Senior Technical Operations Engineer – Reagent Manufacturing

Bio-Techne; Minneapolis (MN); On-site; USD 110,000 - 140,000; Full time

Benefits offered by this job

Competitive benefits

401k/ESPP/HSA

Job summary

Scorpion Therapeutics is seeking a Senior Process Engineer – Reagent Manufacturing to strengthen our manufacturing capability by improving robustness, repeatability, and quality of reagent production at the Minneapolis site. You will apply process-engineering expertise to scale, integrate, and optimize liquid handling, mixing, and filtration across platforms.

This onsite role requires collaboration with R&D, Quality, Facilities, and Manufacturing to translate developmental knowledge into

Qualifications

• 3+ years of process-engineering experience in pharma/biopharma/biotech/reagent/diagnostic manufacturing.
• Bachelor’s degree in chemical/biochemical engineering or related field.
• Demonstrated liquid-processing unit operations experience (mixing, formulation, filtration, liquid handling/transfer).
• Experience with equipment selection, process requirements, commissioning/qualification, or troubleshooting.
• Regulated/quality system experience preferred.
• Process/equipment introduction or significant modification experience; cell culture/purification exposure preferred.

Responsibilities

• Lead process-engineering support for prioritized technical gaps; assess overall process capability (materials, equipment, scale, parameters, operating methods, variation, outputs).
• Serve as SME for reagent preparation, liquid handling/transfer, mixing, formulation, and filtration.
• Support mixing scale-up (equipment selection, operating ranges, performance confirmation) and filtration (selection, sizing, operating conditions, compatibility, capacity).
• Assess and improve process/equipment cleanability to support bioburden control.
• Lead technical assessments and engineering studies; define requirements/acceptance criteria and recommend sustainable corrective actions.
• Apply process engineering to cell culture, purification, and related processes as needed.
• Evaluate equipment suitability; support equipment selection/improvements; participate in vendor reviews/testing/commissioning/qualification; troubleshoot equipment–process interactions.
• Support process readiness and implementation for introductions/changes; translate knowledge into manufacturing requirements.
• Partner cross-functionally (R&D, Manufacturing, Quality, Facilities, Engineering, Automation) and communicate risks/study results; capture technical basis to maintain process knowledge.

Skills

Process engineering

Liquid handling

Mixing/formulation

Filtration

Troubleshooting

Education

Bachelor's degree in chemical/biochemical engineering

Tools

Commissioning/Qualification

Job description

Position Summary:

Senior Process Engineer – Reagent Manufacturing provides technical process-engineering expertise to strengthen manufacturing capability—improving robustness, repeatability, quality, and manufacturability of existing processes for reagent manufacturing.

Key Responsibilities:

• Lead process-engineering support for prioritized technical gaps; assess overall process capability (materials, equipment, scale, parameters, operating methods, variation, outputs).


• Serve as SME for reagent preparation, liquid handling/transfer, mixing, formulation, and filtration.


• Support mixing scale-up (equipment selection, operating ranges, performance confirmation) and filtration (selection, sizing, operating conditions, compatibility, capacity).


• Assess and improve process/equipment cleanability to support bioburden control.


• Lead technical assessments and engineering studies; define requirements/acceptance criteria and recommend sustainable corrective actions.


• Apply process engineering to cell culture, purification, and related processes as needed.


• Evaluate equipment suitability; support equipment selection/improvements; participate in vendor reviews/testing/commissioning/qualification; troubleshoot equipment–process interactions.


• Support process readiness and implementation for introductions/changes; translate knowledge into manufacturing requirements.


• Partner cross-functionally (R&D, Manufacturing, Quality, Facilities, Engineering, Automation) and communicate risks/study results; capture technical basis to maintain process knowledge.

Qualifications:

• Bachelor’s degree in engineering (chemical/biochemical preferred).


• 3+ years relevant process-engineering experience (5+ preferred) in pharma/biopharma/biotech/reagent/diagnostic manufacturing.


• Demonstrated liquid-processing unit operations experience (mixing, formulation, filtration, liquid handling/transfer).


• Experience with equipment selection, process requirements, commissioning/qualification, or troubleshooting.


• Regulated/controlled quality system experience preferred.


• Process/equipment introduction or significant modification experience preferred; cell culture/purification exposure preferred.

Skills/Abilities:

Process capability evaluation; cleanable processing/bioburden control; define studies and acceptance criteria; structured problem-solving/root-cause analysis; translate tech transfer needs into operating/equipment requirements; communicate clearly; work across site functions and quality documentation/approval systems; manage multiple priorities.

Benefits (as stated):

• Competitive insurance (medical, dental, vision, life, short/long-term disability, pet, legal/ID shield) and 401k/ESPP/HSA/FSA.

Working Conditions:

Onsite role supporting office, laboratory, and manufacturing activities at the Minneapolis site; controlled environments may require PPE/gowning.