Smart Manufacturing Execution Lead

GlaxoSmithKline; United States; On-site; USD 150,000 - 190,000; Full time

Job summary

GlaxoSmithKline in United States is seeking a Senior Smart Manufacturing Execution Lead to drive the global strategy across the GSC network, delivering data-to-value outcomes through Industry 4.0 and advanced analytics.

You will collaborate with GPS, Manufacturing, Quality, NPI/CMC, Supply Chain, Engineering/Automation, Digital/Tech, and external partners to scale solutions that improve productivity and accelerate medicines delivery.

Qualifications

• Bachelor's degree in Science, Engineering, Advanced Technology, Automation, Data Science, AI, or related field.
• 6+ years delivering complex, cross-functional transformation initiatives in regulated manufacturing.
• Experience with full project life cycle from business case to BAU.
• Strong knowledge of manufacturing operations (MES/eBR, OT/SCADA/DCS, cloud/edge).
• Proven application of analytics, AI to manufacturing and/or supply chain problems.
• Experience leading multi-site/global programs with external suppliers.
• Background in continuous improvement, Six Sigma and/or lean manufacturing.

Responsibilities

• Execute the Smart Manufacturing strategy with a multi-year, value-driven roadmap.
• Lead site-level value identification and prioritization using a data-driven approach.
• Deliver end-to-end Industry 4.0 solutions in partnership with global and site teams.
• Improve data availability and contextualization for decision-making and optimization.
• Build cross-functional delivery teams to design, pilot, scale, and embed solutions.
• Define global standards for design, validation, data integrity, cybersecurity, and supplier delivery.
• Own stakeholder engagement, align priorities, and drive adoption of new capabilities.
• Ensure benefits realization with KPIs and governance reporting.
• Develop digital fluency through training and knowledge transfer.
• Manage external partners to deliver outcomes on time and within scope.

Skills

Cross-functional leadership

Digital analytics

AI in manufacturing

Communication

Change management

Problem solving

Education

Bachelor's degree

Tools

MES/eBR

SCADA/DCS

IT/OT integration

AI/ML in manufacturing

Job description

Position Summary

The Smart Manufacturing Execution Lead is a global role accountable for executing the Smart Manufacturing strategy across the GSC network, accelerating 'data to value' through Industry 4.0 capabilities and advanced analytics/AI.

The role will support identified GSC manufacturing sites and functions as prioritized by SM wave delivery and business value impact.

The role partners with GPS, Manufacturing, Quality, NPI/CMC, Supply Chain, Engineering/Automation, Digital/Tech, Enterprise AI and external partners to identify opportunities, prioritize value, and deliver scalable solutions that deliver business impact and simplify operations across our global supply chain.

The role will help to accelerate delivery of the Smart Manufacturing vision of a connected, predictive, agile supply chain, leveraging technology, data and AI to transform work, maximize productivity, enhance performance and accelerate medicines and vaccines to patients.

Responsibilities

• Execute the Smart Manufacturing strategy and translate the Smart Manufacturing vision into an accelerated outcome-based multi-year roadmap, aligned to GSC objectives and governance.


• Lead value identification and prioritization at key sites: assess digital maturity, diagnose performance opportunities, quantify benefit ranges, and select projects using a value-driven approach.


• Deliver high impact Industry 4.0 solutions end-to-end (e.g. IT/OT integration, manufacturing data intelligence, connected worker solutions, MES/eBR, SCADA/DCS integration, process analytical technology, advanced analytics, lab automation, model predictive control and AI) in partnership with global and site teams.


• Accelerate 'data to value' by improving data availability, contextualization and consumption models so that data is immediately usable from multiple sources for decision-making, monitoring, optimization and advanced control.


• Build and lead cross-functional delivery matrix teams (Ops, Quality, MSAT, Supply Chain, Engineering, Automation, Digital/Tech) to design, pilot, scale and embed solutions into standard ways of working.


• Define and maintain global standards and playbooks for solution design, validation, data integrity, cybersecurity, and supplier delivery to ensure compliant, repeatable deployments and in alignment with global stage gate process expectations.


• Own stakeholder engagement and influence: partner with senior leaders and front-line teams to align priorities, remove barriers, enable change and drive adoption; role model enterprise mindset, collaborative leadership and GSK behaviors.


• Ensure benefits realization: establish KPIs, track value delivery (e.g., productivity, OEE, yield, lead time, deviations, cost of poor quality), and provide clear reporting and insights to governance forums.


• Develop capability and community: build digital/data fluency through training, coaching and knowledge transfer; strengthen the network's ability to sustain and extend solutions.


• Manage external partners/suppliers to deliver high-quality outcomes on time and within agreed scope, ensuring interoperability with the broader technology landscape.

Basic Qualification

• Bachelor's degree (or equivalent experience) in Science, Engineering, Advanced Technology, Automation, Data Science, AI, or a related discipline.


• 6 years + demonstrated hands on experience delivering complex, cross-functional transformation initiatives that drive value focused innovation and change in a regulated and complex manufacturing environments.


• Experience with full life cycle of projects from business case creation to hyper care/BAU.


• Strong manufacturing operational knowledge (manufacturing operations, process control, MES/eBR, OT/SCADA/DCS, cloud and edge) and ability to work across Quality, Technical/Engineering and Supply Chain interfaces.


• Proven capability in application of advanced analytics, data science, AI to manufacturing and/or supply chain problems (e.g., anomaly detection, predictive monitoring, simulation, optimization, decision support, advanced control).


• Experience leading multi-site / global programs with external supplier reliance, partner delivery and matrix leadership.


• Background experience in continuous improvement, six sigma and/or lean manufacturing initiatives

Preferred Qualification

• Strong stakeholder management and influencing skills at all levels; able to communicate complex technical topics in business terms.


• Value realization and financial acumen: ability to build business cases, define KPIs, and track benefits to outcomes.


• Understanding of data integrity, validation expectations (GxP), ISA-95/ISA-88, cybersecurity frameworks, and compliant digital delivery.


• Knowledge of Quality, NPI/CMC and Supply Chain processes and the data/decision flows between them.


• Familiarity with MLOps practices and the challenges of deploying and governing ML models in regulated manufacturing environments.


• Experience of primary and secondary manufacturing in small and/or large molecule facilities


• Excellent communication skills

If you require an accommodation or other assistance to apply for a job at GSK/ViiV Healthcare, please submit a request to HR via the Service Portal.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

This Position Description is to provide a framework for job understanding between employee and manager. It may not cover or contain the full listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice and at the discretion of the management of the Company. The position description is not used in the assignment or assessment of any GSK level or grade used in the Job Evaluation Process.

Compensation Grade: 5

Eligible for Employee Referral Bonus: Yes