Senior Systems Toxicology Scientist — Omics & Safety Insights

Sanofi Group; New Jersey; Presencial; USD 180.000 - 240.000; Tempo integral

Benefícios oferecidos por esta vaga

Health benefits and wellbeing programs

Parental leave (14 weeks)

Resumo da vaga

Sanofi Group in the United States seeks a Distinguished Scientist, Systems Toxicology to lead omics-based safety assessment and mechanistic interpretation across drug discovery. You will shape analytical workflows, translate questions into integrated analyses, and guide experimental investigations while collaborating with project toxicologists and scientific advisors.

The role requires senior hands-on leadership, communication with senior leaders, and a track record of translating complex data

Qualificações

• Minimum Requirements: MS plus 8 years experience or PhD plus 5 years experience.
• Scientific expertise: Systems Biology, Computational Biology, Bioinformatics, or a related discipline, with extensive research experience and demonstrated independent leadership of complex investigations.
• Technical skills: Deep hands-on expertise in transcriptomics and demonstrated experience integrating multiple molecular or phenotypic data types.
• Computational and statistical capabilities: Strong proficiency in R and/or Python and relevant bioinformatics tools.
• Mechanistic and translational interpretation: Expertise in pathway and network analysis, molecular signatures, and hypothesis generation.
• Drug discovery and safety experience: Substantial experience applying systems approaches to toxicology, safety assessment, or closely related mechanistic research in pharmaceutical or biotechnology settings.
• Strategic mindset: Understanding of how preclinical safety data translates to human safety, ability to translate scientific vision into actionable roadmaps, connect digital toxicology to broader R&D strategy.
• Communication & influence: Ability to communicate complex analyses clearly to experimental scientists, computational specialists, project teams, and senior leaders.

Responsabilidades

• Provide scientific direction for systems toxicology, defining approaches for applying omics and integrative biology to priority safety questions.
• Lead integrated analyses of complex biological datasets, connecting transcriptomics with complementary data such as proteomics, metabolomics, imaging, pathology, and functional assays.
• Generate and prioritize mechanistic hypotheses using pathway analysis, network biology, molecular signatures, and existing biological knowledge.
• Establish reproducible and scalable analytical workflows, spanning data processing, quality assessment, statistical analysis, visualization, and reporting.
• Drive cross-functional investigations across Preclinical Safety, connecting early screening, complex models, and investigative studies with molecular mechanisms.
• Provide scientific leadership across project teams and global functions, working with project toxicologists and scientific advisors to define decision‑relevant questions and communicate integrated findings.
• Demonstrate scientific and portfolio impact, serving as a scientific authority and mentor across the global organization.

Conhecimentos

Systems Biology

Computational Biology

Bioinformatics

R

Python

Formação

MS + 8 years experience

PhD + 5 years experience

Ferramentas

R

Python

Bioinformatics tools

Descrição da vaga

Sanofi Group in the United States seeks a Distinguished Scientist, Systems Toxicology to lead omics-based safety assessment and mechanistic interpretation across drug discovery. You will shape analytical workflows, translate questions into integrated analyses, and guide experimental investigations while collaborating with project toxicologists and scientific advisors.

The role requires senior hands-on leadership, communication with senior leaders, and a track record of translating complex data