Sr Assoc Scientist, Drug Product Process Development

Regeneron Pharmaceuticals, Inc.; United States; On-site; USD 80,000 - 131,000; Full time

Benefits offered by this job

Student Loan Paydown

Tuition Reimbursement

Family Care Benefits

Relocation Assistance

Well-Being Programs

Job summary

Regeneron Pharmaceuticals, Inc. is seeking a Sr. Associate Scientist to join the DPDT Process Development Team in Tarrytown, NY.

You will design and execute drug product process development studies for biologics, including mAbs and non-traditional modalities, supporting tech transfer and GMP activities. You will work with DPDT leads to optimize unit operations, develop small-scale models, and contribute to toxicological campaigns, while preparing technical reports and presenting findings at

Qualifications

• BS with 6+ years or MS with 3–6+ years in biotech/pharma.
• Experience in drug product development and characterization.
• Hands-on analytical skills for biologics (HPLC, icIEF, SEC, IEX; DLS, DSC, UV-Vis).
• Knowledge of protein degradation pathways.
• Strong problem-solving and communication skills.

Responsibilities

• Plan and execute drug product process development studies for unit operations (freeze/thaw, lyophilization, mixing, filtration, filling).
• Develop small-scale models to mimic manufacturing operations and support tech transfer.
• Support in-house drug product toxicological campaigns as needed.
• Collaborate with DPDT leads/scientists for progression of late-stage activities.
• Prepare, review, and edit technical reports.
• Present work at group, department, and cross-functional meetings.
• Manage equipment installation, operation, maintenance, calibration, and repairs.

Skills

HPLC

icIEF

SEC

IEX

DLS

DSC

UV-Vis

MFI

HIAC

Protein degradation

Education

Bachelor's degree in Biomedical/Chemical Engineering or related

MS degree in related field

Job description

Regeneron Overview

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Sr. Associate Scientist to join our Drug Product Development and Technology Group (DPDT) Process Development Team. In this role, you will support drug product process development studies for biologics, including traditional monoclonal antibody (mAb) and non-traditional modalities (e.g., AAV, antibody tethered ligand, etc.), working closely with DPDT leads and scientists to ensure seamless technology transfer to various manufacturing sites and provide technical support toward GMP manufacturing, validation campaigns, and post-launch activities. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Shift Requirements & Location

Full-time. On-site in Tarrytown, NY. Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site.

Responsibilities

• Plan, optimize, design, and execute drug product process development studies to ensure robust characterization of different unit operations (freeze/thaw, lyophilization, mixing, filtration, filling, etc.)
• Assist in developing small-scale models to effectively mimic manufacturing unit operations and support technology transfer to manufacturing teams
• Support in-house drug product toxicological lot manufacturing campaigns as needed
• Work closely with DPDT leads/scientists to ensure seamless progression of multiple late-stage process-related activities
• Prepare, review, and edit technical reports
• Bring in new ideas from literature and present work at group, department, and cross-functional meetings
• Manage process development equipment installation, operation, maintenance, calibration, and repairs

Requirements

• BS degree in Biomedical or Chemical Engineering, Pharmaceutical Sciences, or a related field with 6+ years of relevant industry experience, or an MS degree with 3-6+ years of relevant industry experience
• Experience with drug product development and characterization (formulation and process)
• Hands-on experience with analytical instruments used for biologics, including HPLC-based chromatographic techniques (icIEF, SEC, IEX), biophysical methods (DLS, DSC, and UV-Vis), and particle characterization methods (MFI and HIAC)
• Basic understanding of common protein degradation pathways and biophysics
• Demonstrated strong and proactive problem-solving skills via critical thinking and effective communication

Preferred / Nice-to-haves

• Experience with lyophilization
• Other quantification methods (ddPCR, ELLA, mass photometry)
• Experience with statistical software (JMP) to perform design of experiments and statistical analyses

Benefits

• Student Loan Paydown program
• Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well-Being programs (including physical & mental health)

EEO / DEI Statement

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Salary Range

Salary Range (annually) $80,300.00 - $131,100.00

Company Description

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician‑scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA‑approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.