Immuno-Oncology Translational Scientist (On-Site, Equity)

MassBio; Cambridge (MA); On-site; USD 115,000 - 135,000; Full time

Benefits offered by this job

Company-paid health insurance

Equity participation

Comprehensive employee benefits

Paid time off and company holidays

Professional growth opportunities

Job summary

XenImmune Therapeutics, Inc. in Cambridge, MA is seeking a hands-on Scientist to support the development of novel biologic therapeutics in translational biology and immuno-oncology. This full-time, on-site role requires no travel.

The successful candidate will design and execute experiments, analyze data, maintain meticulous records, and present findings to colleagues and leadership. Expertise in flow cytometry, mammalian cell culture, cell-based assays, and handling human samples is essential.

Qualifications

• BS or MS degree in biology, immunology, biochemistry, molecular biology, biotechnology, biomedical sciences, or a related field.
• 4+ years with BS or 2+ years with MS; equivalent combinations considered.
• Hands-on flow cytometry experience with FlowJo.
• Mammalian tissue culture and cell-line experience.
• Experience with human biological samples.
• Ability to design, execute, and troubleshoot experiments.
• Strong organizational and data integrity skills.
• Ability to present results clearly to colleagues and management.

Responsibilities

• Design, execute, analyze, and document cell-based and biochemical experiments supporting therapeutic development.
• Perform multiparameter flow cytometry, including sample preparation, staining, acquisition, gating, and analysis using FlowJo.
• Maintain and manipulate mammalian cell lines using rigorous sterile/aseptic technique.
• Conduct experiments with human biological samples, including primary cells, blood-derived materials, serum, and plasma.
• Develop and perform cell-based bioassays, including viability, cytotoxicity, and cell-death assays.
• Perform ELISA and other plate-based assays, including luminescence-based readouts.
• Measure cytokines and analyze cytokine-response data.
• Perform basic microscopy and imaging.
• Support characterization of biologic therapeutics and mechanism-of-action studies.
• Organize, graph, analyze, and interpret experimental datasets using appropriate statistical and graphical methods.
• Use productivity and AI-enabled tools, including ChatGPT, appropriately for research, data organization, literature analysis, and communication.
• Maintain complete, accurate, and traceable laboratory records.
• Prepare experimental summaries, figures, presentations, and reports.
• Present results and conclusions clearly to scientists and company management.
• Collaborate with internal scientists and external research partners.
• Contribute to experimental planning, troubleshooting, assay optimization, and method development.

Skills

Flow cytometry

Mammalian cell culture

Cell-based assays

Data analysis

Communication skills

Education

BS or MS degree in biology, immunology, biochemistry, molecular biology, biotechnology, biomedical sciences, or a related field

Tools

FlowJo

Job description

XenImmune Therapeutics, Inc. in Cambridge, MA is seeking a hands-on Scientist to support the development of novel biologic therapeutics in translational biology and immuno-oncology. This full-time, on-site role requires no travel.

The successful candidate will design and execute experiments, analyze data, maintain meticulous records, and present findings to colleagues and leadership. Expertise in flow cytometry, mammalian cell culture, cell-based assays, and handling human samples is essential.