Senior Scientist: Oncology Targeted Discovery Lead

AstraZeneca plc; Gaithersburg (MD); On-site; USD 112,000 - 169,000; Full time

Job summary

AstraZeneca plc in Gaithersburg, MD seeks a Senior Scientist in Oncology Targeted Discovery to lead target validation for tumor-targeted therapies. You will work with cross-functional teams to generate data critical for milestone decisions, and perform in vitro studies using diverse biochemical and cellular techniques to understand mechanisms in cancer biology.

Ideal candidates have a Ph.D. with relevant experience or a Master’s with extensive lab work, strong communication, and a drive to

Qualifications

• Ph.D. or Master’s with required experience in cancer biology or related field.
• Strong background in cell biology, biochemistry, and molecular biology.
• Proven bench skills in mammalian cell culture and molecular assays.
• Excellent communication and teamwork in a fast-paced matrix environment.
• Commitment to GLP, safety, and regulatory standards.

Responsibilities

• Lead target validation for one or more pipeline programs.
• Collaborate with cross-functional teams to ensure timely data delivery for milestones.
• Design, perform, and analyze in vitro experiments to validate targets.
• Stay current with cancer biology, disease models, and therapeutics.
• Operate as a collaborative, data-driven team member.

Skills

Cell biology

Molecular biology

Biochemistry

Mammalian cell culture

Flow cytometry

Western blot

qPCR

ELISA

Fluorescence microscopy

CRISPR/Cas9

Communication

Education

Ph.D. in relevant field

Masters in relevant field

Tools

Laboratory automation

CRISPR/Cas9 techniques

Job description

AstraZeneca plc in Gaithersburg, MD seeks a Senior Scientist in Oncology Targeted Discovery to lead target validation for tumor-targeted therapies. You will work with cross-functional teams to generate data critical for milestone decisions, and perform in vitro studies using diverse biochemical and cellular techniques to understand mechanisms in cancer biology.

Ideal candidates have a Ph.D. with relevant experience or a Master’s with extensive lab work, strong communication, and a drive to