Senior Scientist, Viral Vector Purification & Downstream

Sanofi; Waltham, Northern (MA, KY); Hybrid; USD 75,000 - 108,000; Full time

Job summary

Sanofi in Waltham, MA seeks a Senior Research Associate for Downstream Process Development to advance viral vector purification processes and assist technology transfer to manufacturing. The role emphasizes leading studies, optimizing purification steps, and collaborating with CS/QA and external partners.

The candidate will design experiments, analyze data, and contribute to manuscripts and regulatory-ready documentation in a fast-paced, GMP-regulated environment.

Qualifications

• Experience in viral vector purification including AAV is preferred.
• Strong knowledge of downstream purification techniques and unit operations.
• Excellent documentation and technical reporting skills.
• GLP familiarity and ability to work in a regulated environment.

Responsibilities

• Develop and optimize viral vector purification processes and scale-up strategies.
• Lead studies and assist tech transfer to manufacturing teams.
• Design experiments and analyze data to improve product yield.
• Collaborate cross-functionally with RD, QA, and CDMOs.

Skills

AAV purification

Downstream purification

Scale-up experience

Tech transfer

DOE design of experiments

Problem solving

Education

Bachelor's or Master's degree in Chemical Engineering, Biological Sciences, or related field

Tools

AKTA

TFF/UF-DF

HPLC

SDS-PAGE

ELISA

Virus purification

Job description

Sanofi in Waltham, MA seeks a Senior Research Associate for Downstream Process Development to advance viral vector purification processes and assist technology transfer to manufacturing. The role emphasizes leading studies, optimizing purification steps, and collaborating with CS/QA and external partners.

The candidate will design experiments, analyze data, and contribute to manuscripts and regulatory-ready documentation in a fast-paced, GMP-regulated environment.