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Caris Life Sciences in Irving, TX is seeking a Senior Software Engineer for Clinical Software Products. You will deliver senior‑level engineering across the clinical application portfolio, focusing on data integrity, regulated workflows, and rapid modernization of production systems.
Onboarding emphasizes safety, and the role reports to a Senior Engineering Manager within Clinical Software Engineering. This on‑site/hybrid position requires three days on campus, co‑located with laboratory and
At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting‑edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.
Caris Life Sciences serves hundreds of thousands of molecular cases a year and continues to grow at double-digit rates. Its molecular, imaging, and clinical‑outcomes data support software that helps ensure a cancer patient’s report is right, complete, and on time. The Senior Software Engineer - Clinical Software Products delivers senior‑level engineering across Caris’s clinical application portfolio: product delivery, reliability, and incremental modernization of the production systems that support regulated clinical workflows. This assignment supports the case‑management and order‑intake platform: the order front door and case‑lifecycle services every case runs through on its way to a report. Engineers deliver features and integrations across an actively modernizing platform, with emphasis on data integrity, controlled change, and order‑to‑report throughput. The engineering environment supports advanced AI coding assistants and agentic workflows across design, implementation, and test generation. Characterization tests and golden‑master replay validation provide executable evidence. Onboarding is harness‑first: the engineer builds or extends characterization tests to capture current behavior as repeatable validation evidence. Delivery runs on CI/CD, automated testing, application‑level observability, and risk‑based release governance aligned with current FDA Computer Software Assurance guidance. Representative technologies across the portfolio include Java, TypeScript, browser‑based application frameworks, server‑side JavaScript, and selected enterprise Java components. The interview process covers the specific assignment and technology stack. Reporting to an Engineering Manager or Senior Engineering Manager within Clinical Software Engineering, this senior individual contributor designs, builds, and maintains clinical software applications governed by SOX financial controls and FDA regulatory requirements. The role leads technical delivery on an assigned product team, participates in architecture and design decisions, and upholds the engineering and compliance standards those systems require. Location: Irving, Texas (Dallas-Fort Worth), on‑site/hybrid, minimum three days per week on campus; co‑located with Caris’s laboratory and clinical operations.
Ability to sit, stand, and work at a computer for extended periods.
All job‑specific, safety, and compliance training is assigned based on the job functions associated with this employee.
This role may require periodic travel to other Caris sites or partner locations. After‑hours response to emergency production issues and participation in periodic scheduled on‑call rotations may be required.
Individual must successfully complete pre‑employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.
Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
Caris Life Sciences is a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine through quality and innovation. Caris is committed to quality and excellence at our state‑of-the‑art laboratories. Learn more about our tissue lab and the advanced technologies that are helping improve the lives of cancer patients.