Senior Yeast Strain Engineer: Genome Editing & HTS

ADM; Decatur (IL); On-site; USD 120,000 - 160,000; Full time

Job summary

ADM Cell Engineering is seeking an experienced synthetic biologist to design, build and test yeast strains for a high-impact project supporting ADM BioSolutions sustainable materials. You will combine genome editing, molecular biology and phenotypic screens to develop strains with improved fermentation performance.

The role requires Ph.D. or MSc with industry experience, strong collaboration across teams, and proficiency in data analysis and bioinformatics.

Qualifications

• Ph.D. or MSc with relevant experience in yeast/microbial genetics, cell biology or physiology.
• Experience with 96-well plate methods for cloning or biochemical assays.
• Ability to interpret genetic, molecular biology and biochemistry data.
• Familiarity with Python or R for bioinformatics data analysis.
• Knowledge of bio-based production and fermentation KPIs.
• Ability to generate, organize and interpret large datasets.

Responsibilities

• Design and build yeast strains containing heterologous pathways or loss-of-function mutations.
• Apply genome editing technologies to efficiently create new strains.
• Analyze data to link genotype to phenotype and report findings.
• Optimize strain engineering methods to accelerate DBTL cycles.
• Interpret NGS data (DNA-seq, RNA-seq).
• Collaborate with automation scientists to transfer bench work to high-throughput platforms.
• Maintain detailed notes in Benchling ELN/LIMS for data sharing.
• Contribute to a team-oriented, safe work environment.

Skills

Yeast genetics

Bioinformatics

Data analysis

Team collaboration

Communication skills

High-throughput screening

Molecular cloning

Genome editing

Education

Ph.D. in molecular biology, biochemistry, biotechnology (or related field)

M.Sc. degree with 5+ years industry experience

Tools

Benchling ELN/LIMS

Job description

ADM Cell Engineering is seeking an experienced synthetic biologist to design, build and test yeast strains for a high-impact project supporting ADM BioSolutions sustainable materials. You will combine genome editing, molecular biology and phenotypic screens to develop strains with improved fermentation performance.

The role requires Ph.D. or MSc with industry experience, strong collaboration across teams, and proficiency in data analysis and bioinformatics.