Software Engineer, Agentic AI

Dotmatics Ltd.

United States

Remote

USD 124,000 - 168,000

Full time

7 days ago
Be an early applicant

Get a reply from this employer

Your resume and cover letter, tailored to exactly what they’re hiring for.

Get past ATS filters

Benefits offered by this job

Medical, Dental, Vision Insurance
Health Spending Accounts
Wellness Benefits
Life and Disability Insurance
401k with company match
Flexible Time Off

Job summary

Dotmatics, a Siemens company, seeks an experienced Software Engineer (Agentic AI) to own the AI agent end-to-end within the Luma platform. You will define how it reasons, which tools it uses, what it remembers, and how it recovers from failures, in a small, high-trust team with scientists and product partners.

You’ll focus on AI-native engineering, producing production-grade agents, validating outputs with tests, and shipping robust software faster than traditional approaches while maintaining

Qualifications

  • Experience building LLM-powered agents in production.
  • Degree in CS/engineering or related field preferred.
  • Strong understanding of AI-native engineering and production tooling.

Responsibilities

  • Develop the agent itself: loop, harness, and control flow, including subagents and recovery.
  • Engineer context: decide what enters the context window and how to maintain coherence.
  • Design tools for the agent with clear interfaces covering orchestration, scheduling, data capture, and developer tooling.
  • Give the agent memory and state persistence for learning from prior work.
  • Implement permissions and sandboxing for agent actions and human approvals.
  • Defend the agent against prompt injection with auditability and data isolation.
  • Evaluate end-to-end on real tasks and debug traces to improve reliability.
  • Adapt the harness as models improve and remove unnecessary scaffolding.
  • Run an AI-first development loop with bounded engineering and agent harness maintenance.
  • Measure workflow throughput, defect rate, and review cost to raise quality.

Skills

AI-native engineering
Production agents
Context engineering
Agent security
Tool & API design
Production engineering

Education

Bachelor's degree in Computer Science or Engineering

Tools

LangGraph
Databricks
Power BI
Sigma
Spotfire

Job description

Our Why At Dotmatics

At Dotmatics, a Siemens company, we believe science, data, and decision-making must be deeply intertwined for innovation to thrive. Our Portfolio includes Luma, LumaLab Connect, ELN Platform, Graphpad Prism, Geneious, SnapGene, Protein Metrics, OMIQ, FCS Express, LabArchives, NQuery, EasyPanel, SoftGenetics and Virscidian.

We have a vision for a new Lab of the Future that will change the future of scientific research.

We have created the world’s most comprehensive digital science platform – best-of-breed software applications already used by more than 2 million scientists, together in a single ecosystem united by a powerful, flexible enterprise data platform. This is not flat data buried away in digital graveyards. This is dynamic, multi-dimensional decision-making.

Scientific enterprises need a new level of effectiveness to achieve tomorrow’s breakthroughs. Illness will not wait. The biosphere will not wait. We are tireless in our vision, because the time for innovation is now.

Shaping the Future of Science At Dotmatics

Our global team of more than 800 colleagues are dedicated to supporting our customers in over 180 countries. Together, with our scientific community of users, we accelerate scientific innovation in order to make the world a healthier, cleaner, and safer place to live.

You’ll join a collaborative, global team pushing the boundaries of scientific innovation. Your ideas and efforts will have a tangible impact, accelerating scientific progress and discovery. We offer a dynamic, remote-friendly environment that fosters high integrity and collaboration, empowering you to excel. Dotmatics is a company built by scientists, for scientists. Combined, we are now the world’s largest cloud-based scientific research R&D platform. We need your help to keep growing and pioneering the future.

We are Science Driven. We are Customer Centric. We are Better Together.
What do we need

We are looking for an experienced and highly skilled Software Engineer (Agentic AI), to build the AI agent at the core of Dotmatics Luma platform. You will own the agent end to end: how it reasons, which tools it uses, what it remembers, how it recovers from failure, and how we know it is working. You will work in a small, high-trust engineering team alongside Product, scientists, and the wider Dotmatics organisation.

