Senior Oncology Research Leader - TCE/ADC Innovator

Amgen Inc.; South San Francisco (CA); On-site; USD 191,000 - 258,000; Full time

Benefits offered by this job

Retirement plan

Bonus program

Stock-based incentives

Flexible work models

Job summary

Amgen Inc. is seeking a Scientific Associate Director, Oncology Research to lead a portfolio of antibody-based oncology programs.

You will guide cross-functional discovery, integrate translational biology, and shape development strategies for TCE/ADC therapies in solid tumors, including pancreatic cancer. You will mentor scientists, deliver rigorous science, and communicate strategy to senior stakeholders in a fast-paced matrix environment.

Qualifications

• Basic Qualifications: Doctorate degree PhD OR PharmD OR MD with 4 years of relevant experience OR Master’s with 7 years OR Bachelor’s with 9 years.
• Preferred Qualifications: PhD or equivalent in cancer biology, immunology, molecular biology, pharmacology, genetics, translational medicine or related discipline.
• Experience leading oncology TCE and/or ADC programs from discovery to nomination or major milestone.
• Deep knowledge of solid-tumor biology, pancreatic cancer or other treatment-resistant tumors.
• Strong understanding of antibody-based discovery, including TCEs/ADCs, protein engineering, pharmacology, safety, biomarkers, and clinical-development considerations.

Responsibilities

• Define and lead preclinical research strategies for TCE and ADC therapies and prioritize discovery investments.
• Lead cell-surface target discovery and validation strategy for pancreatic cancer for first-in-class TCE/ADC therapies.
• Serve as Project Team Lead for Oncology portfolio programs, set objectives, monitor milestones, and adapt strategy with new data.
• Lead and develop a lab-based team, promoting rigorous science, execution, risk-taking, and professional growth.

Education

PhD/MD/PharmD

Master's degree + 7 yrs

Bachelor's + 9 yrs

Job description

Amgen Inc. is seeking a Scientific Associate Director, Oncology Research to lead a portfolio of antibody-based oncology programs.

You will guide cross-functional discovery, integrate translational biology, and shape development strategies for TCE/ADC therapies in solid tumors, including pancreatic cancer. You will mentor scientists, deliver rigorous science, and communicate strategy to senior stakeholders in a fast-paced matrix environment.