Senior Staff Systems Engineer

Dexcom; California (MO); Hybrid; USD 149,000 - 248,000; Full time

Benefits offered by this job

Comprehensive benefits program

Growth opportunities on a global scale

Tuition reimbursement

Hybrid workplace option

Job summary

Dexcom is seeking a Senior Staff Systems Engineer to lead architecture for its connected CGM ecosystem, spanning mobile apps, cloud services, APIs, and data platforms. You will act as the technical anchor across product, software, regulatory, and quality teams.

You will mentor engineers, drive requirements, risk analysis, and trade studies, ensuring regulatory compliance and robust risk management per ISO 14971.

Qualifications

• Bachelor's degree in a technical discipline.
• Minimum 13+ years of related experience (or 8+ with a Master).
• Experience leading systems engineering across mobile apps, cloud, APIs, and medical devices.

Responsibilities

• Define and govern system architectures, interfaces, and workflows.
• Lead cross-functional programs and product launches.
• Mentor systems engineers and elevate architectural thinking.
• Drive risk management and regulatory alignment (ISO 14971).

Skills

Systems engineering

Architecture leadership

Requirements engineering

Risk management

Cross-functional collaboration

Mentoring

Education

Bachelor’s degree in a technical discipline

Master’s degree in a technical field

PhD in a technical field

Tools

Jama Connect

Jira

TestRail

GitHub

Cameo

Sparx EA

SysML

Ketryx

Job description

The Company Dexcom Corporation (NASDAQ DXCM) is a pioneer and global leader in continuous glucose monitoring (CGM). Dexcom began as a small company with a big dream: To forever change how diabetes is managed. To unlock information and insights that drive better health outcomes. Here we are 25 years later, having pioneered an industry. And we're just getting started. We are broadening our vision beyond diabetes to empower people to take control of health. That means personalized, actionable insights aimed at solving important health challenges. To continue what we've started: Improving human health. We are driven by thousands of ambitious, passionate people worldwide who are willing to fight like warriors to earn the trust of our customers by listening, serving with integrity, thinking big, and being dependable. We've already changed millions of lives and we're ready to change millions more. Our future ambition is to become a leading consumer health technology company while continuing to develop solutions for serious health conditions. We'll get there by constantly reinventing unique biosensing-technology experiences. Though we've come a long way from our small company days, our dreams are bigger than ever. The opportunity to improve health on a global scale stands before us.

Meet the team

Join our world-class Systems Engineering team as we shape the future of connected diabetes management. As a Senior Staff Systems Engineer, you will serve as a technical leader and systems architect for Dexcom's next-generation digital ecosystem, spanning Mobile Applications, SDKs, Cloud Services, Data Platforms, Partner Integrations, and connected CGM products. This role is ideal for a seasoned Systems Engineering technical leader who thrives in ambiguity, can navigate highly complex cross-functional programs, and is passionate about driving architecture, requirements, risk management, and technical strategy across multiple concurrent initiatives. You will act as the technical anchor for software-centric systems, partnering closely with Product Management, Software Engineering, Clinical, Regulatory, Quality, Cybersecurity, Data Platform, and Commercial teams to deliver innovative solutions that improve the lives of people living with diabetes. Beyond project execution, you will serve as a mentor, coach, and advocate for Systems Engineering excellence across the organization. If you are equally comfortable discussing cloud architecture, mobile application design, system requirements, risk analysis, and executive-level strategy, this is your opportunity to make a lasting impact.

Where you come in

You will serve as the Systems Engineering architect and technical lead for Dexcom's connected ecosystem, driving architecture and design decisions across Mobile Applications (iOS/Android), SDKs, Backend Services, Cloud Infrastructure, APIs, and partner integrations. You will lead the definition, decomposition, and governance of system architectures, requirements, interfaces, and workflows for complex, software-intensive medical device systems. You will own and drive resolution of highly complex cross-functional initiatives, including user-facing experiences such as alerts, notifications, data sharing, interoperability, and connected product functionality. You will serve as the primary Systems Engineering leader across multiple concurrent programs and commercial product launches, balancing technical priorities, architectural tradeoffs, schedule constraints, and regulatory requirements. You will develop and maintain system-level requirements, interface specifications, operational concepts, architecture views, and traceability strategies while ensuring alignment with product needs, user workflows, and risk controls. You will lead system-level risk identification and mitigation activities, working closely with Quality, Regulatory Affairs, Human Factors, Cybersecurity, and Software Engineering teams to proactively address product risks. You will champion robust requirements engineering practices using Jama Connect and establish scalable approaches for requirement quality, traceability, impact assessment, and change management across product portfolios. You will mentor Systems Engineers across all experience levels, helping elevate architectural thinking, systems modeling, requirements development, technical problem solving, and risk management capabilities throughout the organization. You will advocate for Systems Engineering as a strategic technical discipline by driving technical leadership, facilitating architecture reviews, enabling informed decision-making, and influencing organizational direction beyond traditional documentation activities.

