Senior Validation Architect – CQV & Compliance Leadership

Regulatory Jobs; California; On-site; USD 139,000 - 208,000; Full time

Job summary

AstraZeneca in Tarzana, California seeks an Associate Director – Validation to lead the site validation program across facilities and equipment, ensuring cGMP compliance and project success. You will guide CQV activities, manage complex validation projects, and coordinate with QA, operations, and engineering globally.

The role requires extensive GMP knowledge, regulatory expertise, and strong leadership. Expect occasional travel with competitive compensation, a comprehensive benefits package,

Qualifications

• Bachelor's degree in Engineering or life sciences; Master’s preferred.
• 10–12 years of validation program management experience in pharma.
• Extensive knowledge of GMP, FDA regulations, and compliance.
• Proven experience leading complex validation, asset life-cycle management, and capital projects.
• Strong project management with budgeting and scheduling skills.
• Excellent analytical, problem-solving, and communication abilities.

Responsibilities

• Lead site validation strategy and program aligning to cGMP and global standards.
• Collaborate cross-functionally to drive validation strategy site-wide.
• Oversee CQV deliverables for facilities and equipment.
• Ensure qualification and validation activities meet regulatory requirements.
• Manage validation documentation and reporting within EQV.

Skills

Leadership

Project management

Regulatory compliance

GMP knowledge

Communication

Problem solving

Strategic thinking

Education

Bachelor's degree in Engineering or related life sciences

Master’s degree preferred

Job description

AstraZeneca in Tarzana, California seeks an Associate Director – Validation to lead the site validation program across facilities and equipment, ensuring cGMP compliance and project success. You will guide CQV activities, manage complex validation projects, and coordinate with QA, operations, and engineering globally.

The role requires extensive GMP knowledge, regulatory expertise, and strong leadership. Expect occasional travel with competitive compensation, a comprehensive benefits package,