Senior Software Engineer, Agentic Systems

Asepha; New York (NY); Hybrid; USD 150,000 - 300,000; Full time

Benefits offered by this job

Salary + stocks

Health benefits

Unlimited PTO

Off-site trips

Office meals

Dev stipend

Job summary

Asepha, based in New York, seeks a Senior Software Engineer to join its Agentic Systems team in Manhattan. Hybrid, full-time, backend-heavy role shaping AI-powered pharmacy workflows with real-time processing and cross-system orchestration.

You will own end-to-end engineering, design autonomous agents, and build scalable infrastructure across Azure/AWS/GCP while collaborating with frontend, devops, and product teams. Must be located in New York and commute to the office 3 days weekly.

Qualifications

• Minimum 5+ years of software engineering experience with backend focus.
• Proficiency in Python or TypeScript and backend fundamentals.
• Experience with web frameworks and API design (FastAPI, Flask, etc.).
• Familiarity with caching, messaging, and database technologies (Redis, Kafka, SQL/NoSQL, vector databases).
• Experience building for cloud infrastructure (Azure, AWS, or GCP).
• Experience building and deploying agentic AI systems with planning and orchestration.

Responsibilities

• Design and build autonomous agents that handle complex, multi-step pharmaceutical workflows end-to-end
• Architect communication systems that coordinate across organizational boundaries
• Build robust orchestration layers for long-running tasks with graceful failure handling and human-in-the-loop escalation
• Develop frameworks that let agents interact with external pharmacy systems, databases, and APIs
• Implement evaluation and observability infrastructure to monitor agent behavior in production
• Integrate with healthcare data standards and legacy pharmacy systems
• Scale systems to handle real-time processing across multiple pharmacy networks

Skills

5+ years backend experience

Python or TypeScript

Backend fundamentals & distributed

Agentic AI systems knowledge

End-to-end ownership

Cloud infra experience

Tools

Redis

Kafka

SQL/NoSQL

Vector databases

FastAPI/Flask

Job description

Senior Software Engineer, Agentic Systems

Manhattan, NY

Engineering

Hybrid

Full-time

Asepha is based in New York and Toronto, building agentic solutions that re-imagine how medications are prescribed, verified, and supported across the pharmacy ecosystem. Backed by $4M in funding and trusted by multiple Fortune 50 healthcare organizations, we’re scaling rapidly and seeking a talented, innovative Senior Software Engineer to join our growing team. As one of our early hires, you’ll play a critical role in shaping our engineering efforts, making key architectural decisions and writing code to expand our AI product line. You will play a pivotal role in balancing speed of execution with product quality, and have the opportunity to wear multiple hats, from frontend and backend development to devops and customer interactions. Your work will have a direct impact on improving pharmacy workflows and health outcomes.

Join our mission:

We’re building a world where medication delays are impossible. From the moment a prescription is written, the path to therapy start is clear, fast, and predictable. Asepha is the context graph for the therapy-start journey, connecting the fragmented steps that slow down medication access: intake, coordination, utilization management, and clinical services.

Role and Responsibilities:

• Design and build autonomous agents that handle complex, multi-step pharmaceutical workflows end-to-end


• Architect communication systems that coordinate across organizational boundaries


• Build robust orchestration layers for long-running tasks with graceful failure handling and human-in-the-loop escalation


• Develop frameworks that let agents interact with external pharmacy systems, databases, and APIs


• Implement evaluation and observability infrastructure to monitor agent behavior in production


• Integrate with healthcare data standards and legacy pharmacy systems


• Scale systems to handle real-time processing across multiple pharmacy networks

Qualifications:

• 5+ years of experience in software engineering with strong backend focus


• Proficiency in Python or TypeScript and deep knowledge of backend fundamentals: APIs, data stores, concurrency, distributed systems


• Experience with web frameworks and service-oriented architectures (FastAPI, Flask, or equivalent) and designing clean, versioned APIs


• Familiarity with caching, messaging, and database technologies (Redis, Kafka, SQL/NoSQL, vector databases) and how to use them for performance and reliability


• Experience building for cloud infrastructure (Azure, AWS, or GCP)


• Experience building and deploying agentic AI systems. You understand tool use, planning, memory, and orchestration patterns


• You’ve built systems where the hardest part wasn’t the code, it was figuring out what to build


• You’ve shipped something end-to-end with minimal guidance and owned the outcome


• Located in New York and can commute to our Manhattan office 3 days per week

Perks:

• Competitive compensation package, including $150-300k USD annual salary + stock options


• Full medical, dental, vision, and extended health benefits


• Unlimited days off to maintain a healthy work-life balance + 2 weeks of company-wide office closure during the holidays


• 2 annual off-site trips with the team


• Complimentary breakfast and lunch provided daily in the office. Dinner also provided if staying past 7pm.


• Professional development stipend

Compensation

The base pay range for this role is $150,000 – $300,000 per year.

Note: Only candidates selected for an interview will be contacted.

Asepha is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity or expression, religion, national origin or ancestry, age, disability, marital status, pregnancy, protected veteran status, protected genetic information, political affiliation, or any other characteristics protected by local laws, regulations, or ordinances.