Senior Toxicologist (REMOTE ROLE)

ICF; Durham (NC); Remote; USD 81,000 - 139,000; Full time

Job summary

ICF is seeking a Senior Toxicologist to join our Health Science Portfolio, supporting federal agencies with hazard studies and human health risk assessments for environmental pollutants. The role involves integrating molecular biology, NAMs data, and MOA frameworks to inform weight-of-evidence conclusions.

You will lead multiple projects, mentor staff, draft protocols and reports, and collaborate with cross-functional teams of toxicologists, biologists, epidemiologists, and statisticians in a

Qualifications

• Ph.D. with 5+ years experience or M.S. with 10+ years.
• Experience with hazard assessment and risk assessment.
• Strong communication and leadership skills.

Responsibilities

• Lead multiple projects in toxicology data analysis and risk assessment.
• Develop toxicology reports with methods, results, and discussion.
• Draft protocols, reports, manuscripts, and proposals.
• Collaborate with toxicologists, biologists, epidemiologists, and statisticians.
• Perform literature screening, data extraction, and dose–response analysis.
• Mentor and train junior staff.

Skills

Communication skills

Quantitative skills

NAMs knowledge

Systematic review

Project management

Staff leadership

Problem solving

Detail oriented

Multitasking

Education

Ph.D. in toxicology or related field

M.S. in toxicology or related field

Job description

Senior Toxicologist

To support ICF’s dynamic growth and expanding client base, we are seeking a Senior Toxicologist to work in our Health Science Portfolio. This group of 100+ science professionals provide toxicology, hazard assessment, epidemiology, risk assessment, exposure assessment, environmental modeling, and related support that addresses the full spectrum of potentially hazardous agents, including chemicals and microbes. We specialize in identifying and quantifying the effects of environmental pollutants—including metals, pesticides, industrial chemicals, and volatile organic compounds—on human health and the environment.

Description

The Senior Toxicologist’s project work would support federal agencies (such as U.S. EPA and NIEHS) in the design, conduct, and reporting of hazard studies and human health risk assessments for environmental pollutants. In particular, the successful candidate will provide leadership in the identification, interpretation, and integration of molecular biology, mechanistic toxicology, and new approach methodologies (NAMs) data to support hazard identification, mode-of-action analyses, systematic review, and human health risk assessments. The role will involve evaluating diverse evidence streams including gene expression, -omics, cellular and molecular assays, pathway-based data, and adverse outcome pathway (AOP) frameworks.

Location

Remote

What You’ll Do

• Project management and technical leadership activities on multiple projects concurrently involving toxicology data, systematic literature reviews, and risk assessment. Assist in the definition of project scope and objectives and serve as the primary point of contact for client and internal project teams.
• Toxicological report development, including writing methods, results, and discussion sections, reviewing toxicological conclusions based on the test results, and synthesizing findings into a weight of evidence analysis.
• Draft protocol and guidance documents, toxicological reports, manuscripts, project descriptions, and proposals.
• Collaborate with multidisciplinary teams of toxicologists, biologists, epidemiologists, and statisticians to address complex scientific and regulatory questions.
• Toxicology systematic review tasks including literature screening, study quality evaluation, study data extraction, dose-response analysis, incorporation of NAMs and mechanistic data, and data synthesis.
• Supervise, mentor, and train junior- and mid-level staff.

Basic Qualifications

• Ph.D. in toxicology, pharmacology, environmental science, or related subject with 5+ years of experience in academic, industry, regulatory, or consulting fields.
• OR Master’s degree in toxicology, pharmacology, environmental science, or related subject with 10+ years of experience.

Preferred Qualifications

• Strong working knowledge of mechanistic toxicology and molecular biology
• Experience integrating mechanistic, animal, and human evidence into a weight-of-evidence evaluation
• Experience with mode of action and adverse outcome pathway (MOA and AOP) concepts, frameworks, and analyses
• Experience evaluating molecular, cellular, and mechanistic data including transcriptomics, proteomics, metabolomics, and high-throughput screening assays
• Experience with endocrine disruptors, PFAS, PAHs, and other emerging contaminants
• Experience in cancer assessment
• Experience with NAMs, molecular biology techniques, and mechanistic data for regulatory decision-making
• Experience with systematic literature review
• Strong quantitative skills with experience in dose-response analysis, benchmark dose modeling, pathway enrichment analyses, or similar modeling experience
• Strong written and oral communication skills
• Proactive and problem-solving approach to challenges
• Experience/familiarity with government programs
• Excellent organizational skills and attention to detail
• Ability to prioritize, multi-task, and work under strict deadlines in a fast-paced environment
• Experience with project management and staff leadership
• Demonstrated ability to formulate and execute technical approaches to solving scientific questions

Working at ICF

ICF is a global advisory and technology services provider, but we’re not your typical consultants. We combine unmatched expertise with cutting-edge technology to help clients solve their most complex challenges, navigate change, and shape the future. We can only solve the world's toughest challenges by building a workplace that allows everyone to thrive. We are an equal opportunity employer. Together, our employees are empowered to share their expertise and collaborate with others to achieve personal and professional goals. For more information, please read our EEO policy. We will consider for employment qualified applicants with arrest and conviction records. Reasonable Accommodations are available, including, but not limited to, for disabled veterans, individuals with disabilities, and individuals with sincerely held religious beliefs, in all phases of the application and employment process. To request an accommodation, please email [e-mail] and we will be happy to assist. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodations. Read more about workplace discrimination rights or our benefit offerings which are included in the Transparency in (Benefits) Coverage Act.

Candidate AI Usage Policy

At ICF, we are committed to ensuring a fair interview process for all candidates based on their own skills and knowledge. As part of this commitment, the use of artificial intelligence (AI) tools to generate or assist with responses during interviews (whether in-person or virtual) is not permitted. This policy is in place to maintain the integrity and authenticity of the interview process. However, we understand that some candidates may require accommodation that involves the use of AI. If such an accommodation is needed, candidates are instructed to contact us in advance at [e-mail]. We are dedicated to providing the necessary support to ensure that all candidates have an equal opportunity to succeed.

Pay Range

The pay range for this position based on full-time employment is:

$81,499.00 - $138,549.00

Nationwide Remote Office (US99)