Software Engineer

Sanmai; Sunnyvale (CA); On-site; USD 150,000 - 160,000; Full time

Job summary

Sanmai is seeking a Software Engineer to design, build, and evolve the software architecture behind our neurotechnology platform, spanning internal tooling to production-ready application and firmware code. You will own software verification and validation to ensure compliance with medical device standards, collaborating across engineering, clinical, and regulatory teams in multiple locations.

This role offers full-time work based in South San Francisco, CA, with a salary range of

Qualifications

• Leadership in software architecture and implementation.
• Experience driving V&V in ISO 13485.
• Strong proficiency in Python, C++, Qt 6 SDK, and PySide6 with OO design.
• Comfortable across Windows and Linux with build/CI tooling (Make, CMake, Jenkins) and Bash.
• Understanding of Secure Boot (Intel CPUs).
• Knowledge of databases and software design patterns.
• Experience with Jira, Confluence, Git, and XRay.

Responsibilities

• Design and implement scalable applications and firmware meeting performance, safety, and regulatory needs.
• Contribute to system architecture and lead software design reviews.
• Build and maintain internal tools that streamline operations.
• Own software V&V activities, incl. white-box testing per ISO 13485.
• Collaborate with quality/regulatory teams to support audits and filings.
• Work in an agile process with cross-functional teams.

Skills

Python

C++

Qt 6

PySide6

Windows

Linux

Make

CMake

Jenkins

Bash scripting

PyTest

Secure Boot

Databases

Design patterns

Jira

Confluence

Git

XRay

Rust

ML frameworks

CUDA/OpenCL

Ubuntu customization

Libvirt

Verilog

Communication

Autonomy

Leadership

Education

Bachelor's in Computer Engineering/CS

Master's preferred

Tools

Qt 6 SDK

PySide6

Job description

Sanmai is a Public Benefit Corporation advancing breakthrough neurotechnology through clinical expertise and AI-enabled precision medical devices. Our flagship technology uses focused ultrasound to open a new path in neurotherapeutics — helping people with mental health and neurological conditions find the relief they need. We're a mission-driven team that pairs scientific rigor with real human impact.

The Role

We're looking for a Software Engineer to help design, build, and evolve the software architecture behind our neurotechnology platform — from internal tooling to production-ready application and firmware code. You'll also own software verification and validation to ensure compliance with medical device standards, working cross-functionally with engineering, clinical, and regulatory teams across multiple locations. This is a rare chance to shape the software direction of a company working at the frontier of neuroscience, AI, and mental health.

What You'll Do

• Design and implement scalable applications, and write application and firmware code that meets performance, safety, and regulatory requirements


• Contribute to system architecture and lead software design reviews


• Build and maintain internal tools that streamline operations


• Own software V&V activities, including white-box testing, in compliance with ISO 13485


• Partner with quality and regulatory teams to support audits and filings


• Work in an agile process alongside cross-functional teams

What You Should Have

• Demonstrated leadership in software architecture and implementation


• Experience driving software V&V in compliance with ISO 13485


• Advanced proficiency in Python, C++, Qt 6 SDK, and PySide6, with solid object-oriented design


• Comfortable across Windows and Linux, with build and CI tooling (Make, CMake, Jenkins), Bash scripting, and Python unit testing (PyTest/unittest)


• Understanding of Secure Boot (Intel CPUs)


• Strong knowledge of database systems and software design patterns


• Proficiency with Jira, Confluence, Git, and XRay


• Bachelor's in Computer Engineering, Computer Science, or related field (Master's preferred)


• Nice to have: 5+ years developing for regulated medical devices, 5+ years with Rust, ML frameworks (PyTorch/TensorFlow), CUDA/OpenCL, Ubuntu customization, Libvirt or Xen, and Verilog


• Comfortable with high autonomy in a fast-moving startup and skilled at communicating complexity to technical and non-technical audiences

What You'll Achieve

You’ll design and scale the software platform behind our flagship neurotherapeutic device, lead the V&V processes that support FDA submissions and international approvals, and help bridge neuroscience, software, and user experience into one coherent technical vision.

Full-time, based in South San Francisco, CA. Salary range: $150,000–$160,000/year.