Sr Bioinformatics Research Scientist

Veracyte; United States; Remote; USD 140,000 - 169,000; Full time

Job summary

Join a pioneering team dedicated to transforming cancer care as a Sr Bioinformatics Research Scientist. This role offers the chance to analyze genomic data and apply machine learning to enhance our understanding of cancer. Collaborate with experienced professionals and contribute to impactful projects that improve patient outcomes. With a focus on innovation and collaboration, this position is perfect for those eager to learn and make a difference in the field of cancer genomics. Enjoy a supportive work environment that values your contributions and fosters your growth.

Benefits

Competitive Compensation

Inclusive Workforce

Career Growth Opportunities

Flexible Work Environment

Qualifications

• 4-5 years of post-graduate experience in cancer genomics.
• In-depth understanding of DNA-/RNA-seq analysis.

Responsibilities

• Analyze gene expression data to build genomic signatures.
• Develop NGS pipelines for genomic alterations.
• Conduct statistical analysis and survival modelling.

Skills

R Programming

NGS Pipelines

Statistical Analysis

Machine Learning

Data Visualization

Education

PhD in Cancer Biology

PhD in Bioinformatics

PhD in Statistics

Tools

AWS

U-MAP

Job description

At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte – whether it be in one of our labs, corporate offices, the field – enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a results-driven environment that values innovation, collaboration, and compassion.

The Position:

We are seeking a talented and motivated Sr Bioinformatics Research Scientist to join the Clinical Evidence team within Veracyte’s Data Analysis Team (DAT). The individual will be responsible for analyzing transcriptomic and genomic data, and applying machine learning models to Veracyte’s large database of cancer genomics data to identify clinically relevant signatures that improve our molecular understanding of disease pathology and progression. A core objective of this work is to build supervised and unsupervised models to predict different biological and clinical endpoints as well as define molecularly distinct subtypes. The candidate will contribute to a diverse profile of projects analyzing gene expression and NGS data. This position offers a unique opportunity to work with experienced professionals including academic and clinical researchers, practicing oncologists, and commercial partners with whom the candidate will discuss and present their work. These projects represent a critical part of Veracyte’s successful suite of research products, requiring a candidate that can implement and translate new computational methods to our data sets, eager to learn the biology and clinical aspects of new diseases (i.e. thyroid cancer, prostate cancer, breast cancer), and who possesses strong analytical, problem-solving, and story-telling skills.

KEY RESPONSIBILITIES:

• Analyze both internal and external (including public) gene expression data with matched biological endpoints to build genomic signatures able to predict said endpoints.
• Assess and optimize existing gene expression models and improve their specificity and sensitivity.
• Develop and run NGS pipelines to call genomic alterations and analyze them in the context of clinical questions.
• Review and synthesize literature on cancer gene signatures and genomic alterations predictive of disease progression and treatment outcome.
• Explore and implement cutting edge machine learning models to further enhance our product offerings.
• Conduct statistical analysis and survival modelling for clinical events.
• Produce professional visualizations, summarize analyses, and present results to both internal and external stakeholders.
• Independently drive projects from conceptualization to publication

Who You Are:

• PhD. in Cancer Biology, Bioinformatics, Statistics or related field with 4-5 years of relevant post-graduate experience (postdoc or industry; background in cancer genomics a plus).
• In-depth understanding of NGS pipelines and DNA-/RNA-seq analysis.
• Expertise in R programming and data analysis.
• Strong proficiency in feature reduction techniques and visualization (e.g., U-MAP), supervised and unsupervised learning algorithms, and model performance evaluation.
  • Hands-on experience with cloud-based compute architectures (AWS preferred).
• Excellent ability to summarize and communicate complex data findings with clarity.
• Ability to work effectively in a fast-paced and collaborative environment.

LOCATION:

• This is a remote friendly position in US or Canada.
• On-site office available in South San Francisco or San Diego.

#LI-Remote

The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units. Veracyte is a multi-state employer, and this salary range may not reflect positions that work in other states.

Pay range

$140,000—$169,000 USD

What We Can Offer You

Veracyte is a growing company that offers significant career opportunities if you are curious, driven, patient-oriented and aspire to help us build a great company. We offer competitive compensation and benefits, and are committed to fostering an inclusive workforce, where diverse backgrounds are represented, engaged, and empowered to drive innovative ideas and decisions. We are thrilled to be recognized as a 2024 Certified Great Place to Work in both the US and Israel - a testament to our dynamic, inclusive, and inspiring workplace where passion meets purpose.

About Veracyte

Veracyte(Nasdaq: VCYT) is a global genomic diagnostics company that improves patient care by providing answers to clinical questions, informing diagnosis and treatment decisions throughout the patient journey in cancer and other diseases. The company’s growing menu of genomic tests leverage advances in genomic science and technology, enabling patients to avoid risky, costly diagnostic procedures and quicken time to appropriate treatment. The company’s tests in lung cancer, prostate cancer, breast cancer, thyroid cancer, bladder cancer and idiopathic pulmonary fibrosis are available to patients and its lymphoma subtyping and renal cancer tests are in development. With Veracyte’s exclusive global license to a best-in-class diagnostics instrument platform, the company is positioned to deliver its tests to patients worldwide.Veracyteis based inSouth San Francisco, California. For more information, please visitwww.veracyte.com and follow the company on X (Formerly Twitter).

Veracyte, Inc. is an Equal Opportunity Employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability status. Veracyte participates in E-Verify in the United States. View ourCCPA Disclosure Notice.

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