SF-based Staff Engineer for Autonomous Scientific Discovery

Autopoiesis Sciences; San Francisco (CA); On-site; USD 180,000 - 260,000; Full time

Benefits offered by this job

Equity

Benefits

Job summary

Autopoiesis Sciences, Inc. in San Francisco is seeking a Member of Technical Staff to advance autonomous scientific discovery through experimental design, training-stack development, and creation of models that push beyond current limits.

You will blend research and engineering, form hypotheses, implement tests, and iteratively improve systems with a focus on scalable, reliable results. The role supports a close collaboration with the founding team.

Qualifications

• Experience with pretraining, large-scale training, or reinforcement learning.
• A track record of research contributions, shipped models, or systems others relied on.
• Familiarity with scientific domains or a genuine curiosity about them.
• Early-stage startup experience, or the temperament for it.

Responsibilities

• Drive research on autonomous scientific discovery, from pretraining to the environments and reward signals that teach models to reason like scientists.
• Design and run experiments end to end, forming hypotheses, building what tests them, and following the evidence.
• Build and improve the training stack, making runs faster, more reliable, and more ambitious.
• Turn research into real capability, closing the gap between a promising result and a model that works.
• Work closely with researchers and the founding team on the hardest parts of the core problem.

Skills

Pretraining

Large-scale training

Reinforcement learning

Research contributions

Job description

Autopoiesis Sciences, Inc. in San Francisco is seeking a Member of Technical Staff to advance autonomous scientific discovery through experimental design, training-stack development, and creation of models that push beyond current limits.

You will blend research and engineering, form hypotheses, implement tests, and iteratively improve systems with a focus on scalable, reliable results. The role supports a close collaboration with the founding team.