Spring Co-op: Data Science for mRNA Process & CMC

Sanofi Group

Waltham (MA)

On-site

USD 48,000 - 83,000

Full time

9 days ago

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Job summary

Sanofi in Waltham, MA is seeking a Spring Co-op to join the Process and CMC Data Science team for six months. You will build first-principle, ML, and hybrid models for mRNA process ops like IVT, TFF, chromatography, under mentorship.

You will gain hands-on experience with mRNA technology and data-driven process development, learn to design DoE, quantify uncertainties, and present results to cross-functional teams.

Qualifications

  • Pursuing a Master's or PhD in a quantitative field.
  • Must be permanently authorized to work in the U.S. and not require visa sponsorship.
  • Must be enrolled in an accredited college/university for the duration of the co-op.
  • Must relocate to the office and work 40 hrs/week, Monday to Friday.

Responsibilities

  • Develop and validate first-principle, ML, and hybrid models for IVT, TFF, and Chromatography.
  • Investigate impact of process parameters on CQAs and quantify uncertainties.
  • Design and execute DoE for model structure, parameter estimation, and optimization.
  • Analyze experimental and simulation data to inform process development decisions.
  • Document modeling workflows, results and recommendations in technical reports.

Skills

Python
DoE
First-principles modeling
ML/Hybrid modeling

Education

Master's or PhD in Chemical Engineering
Biochemical Engineering
Biochemistry
Data Science
Computer Science
Biomedical Engineering
Applied Mathematics
Analytical Chemistry
Physics
Software Engineering

Tools

MATLAB
Julia
gPROMS
BOTorch
PYOMO

Job description

Sanofi in Waltham, MA is seeking a Spring Co-op to join the Process and CMC Data Science team for six months. You will build first-principle, ML, and hybrid models for mRNA process ops like IVT, TFF, chromatography, under mentorship.

You will gain hands-on experience with mRNA technology and data-driven process development, learn to design DoE, quantify uncertainties, and present results to cross-functional teams.

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