Senior Scientist: Stem Cell Process Development

HexemBio; Berkeley (CA); On-site; USD 120,000 - 190,000; Full time

Benefits offered by this job

Competitive salary

Meaningful equity

Benefits package

Job summary

HexemBio is seeking a Senior Scientist to lead process development for stem cell programs. This hands-on role offers ownership to design and execute bench work, define scalable culture processes, and work directly with the founders to advance regenerative medicine platforms.

The candidate will drive in-process controls, develop assays, and mentor junior staff while aligning with regulatory considerations and CDMO collaborations. Strong biology background and leadership are essential.

Qualifications

• PhD or MD/PhD in stem cell biology or related field.
• At least 3 years of industry experience in cell therapy or regenerative medicine process development.
• Proven track record in pluripotent stem cell work (publications, patents, or comparable accomplishments).
• Hands-on bench expertise in large-scale cell culture, flow cytometry, CFU assays, qPCR, and molecular biology.
• Familiarity with cGMP concepts, in-process controls, assay qualification, and documentation practices.
• Genuine bench expertise and intent to keep doing it.
• Willingness to work around timepoint demands of primary/pluripotent cell culture, including occasional weekends.
• Track record of moving fast without losing rigor in an early-stage environment.
• Foundational role contributing to platform/process definitions.
• Direct collaboration with founders and an advisory network.

Responsibilities

• Develop, optimize, and document scalable culture processes for pluripotent stem cell derived material and primary hematopoietic cells.
• Drive in-process controls, critical process parameters, and release assays from bench scale toward clinical scale.
• Execute and troubleshoot at the bench across differentiation, expansion, harvest, and formulation steps.
• Design characterization and potency assays and interpret data for program/regulatory decisions.
• Support tech transfer to CDMO partners and contribute to CMC sections of regulatory filings.
• Train and mentor junior scientists at the bench.
• Collaborate with leadership to set research priorities and scientific direction.

Skills

Cell culture at scale

Flow cytometry

Colony Forming Unit assays

qPCR

Molecular biology

cGMP concepts

Education

PhD or MD/PhD in stem cell biology, cell biology, bioengineering, or related field

Job description

HexemBio is seeking a Senior Scientist to lead process development for stem cell programs. This hands-on role offers ownership to design and execute bench work, define scalable culture processes, and work directly with the founders to advance regenerative medicine platforms.

The candidate will drive in-process controls, develop assays, and mentor junior staff while aligning with regulatory considerations and CDMO collaborations. Strong biology background and leadership are essential.