This is also an AI-native engineering role. Your success won’t be measured by how many lines of code you write. It will come from how well you decompose work for coding agents, give them the right context, tools, and constraints, verify their output with tests and review, and ship production software faster than a traditional senior engineer without lowering the quality bar. Coding agents are your default path for implementation, and you stay accountable for architecture, correctness, security, and review.

We want someone who thinks like the engineers who build frontier AI products: rigorous about quality, curious about how agents fail, and quick to adapt as models improve. You use AI tools daily to build AI tools, and you ship agents that work in production, not just in demos.

In this role you will get to
  • Develop the agent itself: the loop, harness, and control flow connecting the model, tools, and state, including subagents, long-running tasks, checkpointing, and recovery.
  • Practice context engineering: decide what goes into the context window, when to compact or summarize, and how to keep the agent coherent over long-running experiments.
  • Design tools for the agent, with clear interfaces and descriptions, covering instrument orchestration, scheduling, data capture, and developer tooling such as GitHub, repositories, CI/CD, and workflows.
  • Give the agent memory and state persistence so it learns from and builds on earlier work.
  • Implement permissions and sandboxing that define what the agent can do on its own, what needs human approval, and how mistakes are contained.
  • Defend the agent against prompt injection and untrusted content, with auditability and data isolation suited to regulated environments.
  • Evaluate the agent end-to-end on real multi-step tasks, then debug its behavior by reading traces and finding root causes, fixing the harness, tools, or prompts to improve reliability, tool-use accuracy, cost, and latency.
  • Adapt the harness as models improve, and remove scaffolding that is no longer needed.
  • Run an AI-first development loop (scope, plan, delegate to coding agents, verify, ship), preferring agent execution over hand-writing whenever quality holds, and build and maintain the team’s agent harness for development itself (project memory, skills, hooks, MCP, CI checks) so agents can safely do bounded engineering work.
  • Measure and improve that workflow through throughput, defect rate, and review cost, and coach others on AI-native practices to raise the team’s bar for agent-driven delivery
  • Set up the architecture and infrastructure to run the agent reliably, and manage configuration, environments, and secrets
  • Deliver the services and interfaces around the agent in Python, Node.js/TypeScript, and React, including streaming output and extension points such as MCP

We are looking for people who have around 10 years of experience in software engineering, including hands‑on experience building LLM-powered agents in production. Ideally you will have a degree or higher education in Computer Science, Engineering, or a related technical field, and an interest in life sciences, lab instrumentation, or automation.

The Key Skills we are looking for:
  • AI-native engineering: autonomous coding agents (Cursor, Claude Code, Codex, or equivalent) as the primary way you build.
  • Production agents: at least one LLM-powered agent shipped to real users, handling multi-step tool use, error recovery, and long-running tasks.
  • Context engineering, memory, and retrieval: a long-running LLM application where you can explain what went into the window, when it was compacted, and how coherence and retrieval quality (RAG, vector indexes, reranking) were measured.
  • Agent security: permissions, sandboxing, human approval gates, prompt injection defenses, and audit logging, tested against adversarial inputs.
  • Tool and API design for models: tools or MCP servers built for model use, with tool-selection and call accuracy measured.
  • Production engineering: Python with type checking, automated tests, and packaging in CI, plus Node.js/TypeScript and React services and interfaces, including streaming output, with monitoring, tracing, and managed configuration and secrets.
You may also have:
  • Experience with agent frameworks such as LangGraph, or building custom harnesses from scratch.
  • Working knowledge of Databricks and BI tools (Sigma, Power BI, Spotfire).
  • Observability for LLM systems (tracing, cost and latency monitoring).
  • Fine-tuning, prompt optimization, or model evaluation experience.
  • Authored skills, hooks, or MCP servers that made agent-driven delivery repeatable for a team.
We are open to speaking to candidates with more or less experience than listed
The compensation for different levels can be discussed with your recruiter
Total Rewards

Dotmatics utilises a national market-based approach to base pay benchmarking and pay band development. The candidate’s final starting pay is based on job-related skills, experience, job specific qualifications & location. In addition to base salary, Dotmatics has implemented a total rewards strategy, which is the combination of compensation, benefits and recognition.

