based on: Team, Innovation, Customer and Owner.

Team: Challenge assumptions, not the person. Respect diversity of thought and hold ourselves to lofty standards.

Innovation: Stay curious, experiment, create and change.

Customer: Prioritize and celebrate these pioneers by doing our best to deliver on commitments.

Owner: Act with high integrity and in the best interest of Quanterix. Take measured risks and learn from their success and failures.

• competitive compensation and a 401k plan with employer match
• competitive health, dental, and vision benefits for employees and their dependents
• unlimited vacation policy to all exempt employees, and a generous PTO policy for non‑exempt employees
• All employees are eligible for equity, employee stock purchase plan, a performance bonus, and 1:1 financial counseling/planning
• We also offer Tuition Assistance
• We have a free, state‑of‑the‑art onsite fitness center for all employees
• To keep you fueled up, we provide onsite employees free snacks and drinks every day

DIVERSE & INCLUSIVE WORKPLACE

Quanterix is committed to a Diverse and Inclusive workplace. We strive to recruit candidates who will bring inclusive mindsets and contribute to our values.

Quanterix is an Equal Opportunity Employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Quanterix will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.