Senior Systems Administrator - South San Francisco, California

Slipstream IT, LLC; South San Francisco (CA); On-site; USD 90,000 - 120,000; Full time

Job summary

Slipstream Life Sciences in South San Francisco is seeking a Senior Systems Administrator to provide hands-on IT support across macOS and Windows, manage servers, backups, and scripting, and ensure smooth day-to-day operations for a biotech environment.

You will deploy and support end-user devices, automate routine tasks with PowerShell, Bash, or Python, and collaborate with the IT team to maintain security and documentation.

Qualifications

• Demonstrated proficiency supporting and administering macOS and Windows.
• Hands-on scripting experience (PowerShell, Bash, or Python).
• Experience with backup and storage technologies: Veeam, NAS, and S3.
• Strong troubleshooting, communication, and customer-service skills.
• Able to work on-site full time at the South San Francisco location.

Responsibilities

• Provide on-site IT support across mixed macOS and Windows environments, including hardware, software, and network troubleshooting.
• Administer and maintain server infrastructure, including day-to-day monitoring and maintenance.
• Manage and monitor backup systems, including Veeam, NAS, and S3-based storage.
• Write and maintain scripts to automate routine IT tasks and improve operational efficiency.
• Deploy, configure, and support end-user laptops and desktops.
• Escalate and resolve issues beyond tier-1 support, partnering with the broader IT/infrastructure team.
• Maintain accurate documentation of systems, configurations, and support procedures.

Skills

macOS

Windows

Scripting

Troubleshooting

On-site

Tools

Veeam

NAS

S3

Job description

Are you ready for new challenges and new opportunities?

Join our team!

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At Slipstream Life Sciences we work to streamline IT Support and provide managed solutions with a strategic consulting and global leadership management approach. Our solutions are designed exclusively for emerging pharma and biotech organizations.

Slipstream's industry-leading solutions free clients from the demands of internal IT and allow them to rapidly advance their mission. Led by a leadership team that has been together for over 10 years, you will join a proven team, culture, and strategy to drive innovation within the IT outsourcing industry while developing your skillset with the opportunities for internal growth.

About the Role

Slipstream is seeking a Senior Systems Administrator, hands-on generalist who can support servers, backups, and scripting in addition to day-to-day end-user support across both macOS and Windows environments.

Key Responsibilities

• Provide on-site IT support across mixed macOS and Windows environments, including hardware, software, and network troubleshooting.
• Administer and maintain server infrastructure, including day-to-day monitoring and maintenance.
• Manage and monitor backup systems, including Veeam, NAS, and S3-based storage.
• Write and maintain scripts to automate routine IT tasks and improve operational efficiency.
• Deploy, configure, and support end-user laptops and desktops.
• Escalate and resolve issues beyond tier-1 support, partnering with the broader IT/infrastructure team.
• Maintain accurate documentation of systems, configurations, and support procedures.

Required Qualifications

• Demonstrated proficiency supporting and administering both macOS and Windows.
• Hands-on scripting experience (e.g., PowerShell, Bash, or Python).
• Experience with backup and storage technologies: Veeam, NAS, and S3.
• Strong troubleshooting, communication, and customer-service skills.
• Able to work on-site full time at the South San Francisco location.

Preferred Qualifications

• Prior IT support experience in a life sciences, biotech, or pharma environment.
• Experience operating in security- or compliance-conscious IT environments.
• Relevant certifications (Microsoft, Apple, Veeam, or similar) a plus.
• Life insurance/LTD
• Discretionary PTO

Slipstream is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation or identity, national origin, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. Slipstream makes hiring decisions based solely on qualifications, merit, and business needs at the time.

This job description may not be inclusive of all assigned duties, responsibilities, or aspects of the job described, and may be amended at any time at the sole discretion of the Employer.