Senior Solid-State Materials Lead – Drug Substances

Initial Therapeutics, Inc.; Indianapolis (IN); On-site; USD 126,000 - 205,000; Full time

Job summary

Lilly is seeking a materials scientist to join the SMDD team in Indianapolis. The role focuses on solid-state science, including solid-form screening and crystallization of small molecules and peptides, with emphasis on process understanding for drug substances.

Ideal candidates hold a PhD in a physical science or a Master’s with 5+ years’ experience and are familiar with XRPD, DSC, TGA, DVS, and HPLC. The position includes strong collaboration, problem-solving, and contributions to development

Qualifications

• PhD in physical science (chemistry/pharmaceutics) or MS with 5+ years experience required.
• Solid-state analytical tools like XRPD, DSC, TGA, DVS, HPLC preferred.
• Experience with solid form screening including crystallization, salts, and/or cocrystals.

Responsibilities

• Solid-form screening and characterization of novel small molecules, peptides, oligonucleotides, and intermediates.
• Scale up crystallization of small molecules and peptide fragments.
• Consultant for project teams solving complex technical problems related to solid form assessment and particle properties.
• Develop workflows for solid-state integration with automated data analysis.
• Document scientific results and maintain lab areas/instrumentation.

Skills

Solid-state science

Crystallization

Data analysis

Communication

Education

PhD in physical science

Masters with 5+ years experience

Tools

XRPD

DSC

TGA

DVS

HPLC

EasyMax

Crystal 16

Job description

Lilly is seeking a materials scientist to join the SMDD team in Indianapolis. The role focuses on solid-state science, including solid-form screening and crystallization of small molecules and peptides, with emphasis on process understanding for drug substances.

Ideal candidates hold a PhD in a physical science or a Master’s with 5+ years’ experience and are familiar with XRPD, DSC, TGA, DVS, and HPLC. The position includes strong collaboration, problem-solving, and contributions to development