What makes you successful

You possess expert-level Systems Engineering knowledge and have successfully architected and delivered large-scale, connected software-enabled products comprising Mobile Apps, Cloud Services, APIs, Backend Platforms, and embedded devices. You demonstrate exceptional systems thinking and can rapidly connect business objectives, user needs, technical constraints, regulatory requirements, and operational considerations into a cohesive system architecture. You have deep experience defining and managing requirements for software-intensive systems, including complex user workflows, data flows, alerts and notifications, connectivity, interoperability, and cloud-based services. You possess strong architectural expertise across modern software ecosystems including mobile applications, SDKs, cloud platforms, web services, data platforms, microservices, security frameworks, and system integrations. You are highly effective at driving technical alignment across diverse stakeholders and can navigate ambiguity, conflicting priorities, and organizational complexity while maintaining forward momentum. You have demonstrated success leading multiple high-visibility projects simultaneously while providing technical leadership, work direction, and coaching to engineers across disciplines. You have extensive experience applying risk management principles in accordance with ISO 14971 and can effectively lead hazard analysis, software risk assessments, interface risk evaluations, and system-level trade studies. You are an outstanding communicator capable of influencing engineers, architects, functional managers, program leaders, and executive stakeholders through data-driven recommendations and well-structured technical arguments. You have a proven ability to transform struggling or ambiguous programs into structured, executable plans by driving architectural clarity, requirements maturity, ownership alignment, and technical accountability. You are recognized as a mentor and force multiplier who develops technical talent, strengthens Systems Engineering culture, and helps establish best practices across the organization.

Nice to haves

• INCOSE CSEP/ESEP certification, MBSE experience (Cameo, Sparx EA, SysML), or equivalent systems architecture expertise.
• Hands-on experience with Jama Connect, Jira, TestRail, GitHub, Ketryx, and modern product lifecycle management tools.
• Experience architecting regulated mobile health, digital health, Software as a Medical Device (SaMD), or connected medical device ecosystems.
• Experience with mobile application architecture (Android/iOS), SDK development, cloud platforms (AWS/Azure/GCP), backend services, APIs, and distributed systems.
• Strong understanding of interoperability technologies including Bluetooth Low Energy (BLE), partner integrations, third-party APIs, and connected device ecosystems.
• Experience supporting commercial product launches, sustaining engineering activities, field issue investigations, and post-market design changes.
• Experience with cybersecurity considerations for connected medical devices, cloud-hosted systems, and consumer mobile applications.
• Experience implementing AI-assisted Systems Engineering, requirements generation, traceability automation, or architecture analysis workflows.
• Experience supporting global product portfolios and leading geographically distributed engineering teams.

What you’ll get

• A front row seat to life changing CGM technology.
• Learn about our brave #dexcomwarriors community.
• A full and comprehensive benefits program.
• Growth opportunities on a global scale.
• Access to career development through in-house learning programs and/or qualified tuition reimbursement.
• An exciting and innovative, industry-leading organization committed to our employees, customers, and the communities we serve.

Travel Required

0-5%

Education and Experience

Typically requires a Bachelor’s degree in a technical discipline, and a minimum of 13+ years related experience or a Master’s degree and 8+ years equivalent industry experience or a PhD and 5+ years of experience.

Remote Workplace

Your location will be a home office; you are not required to live within commuting distance of your assigned Dexcom site (typically 75 miles/120km). If you reside within commuting distance of a Dexcom site (typically 75 miles/120km) a hybrid working environment may be available. Ask about our Flex workplace option.

Please note: The information contained herein is not intended to be an all-inclusive list of the duties and responsibilities of the job, nor are they intended to be an all-inclusive list of the skills and abilities required to do the job. Management may, at its discretion, assign or reassign duties and responsibilities to this job at any time. The duties and responsibilities in this job description may be subject to change at any time due to reasonable accommodation or other reasons. Reasonable accommodations may be made to enable individuals with disabilities to perform essential functions.

An Equal Opportunity Employer.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Dexcom’s AAP may be viewed upon request by contacting Talent Acquisition at [e-mail].

If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact Dexcom Talent Acquisition at [e-mail].

Meritain, an Aetna Company, creates and publishes the Machine-Readable Files on behalf of Dexcom. To link to the Machine-Readable Files, please click on the URL provided: https://health1.meritain.com/app/public/#/one/insurerCode=MERITAIN_I&brandCode=MERITAINOVER/machine-readable-transparency-in-coverage?reportingEntityType=TPA_19874&lock=true

AI in Hiring Notice: We may use AI supported tools to help make our hiring process more efficient, consistent, and accessible for candidates around the world. All hiring decisions are made by people.

Salary: $149,000.00 - $248,300.00 #DexcomUS Since 1999, Dexcom has simplified and revolutionized diabetes management, positively impacting millions worldwide. At Dexcom, we're more than just a medical device company; we're a collective of visionary thinkers, trailblazers, and problem solvers. Our mission transcends the ordinary. We aim to revolutionize healthcare, one groundbreaking technology at a time.