Senior Scientist - Virology (Contractor)

Transfyr Bio; Cambridge (MA); On-site; USD 61,992 - 103,320; Full time

Job summary

Transfyr Bio is seeking a Senior Scientist specializing in Virology to conduct in-depth lab experiments and provide expertise in molecular biology. This role involves designing reverse genetics systems and optimizing assays while ensuring compliance with safety standards. The ideal candidate will hold a PhD or equivalent experience, with proven expertise in wet lab techniques. The position is located in Cambridge, MA, with part-time and full-time options available, offering a competitive hourly wage of $45-75 depending on experience.

Qualifications

• PhD in Virology, Molecular Biology, Computational Biology, or related field.
• Demonstrated lab experience designing viral reverse genetics systems.
• Ability to troubleshoot lab protocols systematically.

Responsibilities

• Conduct wet-lab experiments to support virology workflows.
• Design and implement reverse genetics systems for viruses.
• Uphold BSL-2 safety standards in the lab.

Skills

Virology expertise

Molecular biology workflows

Experimental design

Documentation and reproducibility

Education

PhD or equivalent experience

MS with 3+ years experience

BS with 5+ years experience

Tools

PCR

RT-qPCR

Gene manipulation

Job description

Senior Scientist – Virology (Contractor)

Location: On-site, Cambridge MA (Kendall Square); no flexibility for remote or hybrid work
Hours: Part-time (20h/week) or full-time (40h/week) contracts under consideration
Temporary: Fixed 8-12 week term, starting as early as May 15, 2026
Salary: $45-75/h (pay is based on a 40 hour per week schedule and depends on experience/expertise)
Level: Subject Matter Expert (PhD or 5+ years of relevant industry experience)

About the Role

• We’re looking for a hands‑on Senior Scientist with expertise in virology and molecular biology workflows to conduct wet‑lab experiments in our facility.
• You’ll be embedded in day‑to‑day lab operations to support the design and execution of experiments, uncover edge cases in protocols, and collaborate with AI, biology, and data engineers to help build the infrastructure behind fast, reproducible science.
• This is a true doer role in an early‑stage startup. You will assist in the design and execution of reverse genetics‑based plasmid virus production systems, assay development, troubleshooting and process optimization, and quality control.

What you’ll accomplish with us:

• Reverse Genetics: Design and implement reverse genetics systems for multiple virus families.
• Assay Design & Execution: Design, perform, and optimize molecular and virology assays including plaque assays, reporter assays, nucleic acid extraction, PCR, RT‑qPCR, cloning, gene manipulation, and sequencing to evaluate viral genomes.
• Troubleshoot laboratory protocols: support documentation, troubleshooting, and process improvements to enhance workflow reproducibility.
• Safety and Compliance: Uphold rigorous BSL‑2 safety standards.

Requirements:

• PhD, or MS with 3+ years of relevant experience, or BS with 5+ years of relevant experience in Virology, Molecular Biology, Computational Biology, Bioengineering Biology, or related field.
• Demonstrated hands‑on lab experience (industry or academic) with the required wet lab techniques, including a track record of designing and using viral reverse genetics systems and plasmids.
• Exceptional experimental design with a strong bias toward documentation, reproducibility, and iteration.
• Ability to troubleshoot protocols systematically, with attention to both technical detail and human variability.
• Ability to clearly communicate technical concepts to cross‑functional teams and collaborate on projects spanning AI, biology, and product.
• Located within commuting distance from Cambridge, MA.

Nice to Have

• Startup or early‑stage experience preferred; comfort with ambiguity and rapid iteration is a must.
• Coding experience for complex data analysis and statistics (python, R, ).
• Demonstrated experience using AI/ML tools for experimental design, data analysis, or predictive modeling.
• Direct customer‑facing work in partner or external lab environments.