Certain positions are also eligible for variable pay; your recruiter will discuss the full compensation package details.

Other Total Rewards Offered
  • Medical, Dental, Vision, Insurance
  • Health Spending Accounts
  • Wellness Benefits (Mental Health Apps and Fitness Perks)
  • Company-paid Life and Disability Insurance
  • 401k Retirement Plan (with 4% company match; immediate vesting)
  • Flexible Time off Plan (for US exempt employees)

This is the range that we, in good faith, believe is the range of possible compensation for this role at the time of this posting. We may ultimately pay more or less than the posted range. This range may be modified in the future.

Base Pay Range

$124,000—$168,000 USD

Research shows us the confidence gap andimposter syndrome can get in the way of meeting outstanding candidates, so

By submitting your application, you agree that Dotmatics may collect your personal data for recruiting, global organization planning, and related purposes. Dotmatics Privacy Notice explains what personal information we may process, where we may process your personal information, our purposes for processing your personal information, and the rights you can exercise over Dotmatics use of your personal information.

Dotmatics is an equal opportunity employer. We are a welcoming place for everyone, and we do our best to make sure all people feel supported and connected at work.

Get your free, confidential resume review.

or drag and drop your file here.

Similar jobs

Similar jobs worth comparing

Senior Full Stack Engineer | Luma
Senior Full Stack Engineer | Luma

Dotmatics Ltd. • United States

Remote
USD 140,000 - 190,000
Senior Full Stack Engineer | Luma
Senior Full Stack Engineer | Luma

Dotmatics Ltd. • Boston (MA)

On-site
USD 140,000 - 190,000
Remote-friendly
Director, Market Growth Strategy, Molecule to Market (Biologics)
Director, Market Growth Strategy, Molecule to Market (Biologics)

Dotmatics Ltd. • United States

Remote
USD 185,000 - 256,000
Medical, Dental, Vision Insurance
Health Spending Accounts
Wellness Benefits
+3
Director, Professional Services (North America)
Director, Professional Services (North America)

Dotmatics Ltd. • United States

Hybrid
USD 168,000 - 228,000
Medical, Dental, Vision Insurance
401k Retirement Plan (4% company match
Flexible Time off
+1
Demand Generation Marketing Manager
Demand Generation Marketing Manager

Dotmatics Ltd. • United States

Remote
USD 90,000 - 110,000
Private Healthcare
Company Pension Plan
Wellness Benefits
Forward Deployed Engineer
Forward Deployed Engineer

Evbrocks • United States

Hybrid
USD 180,000 - 250,000
Equity compensation
Performance bonuses
Health insurance
+2
Ruby on Rails Developer | LabArchives
Ruby on Rails Developer | LabArchives

Openkrill • United States

Remote
USD 82,000 - 140,000
Medical, Dental, Vision Insurance
Health Spending Accounts
Wellness Benefits
+3
Senior Software Engineer / Senior AI Engineer
Senior Software Engineer / Senior AI Engineer

Elsevier • United States

Remote
USD 87,000 - 144,000
Comprehensive Pension Plan
Generous vacation entitlement and sabb
Maternity, Paternity, Adoption and ICF
+5
Senior Software Engineer / Senior AI Engineer
Senior Software Engineer / Senior AI Engineer

RELX International • United States

Remote
USD 90,000 - 135,000
Pension Plan
Generous vacation + sabbatical leave
Family leave (Maternity, Paternity, Ad
+3
Staff / Senior Software Engineer, Agent Engineering
Staff / Senior Software Engineer, Agent Engineering

Australia-Employment • New York (NY)

On-site
USD 185,000 - 235,000
Equity / ownership
Direct access to founders and CTO
Very high technical ownership
+5