Senior Toxicologist (REMOTE ROLE)

ICF Olson; United States; Remote; USD 81,000 - 139,000; Full time

Job summary

ICF is seeking a Senior Toxicologist to join its Health Science Portfolio and drive toxicology and risk assessment efforts for environmental pollutants. The role emphasizes leadership in integrating molecular biology, NAMs data, and MOA/AOP concepts across projects, including hazard identification and weight‑of‑evidence analyses.

The successful candidate will work with federal agencies and cross-functional teams, manage multiple studies, and mentor junior staff while contributing to high‑impact

Qualifications

• Ph.D. with 5+ years of experience in toxicology, pharmacology, environmental science, or related field.
• Master’s with 10+ years of experience in toxicology, pharmacology, environmental science, or related field.
• Strong working knowledge of mechanistic toxicology and molecular biology.
• Experience integrating mechanistic, animal, and human evidence into a weight-of-evidence evaluation.
• Experience with MOA and adverse outcome pathway (MOA and AOP) concepts, frameworks, and analyses.
• Experience evaluating molecular, cellular, and mechanistic data including transcriptomics, proteomics, metabolomics, and high-throughput screening assays.
• Experience with NAMs, molecular biology techniques, and mechanistic data for regulatory decision‑making.
• Experience with systematic literature review.
• Strong quantitative skills with dose‑response analysis, benchmark dose modeling, pathway enrichment analyses, or similar modeling experience.
• Strong written and oral communication skills.
• Proactive problem-solving approach and ability to prioritize in fast-paced environments.
• Experience with government programs and staff leadership.

Responsibilities

• Project management and technical leadership on multiple toxicology projects.
• Assist in defining project scope and serve as primary client contact.
• Toxicological report development, including methods, results, and discussion sections.
• Draft protocols, toxicological reports, manuscripts, and proposals.
• Collaborate with multidisciplinary teams to address complex questions.
• Toxicology systematic review tasks including literature screening and data extraction.
• Supervise, mentor, and train junior- and mid-level staff.

Skills

Mechanistic toxicology

Molecular biology

MOA/AOP concepts

Transcriptomics

Dose-response analysis

Data synthesis

Project management

Leadership

Education

Ph.D. in toxicology, pharmacology, environmental science, or related subject

Master’s degree in toxicology, pharmacology, environmental science, or related subject

Job description

SENIOR TOXICOLOGIST

To support ICF’s dynamic growth and expanding client base, we are seeking a Senior Toxicologist to work in our Health Science Portfolio. This group of 100+ science professionals provide toxicology, hazard assessment, epidemiology, risk assessment, exposure assessment, environmental modeling, and related support that addresses the full spectrum of potentially hazardous agents, including chemicals and microbes. We specialize in identifying and quantifying the effects of environmental pollutants—including metals, pesticides, industrial chemicals, and volatile organic compounds—on human health and the environment. The Senior Toxicologist’s project work would support federal agencies (such as U.S. EPA and NIEHS) in the design, conduct, and reporting of hazard studies and human health risk assessments for environmental pollutants. In particular, the successful candidate will provide leadership in the identification, interpretation, and integration of molecular biology, mechanistic toxicology, and new approach methodologies (NAMs) data to support hazard identification, mode‑of‑action analyses, systematic review, and human health risk assessments. The role will involve evaluating diverse evidence streams including gene expression, -omics, cellular and molecular assays, pathway‑based data, and adverse outcome pathway (AOP) frameworks.

Location

Remote

What you’ll do

• Project management and technical leadership activities on multiple projects concurrently involving toxicology data, systematic literature reviews, and risk assessment.
• Assist in the definition of project scope and objectives and serve as the primary point of contact for client and internal project teams.
• Toxicological report development, including writing methods, results, and discussion sections, reviewing toxicological conclusions based on the test results, and synthesizing findings into a weight of evidence analysis.
• Draft protocol and guidance documents, toxicological reports, manuscripts, project descriptions, and proposals.
• Collaborate with multidisciplinary teams of toxicologists, biologists, epidemiologists, and statisticians to address complex scientific and regulatory questions.
• Toxicology systematic review tasks including literature screening, study quality evaluation, study data extraction, dose‑response analysis, incorporation of NAMs and mechanistic data, and data synthesis.
• Supervise, mentor, and train junior- and mid-level staff.

Basic Qualifications

• Ph.D. in toxicology, pharmacology, environmental science, or related subject with 5+ years of experience in academic, industry, regulatory, or consulting fields.
• OR Master’s degree in toxicology, pharmacology, environmental science, or related subject with 10+ years of experience.

Preferred Qualifications

• Strong working knowledge of mechanistic toxicology and molecular biology
• Experience integrating mechanistic, animal, and human evidence into a weight‑of‑evidence evaluation
• Experience with mode of action and adverse outcome pathway (MOA and AOP) concepts, frameworks, and analyses
• Experience evaluating molecular, cellular, and mechanistic data including transcriptomics, proteomics, metabolomics, and high‑throughput screening assays
• Experience with endocrine disruptors, PFAS, PAHs, and other emerging contaminants
• Experience in cancer assessment
• Experience with NAMs, molecular biology techniques, and mechanistic data for regulatory decision‑making
• Experience with systematic literature review
• Strong quantitative skills with experience in dose‑response analysis, benchmark dose modeling, pathway enrichment analyses, or similar modeling experience
• Strong written and oral communication skills
• Proactive and problem‑solving approach to challenges
• Experience/familiarity with government programs
• Excellent organizational skills and attention to detail
• Ability to prioritize, multi‑task, and work under strict deadlines in a fast‑paced environment
• Experience with project management and staff leadership
• Demonstrated ability to formulate and execute technical approaches to solving scientific questions

We are an equal opportunity employer. Together, our employees are empowered to share their expertise and collaborate with others to achieve personal and professional goals. For more information, please read our EEO policy. We will consider for employment qualified applicants with arrest and conviction records.

Applicants needing an accommodation for disability or religious purposes in connection with the application process should contact [e-mail] for assistance.

Pay Range - There are multiple factors that are considered in determining final pay for a position, including, but not limited to, relevant work experience, skills, certifications and competencies that align to the specified role, geographic location, education and certifications as well as contract provisions regarding labor categories that are specific to the position. The pay range for this position based on full‑time employment is: $81,499.00 - $138,549.00 Nationwide Remote Office (US99)

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About ICF ICF is a global consulting and technology services company with approximately 9,000 employees, but we are not your typical consultants. At ICF, business analysts and policy specialists work together with digital strategists, data scientists and creatives. We combine unmatched industry expertise with cutting‑edge engagement capabilities to help organizations solve their most complex challenges. Since 1969, public and private sector clients have worked with ICF to navigate change and shape the future. Learn more at icf.com.