Senior Scientist, Precision Oncology & Target Discovery
Amgen Inc.
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Benefits offered by this job
Job summary
Amgen seeks a Senior Scientist in Precision Oncology to lead experimental strategy for oncology programs, shaping evidence for new therapeutic hypotheses. You will collaborate with biology, chemistry, computational sciences, pharmacology, and translational sciences to translate biological insights into impactful discoveries.
The role emphasizes creativity, rigorous experimental design, and cross-functional teamwork within a collaborative, science-driven culture.
Qualifications
- PhD in Cancer Biology, Cell Biology, Molecular Biology, Genetics, Chemical Biology, or related discipline, with 1–3 years postdoc/industry experience.
- Strong background in cancer cell biology, cell signaling, mechanistic pharmacology, and small-molecule oncology drug discovery, with publications or patents.
- Subject matter expertise in advanced CRISPR technologies and genome engineering.
- Expertise in advanced imaging technologies including high-content imaging, quantitative microscopy, live-cell imaging, and image-analysis workflows.
- Experience developing and applying high-throughput cellular and biochemical assays, including assay optimization and QC.
- Excellent experimental design, data analysis, troubleshooting, communication, and collaboration skills.
- Demonstrated scientific creativity and success in multidisciplinary research environments.
Responsibilities
- Design and execute studies to validate oncology targets and define mechanisms of action.
- Apply CRISPR genome-editing to establish target function and dependencies.
- Evaluate emerging technologies and AI tools to accelerate discovery.
- Develop quantitative assays to investigate target engagement and pathway modulation.
- Analyze complex data and communicate insights to multidisciplinary teams.
- Collaborate across research groups to advance oncology drug discovery.
Skills
Education
Tools
Job description
Amgen seeks a Senior Scientist in Precision Oncology to lead experimental strategy for oncology programs, shaping evidence for new therapeutic hypotheses. You will collaborate with biology, chemistry, computational sciences, pharmacology, and translational sciences to translate biological insights into impactful discoveries.
The role emphasizes creativity, rigorous experimental design, and cross-functional teamwork within a collaborative, science-driven culture.
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